How chromosomal inversions reorient the evolutionary process
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10451/62608 |
Resumo: | Inversions are structural mutations that reverse the sequence of a chromosome segment and reduce the effective rate of recombination in the heterozygous state. They play a major role in adaptation, as well as in other evolutionary processes such as speciation. Although inversions have been studied since the 1920s, they remain difficult to investigate because the reduced recombination conferred by them strengthens the effects of drift and hitchhiking, which in turn can obscure signatures of selection. Nonetheless, numerous inversions have been found to be under selection. Given recent advances in population genetic theory and empirical study, here we review how different mechanisms of selection affect the evolution of inversions. A key difference between inversions and other mutations, such as single nucleotide variants, is that the fitness of an inversion may be affected by a larger number of frequently interacting processes. This considerably complicates the analysis of the causes underlying the evolution of inversions. We discuss the extent to which these mechanisms can be disentangled, and by which approach |
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How chromosomal inversions reorient the evolutionary processInversions are structural mutations that reverse the sequence of a chromosome segment and reduce the effective rate of recombination in the heterozygous state. They play a major role in adaptation, as well as in other evolutionary processes such as speciation. Although inversions have been studied since the 1920s, they remain difficult to investigate because the reduced recombination conferred by them strengthens the effects of drift and hitchhiking, which in turn can obscure signatures of selection. Nonetheless, numerous inversions have been found to be under selection. Given recent advances in population genetic theory and empirical study, here we review how different mechanisms of selection affect the evolution of inversions. A key difference between inversions and other mutations, such as single nucleotide variants, is that the fitness of an inversion may be affected by a larger number of frequently interacting processes. This considerably complicates the analysis of the causes underlying the evolution of inversions. We discuss the extent to which these mechanisms can be disentangled, and by which approachWileyRepositório da Universidade de LisboaBerdan, Emma L.Barton, Nicholas H.Butlin, RogerCharlesworth, BrianFaria, RuiDe mendonça fragata almeida, InêsGilbert, Kimberly J.Jay, PaulKapun, MartinLotterhos, Katie E.Mérot, ClaireDurmaz Mitchell, EsraPascual, MartaPeichel, Catherine L.Rafajlović, MarinaWestram, Anja M.Schaeffer, Stephen W.Johannesson, KerstinFlatt, Thomas2024-02-14T10:53:45Z2023-122023-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/62608engEmma L. Berdan, Nicholas H. Barton, Roger Butlin, Brian Charlesworth, Rui Faria, Inês Fragata, Kimberly J. Gilbert, Paul Jay, Martin Kapun, Katie E. Lotterhos, Claire Mérot, Esra Durmaz Mitchell, Marta Pascual, Catherine L. Peichel, Marina Rafajlović, Anja M. Westram, Stephen W. Schaeffer, Kerstin Johannesson, Thomas Flatt, How chromosomal inversions reorient the evolutionary process, Journal of Evolutionary Biology, Volume 36, Issue 12, 1 December 2023, Pages 1761–1782, https://doi.org/10.1111/jeb.1424210.1111/jeb.14242info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-19T01:18:59Zoai:repositorio.ul.pt:10451/62608Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:38:57.318261Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
How chromosomal inversions reorient the evolutionary process |
title |
How chromosomal inversions reorient the evolutionary process |
spellingShingle |
How chromosomal inversions reorient the evolutionary process Berdan, Emma L. |
title_short |
How chromosomal inversions reorient the evolutionary process |
title_full |
How chromosomal inversions reorient the evolutionary process |
title_fullStr |
How chromosomal inversions reorient the evolutionary process |
title_full_unstemmed |
How chromosomal inversions reorient the evolutionary process |
title_sort |
How chromosomal inversions reorient the evolutionary process |
author |
Berdan, Emma L. |
author_facet |
Berdan, Emma L. Barton, Nicholas H. Butlin, Roger Charlesworth, Brian Faria, Rui De mendonça fragata almeida, Inês Gilbert, Kimberly J. Jay, Paul Kapun, Martin Lotterhos, Katie E. Mérot, Claire Durmaz Mitchell, Esra Pascual, Marta Peichel, Catherine L. Rafajlović, Marina Westram, Anja M. Schaeffer, Stephen W. Johannesson, Kerstin Flatt, Thomas |
author_role |
author |
author2 |
Barton, Nicholas H. Butlin, Roger Charlesworth, Brian Faria, Rui De mendonça fragata almeida, Inês Gilbert, Kimberly J. Jay, Paul Kapun, Martin Lotterhos, Katie E. Mérot, Claire Durmaz Mitchell, Esra Pascual, Marta Peichel, Catherine L. Rafajlović, Marina Westram, Anja M. Schaeffer, Stephen W. Johannesson, Kerstin Flatt, Thomas |
author2_role |
author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
dc.contributor.author.fl_str_mv |
Berdan, Emma L. Barton, Nicholas H. Butlin, Roger Charlesworth, Brian Faria, Rui De mendonça fragata almeida, Inês Gilbert, Kimberly J. Jay, Paul Kapun, Martin Lotterhos, Katie E. Mérot, Claire Durmaz Mitchell, Esra Pascual, Marta Peichel, Catherine L. Rafajlović, Marina Westram, Anja M. Schaeffer, Stephen W. Johannesson, Kerstin Flatt, Thomas |
description |
Inversions are structural mutations that reverse the sequence of a chromosome segment and reduce the effective rate of recombination in the heterozygous state. They play a major role in adaptation, as well as in other evolutionary processes such as speciation. Although inversions have been studied since the 1920s, they remain difficult to investigate because the reduced recombination conferred by them strengthens the effects of drift and hitchhiking, which in turn can obscure signatures of selection. Nonetheless, numerous inversions have been found to be under selection. Given recent advances in population genetic theory and empirical study, here we review how different mechanisms of selection affect the evolution of inversions. A key difference between inversions and other mutations, such as single nucleotide variants, is that the fitness of an inversion may be affected by a larger number of frequently interacting processes. This considerably complicates the analysis of the causes underlying the evolution of inversions. We discuss the extent to which these mechanisms can be disentangled, and by which approach |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-12 2023-12-01T00:00:00Z 2024-02-14T10:53:45Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10451/62608 |
url |
http://hdl.handle.net/10451/62608 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Emma L. Berdan, Nicholas H. Barton, Roger Butlin, Brian Charlesworth, Rui Faria, Inês Fragata, Kimberly J. Gilbert, Paul Jay, Martin Kapun, Katie E. Lotterhos, Claire Mérot, Esra Durmaz Mitchell, Marta Pascual, Catherine L. Peichel, Marina Rafajlović, Anja M. Westram, Stephen W. Schaeffer, Kerstin Johannesson, Thomas Flatt, How chromosomal inversions reorient the evolutionary process, Journal of Evolutionary Biology, Volume 36, Issue 12, 1 December 2023, Pages 1761–1782, https://doi.org/10.1111/jeb.14242 10.1111/jeb.14242 |
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info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Wiley |
publisher.none.fl_str_mv |
Wiley |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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