Nanoparticle synthesis and their integration into polymer-based fibers for biomedical applications

Detalhes bibliográficos
Autor(a) principal: Domingues, Joana Margarida Dias
Data de Publicação: 2023
Outros Autores: Miranda, Catarina S., Homem, Natália Cândido, Felgueiras, Helena Prado, Antunes, Joana Isabel Costa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/1822/85471
Resumo: The potential of nanoparticles as effective drug delivery systems combined with the versatility of fibers has led to the development of new and improved strategies to help in the diagnosis and treatment of diseases. Nanoparticles have extraordinary characteristics that are helpful in several applications, including wound dressings, microbial balance approaches, tissue regeneration, and cancer treatment. Owing to their large surface area, tailor-ability, and persistent diameter, fibers are also used for wound dressings, tissue engineering, controlled drug delivery, and protective clothing. The combination of nanoparticles with fibers has the power to generate delivery systems that have enhanced performance over the individual architectures. This review aims at illustrating the main possibilities and trends of fibers functionalized with nanoparticles, focusing on inorganic and organic nanoparticles and polymer-based fibers. Emphasis on the recent progress in the fabrication procedures of several types of nanoparticles and in the description of the most used polymers to produce fibers has been undertaken, along with the bioactivity of such alliances in several biomedical applications. To finish, future perspectives of nanoparticles incorporated within polymer-based fibers for clinical use are presented and discussed, thus showcasing relevant paths to follow for enhanced success in the field.
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spelling Nanoparticle synthesis and their integration into polymer-based fibers for biomedical applicationsNanoparticlesPolymer-based fibersFunctionalizationBioactivityBiomedical applicationsEngenharia e Tecnologia::Engenharia dos MateriaisSaúde de qualidadeThe potential of nanoparticles as effective drug delivery systems combined with the versatility of fibers has led to the development of new and improved strategies to help in the diagnosis and treatment of diseases. Nanoparticles have extraordinary characteristics that are helpful in several applications, including wound dressings, microbial balance approaches, tissue regeneration, and cancer treatment. Owing to their large surface area, tailor-ability, and persistent diameter, fibers are also used for wound dressings, tissue engineering, controlled drug delivery, and protective clothing. The combination of nanoparticles with fibers has the power to generate delivery systems that have enhanced performance over the individual architectures. This review aims at illustrating the main possibilities and trends of fibers functionalized with nanoparticles, focusing on inorganic and organic nanoparticles and polymer-based fibers. Emphasis on the recent progress in the fabrication procedures of several types of nanoparticles and in the description of the most used polymers to produce fibers has been undertaken, along with the bioactivity of such alliances in several biomedical applications. To finish, future perspectives of nanoparticles incorporated within polymer-based fibers for clinical use are presented and discussed, thus showcasing relevant paths to follow for enhanced success in the field.This research was funded by the Portuguese Foundation for Science and Technology (FCT) via grants UIDP/00264/2020 of 2C2T Strategic Project 2020–2023 and project PTDC/CTMTEX/28074/2017. This project has been funded by a Research Grant (2022) from the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) to J.C.A., J.M.D. and C.S.M. also acknowledge FCT for PhD grants 2020.07387.BD and 2020.08547.BD, respectively, and H.P.F. for auxiliary researcher contract 2021.02720.CEECIND.Multidisciplinary Digital Publishing Institute (MDPI)Universidade do MinhoDomingues, Joana Margarida DiasMiranda, Catarina S.Homem, Natália CândidoFelgueiras, Helena PradoAntunes, Joana Isabel Costa2023-06-232023-06-23T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/85471engDomingues, J.M.; Miranda, C.S.; Homem, N.C.; Felgueiras, H.P.; Antunes, J.C. Nanoparticle Synthesis and Their Integration into Polymer-Based Fibers for Biomedical Applications. Biomedicines 2023, 11, 1862. https://doi.org/10.3390/biomedicines110718622227-905910.3390/biomedicines110718621862https://www.mdpi.com/2227-9059/11/7/1862info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T11:55:27Zoai:repositorium.sdum.uminho.pt:1822/85471Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:45:00.175834Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Nanoparticle synthesis and their integration into polymer-based fibers for biomedical applications
title Nanoparticle synthesis and their integration into polymer-based fibers for biomedical applications
spellingShingle Nanoparticle synthesis and their integration into polymer-based fibers for biomedical applications
Domingues, Joana Margarida Dias
Nanoparticles
Polymer-based fibers
Functionalization
Bioactivity
Biomedical applications
Engenharia e Tecnologia::Engenharia dos Materiais
Saúde de qualidade
title_short Nanoparticle synthesis and their integration into polymer-based fibers for biomedical applications
title_full Nanoparticle synthesis and their integration into polymer-based fibers for biomedical applications
title_fullStr Nanoparticle synthesis and their integration into polymer-based fibers for biomedical applications
title_full_unstemmed Nanoparticle synthesis and their integration into polymer-based fibers for biomedical applications
title_sort Nanoparticle synthesis and their integration into polymer-based fibers for biomedical applications
author Domingues, Joana Margarida Dias
author_facet Domingues, Joana Margarida Dias
Miranda, Catarina S.
Homem, Natália Cândido
Felgueiras, Helena Prado
Antunes, Joana Isabel Costa
author_role author
author2 Miranda, Catarina S.
Homem, Natália Cândido
Felgueiras, Helena Prado
Antunes, Joana Isabel Costa
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Domingues, Joana Margarida Dias
Miranda, Catarina S.
Homem, Natália Cândido
Felgueiras, Helena Prado
Antunes, Joana Isabel Costa
dc.subject.por.fl_str_mv Nanoparticles
Polymer-based fibers
Functionalization
Bioactivity
Biomedical applications
Engenharia e Tecnologia::Engenharia dos Materiais
Saúde de qualidade
topic Nanoparticles
Polymer-based fibers
Functionalization
Bioactivity
Biomedical applications
Engenharia e Tecnologia::Engenharia dos Materiais
Saúde de qualidade
description The potential of nanoparticles as effective drug delivery systems combined with the versatility of fibers has led to the development of new and improved strategies to help in the diagnosis and treatment of diseases. Nanoparticles have extraordinary characteristics that are helpful in several applications, including wound dressings, microbial balance approaches, tissue regeneration, and cancer treatment. Owing to their large surface area, tailor-ability, and persistent diameter, fibers are also used for wound dressings, tissue engineering, controlled drug delivery, and protective clothing. The combination of nanoparticles with fibers has the power to generate delivery systems that have enhanced performance over the individual architectures. This review aims at illustrating the main possibilities and trends of fibers functionalized with nanoparticles, focusing on inorganic and organic nanoparticles and polymer-based fibers. Emphasis on the recent progress in the fabrication procedures of several types of nanoparticles and in the description of the most used polymers to produce fibers has been undertaken, along with the bioactivity of such alliances in several biomedical applications. To finish, future perspectives of nanoparticles incorporated within polymer-based fibers for clinical use are presented and discussed, thus showcasing relevant paths to follow for enhanced success in the field.
publishDate 2023
dc.date.none.fl_str_mv 2023-06-23
2023-06-23T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/85471
url https://hdl.handle.net/1822/85471
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Domingues, J.M.; Miranda, C.S.; Homem, N.C.; Felgueiras, H.P.; Antunes, J.C. Nanoparticle Synthesis and Their Integration into Polymer-Based Fibers for Biomedical Applications. Biomedicines 2023, 11, 1862. https://doi.org/10.3390/biomedicines11071862
2227-9059
10.3390/biomedicines11071862
1862
https://www.mdpi.com/2227-9059/11/7/1862
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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