A rare cause of agranulocytosis
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.26/37858 |
Resumo: | Clozapine, an atypical antipsychotic agent, is useful in the treatment of patients with psychotic symptoms. However, severe adverse effects, such as agranulocytosis, can restrict its indications. We present a case of a 42-year-old Caucasian woman with a 4-year history of persistent delusion disorder, who presented with fatigue and fever and was ultimately diagnosed with agranulocytosis due to clozapine. Clozapine-induced granulocytosis is an uncommon condition, but potentially fatal in consequences. Each patient with an episode of agranulocytosis should be assessed individually, with special attention to risk factors. Upon that, the decision about clozapine rechallenge or withdrawal should be made |
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A rare cause of agranulocytosisagranulocytosisClozapineRegião Autónoma da MadeiraClozapine - risk factorsPortugalMadeira IslandClozapine, an atypical antipsychotic agent, is useful in the treatment of patients with psychotic symptoms. However, severe adverse effects, such as agranulocytosis, can restrict its indications. We present a case of a 42-year-old Caucasian woman with a 4-year history of persistent delusion disorder, who presented with fatigue and fever and was ultimately diagnosed with agranulocytosis due to clozapine. Clozapine-induced granulocytosis is an uncommon condition, but potentially fatal in consequences. Each patient with an episode of agranulocytosis should be assessed individually, with special attention to risk factors. Upon that, the decision about clozapine rechallenge or withdrawal should be madeOAT-Open Acess TextRepositório ComumLuís, HelenaBarros, CarolinaFernandes, MauroGranito, Sofia2021-10-29T16:15:45Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/37858engClin Case Rep Rev, 2021 doi: 10.15761/CCRR.10005012059-039310.15761/CCRR.1000501info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-10T02:18:41Zoai:comum.rcaap.pt:10400.26/37858Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:34:35.906812Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
A rare cause of agranulocytosis |
title |
A rare cause of agranulocytosis |
spellingShingle |
A rare cause of agranulocytosis Luís, Helena agranulocytosis Clozapine Região Autónoma da Madeira Clozapine - risk factors Portugal Madeira Island |
title_short |
A rare cause of agranulocytosis |
title_full |
A rare cause of agranulocytosis |
title_fullStr |
A rare cause of agranulocytosis |
title_full_unstemmed |
A rare cause of agranulocytosis |
title_sort |
A rare cause of agranulocytosis |
author |
Luís, Helena |
author_facet |
Luís, Helena Barros, Carolina Fernandes, Mauro Granito, Sofia |
author_role |
author |
author2 |
Barros, Carolina Fernandes, Mauro Granito, Sofia |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Repositório Comum |
dc.contributor.author.fl_str_mv |
Luís, Helena Barros, Carolina Fernandes, Mauro Granito, Sofia |
dc.subject.por.fl_str_mv |
agranulocytosis Clozapine Região Autónoma da Madeira Clozapine - risk factors Portugal Madeira Island |
topic |
agranulocytosis Clozapine Região Autónoma da Madeira Clozapine - risk factors Portugal Madeira Island |
description |
Clozapine, an atypical antipsychotic agent, is useful in the treatment of patients with psychotic symptoms. However, severe adverse effects, such as agranulocytosis, can restrict its indications. We present a case of a 42-year-old Caucasian woman with a 4-year history of persistent delusion disorder, who presented with fatigue and fever and was ultimately diagnosed with agranulocytosis due to clozapine. Clozapine-induced granulocytosis is an uncommon condition, but potentially fatal in consequences. Each patient with an episode of agranulocytosis should be assessed individually, with special attention to risk factors. Upon that, the decision about clozapine rechallenge or withdrawal should be made |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-10-29T16:15:45Z 2021 2021-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.26/37858 |
url |
http://hdl.handle.net/10400.26/37858 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Clin Case Rep Rev, 2021 doi: 10.15761/CCRR.1000501 2059-0393 10.15761/CCRR.1000501 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
OAT-Open Acess Text |
publisher.none.fl_str_mv |
OAT-Open Acess Text |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799134907911372800 |