Systematic literature review informing the 2018 update of the EULAR recommendation for the management of large vessel vasculitis : focus on giant cell arteritis

Detalhes bibliográficos
Autor(a) principal: Monti, Sara
Data de Publicação: 2019
Outros Autores: Agueda, Ana, Luqmani, Raashid Ahmed, Buttgereit, Frank, Cid, Maria, Dejaco, Christian, Mahr, Alfred, Ponte, Cristina, Salvarani, Carlo, Schmidt, Wolfgang, Hellmich, Bernhard
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/48406
Resumo: © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
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spelling Systematic literature review informing the 2018 update of the EULAR recommendation for the management of large vessel vasculitis : focus on giant cell arteritisAutoimmune diseasesGiant cell arteritisSystemic vasculitis© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.Objectives: To analyse the current evidence for the management of large vessel vasculitis (LVV) to inform the 2018 update of the EULAR recommendations. Methods: Two systematic literature reviews (SLRs) dealing with diagnosis/monitoring and treatment strategies for LVV, respectively, were performed. Medline, Embase and Cochrane databases were searched from inception to 31 December 2017. Evidence on imaging was excluded as recently published in dedicated EULAR recommendations. This paper focuses on the data relevant to giant cell arteritis (GCA). Results: We identified 287 eligible articles (122 studies focused on diagnosis/monitoring, 165 on treatment). The implementation of a fast-track approach to diagnosis significantly lowers the risk of permanent visual loss compared with historical cohorts (level of evidence, LoE 2b). Reliable diagnostic or prognostic biomarkers for GCA are still not available (LoE 3b).The SLR confirms the efficacy of prompt initiation of glucocorticoids (GC). There is no high-quality evidence on the most appropriate starting dose, route of administration, tapering and duration of GC (LoE 4). Patients with GCA are at increased risk of dose-dependent GC-related adverse events (LoE 3b). The addition of methotrexate or tocilizumab reduces relapse rates and GC requirements (LoE 1b). There is no consistent evidence that initiating antiplatelet agents at diagnosis would prevent future ischaemic events (LoE 2a). There is little evidence to guide monitoring of patients with GCA. Conclusions: Results from two SLRs identified novel evidence on the management of GCA to guide the 2018 update of the EULAR recommendations on the management of LVV.BMJ Publishing Group, Ltd.Repositório da Universidade de LisboaMonti, SaraAgueda, AnaLuqmani, Raashid AhmedButtgereit, FrankCid, MariaDejaco, ChristianMahr, AlfredPonte, CristinaSalvarani, CarloSchmidt, WolfgangHellmich, Bernhard2021-06-08T12:37:05Z20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/48406engRMD Open. 2019 Sep 16;5(2):e00100310.1136/rmdopen-2019-0010032056-5933info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:51:46Zoai:repositorio.ul.pt:10451/48406Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:00:17.975636Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Systematic literature review informing the 2018 update of the EULAR recommendation for the management of large vessel vasculitis : focus on giant cell arteritis
title Systematic literature review informing the 2018 update of the EULAR recommendation for the management of large vessel vasculitis : focus on giant cell arteritis
spellingShingle Systematic literature review informing the 2018 update of the EULAR recommendation for the management of large vessel vasculitis : focus on giant cell arteritis
Monti, Sara
Autoimmune diseases
Giant cell arteritis
Systemic vasculitis
title_short Systematic literature review informing the 2018 update of the EULAR recommendation for the management of large vessel vasculitis : focus on giant cell arteritis
title_full Systematic literature review informing the 2018 update of the EULAR recommendation for the management of large vessel vasculitis : focus on giant cell arteritis
title_fullStr Systematic literature review informing the 2018 update of the EULAR recommendation for the management of large vessel vasculitis : focus on giant cell arteritis
title_full_unstemmed Systematic literature review informing the 2018 update of the EULAR recommendation for the management of large vessel vasculitis : focus on giant cell arteritis
title_sort Systematic literature review informing the 2018 update of the EULAR recommendation for the management of large vessel vasculitis : focus on giant cell arteritis
author Monti, Sara
author_facet Monti, Sara
Agueda, Ana
Luqmani, Raashid Ahmed
Buttgereit, Frank
Cid, Maria
Dejaco, Christian
Mahr, Alfred
Ponte, Cristina
Salvarani, Carlo
Schmidt, Wolfgang
Hellmich, Bernhard
author_role author
author2 Agueda, Ana
Luqmani, Raashid Ahmed
Buttgereit, Frank
Cid, Maria
Dejaco, Christian
Mahr, Alfred
Ponte, Cristina
Salvarani, Carlo
Schmidt, Wolfgang
Hellmich, Bernhard
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Monti, Sara
Agueda, Ana
Luqmani, Raashid Ahmed
Buttgereit, Frank
Cid, Maria
Dejaco, Christian
Mahr, Alfred
Ponte, Cristina
Salvarani, Carlo
Schmidt, Wolfgang
Hellmich, Bernhard
dc.subject.por.fl_str_mv Autoimmune diseases
Giant cell arteritis
Systemic vasculitis
topic Autoimmune diseases
Giant cell arteritis
Systemic vasculitis
description © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-01-01T00:00:00Z
2021-06-08T12:37:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/48406
url http://hdl.handle.net/10451/48406
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv RMD Open. 2019 Sep 16;5(2):e001003
10.1136/rmdopen-2019-001003
2056-5933
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv BMJ Publishing Group, Ltd.
publisher.none.fl_str_mv BMJ Publishing Group, Ltd.
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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