Buerger's Disease (Thromboangiitis Obliterans): a Diagnostic Challenge
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.17/2981 |
Resumo: | Buerger's disease or Thromboangiitis obliterans is a segmental inflammatory disease that affects the vessels and nerves of the extremities. It usually affects men below 45 years old and correlates with tobacco, as a predisposing factor. The authors present the case of a 34-year-old male, with ulcers in the fingertips with progressive worsening: acrocyanosis, slow healing, necrosis and finally loss of substance. Dorsalis pedis and posterior tibial pulses were not palpable. Personal history of heavy smoking was (20 pack-years). The angiography revealed proximal occlusion of the left posterior tibial and interosseal arteries, with distal circulation by the anterior tibial artery. He was submitted to disarticulation of the second left toe and therapy with pentoxifyline and iloprost infusion, calcium antagonist, antiplatelet drugs, statin and low molecular weight heparin (later replaced by oral anticoagulation). Improvement was seen of active vascular lesions and pain symptoms. |
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Buerger's Disease (Thromboangiitis Obliterans): a Diagnostic ChallengeAdultAngiographyAspirinAtorvastatin CalciumCalcium Channel BlockersDrug Therapy, CombinationHeparin, Low-Molecular-WeightHeptanoic AcidsHumansHydroxymethylglutaryl-CoA Reductase InhibitorsIloprostMaleNifedipinePentoxifyllinePlatelet Aggregation InhibitorsPyrrolesSmoking CessationThromboangiitis ObliteransHCC MEDBuerger's disease or Thromboangiitis obliterans is a segmental inflammatory disease that affects the vessels and nerves of the extremities. It usually affects men below 45 years old and correlates with tobacco, as a predisposing factor. The authors present the case of a 34-year-old male, with ulcers in the fingertips with progressive worsening: acrocyanosis, slow healing, necrosis and finally loss of substance. Dorsalis pedis and posterior tibial pulses were not palpable. Personal history of heavy smoking was (20 pack-years). The angiography revealed proximal occlusion of the left posterior tibial and interosseal arteries, with distal circulation by the anterior tibial artery. He was submitted to disarticulation of the second left toe and therapy with pentoxifyline and iloprost infusion, calcium antagonist, antiplatelet drugs, statin and low molecular weight heparin (later replaced by oral anticoagulation). Improvement was seen of active vascular lesions and pain symptoms.BMJ Publishing GroupRepositório do Centro Hospitalar Universitário de Lisboa Central, EPEJorge, VCAraújo, ACNoronha, CPanarra, ARiso, NVaz Riscado, M2018-05-23T10:16:38Z2011-09-132011-09-13T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/2981engBMJ Case Rep. 2011 Sep 13;2011. pii: bcr0820114621.10.1136/bcr.08.2011.4621info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:40:38Zoai:repositorio.chlc.min-saude.pt:10400.17/2981Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:20:17.885492Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Buerger's Disease (Thromboangiitis Obliterans): a Diagnostic Challenge |
title |
Buerger's Disease (Thromboangiitis Obliterans): a Diagnostic Challenge |
spellingShingle |
Buerger's Disease (Thromboangiitis Obliterans): a Diagnostic Challenge Jorge, VC Adult Angiography Aspirin Atorvastatin Calcium Calcium Channel Blockers Drug Therapy, Combination Heparin, Low-Molecular-Weight Heptanoic Acids Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors Iloprost Male Nifedipine Pentoxifylline Platelet Aggregation Inhibitors Pyrroles Smoking Cessation Thromboangiitis Obliterans HCC MED |
title_short |
Buerger's Disease (Thromboangiitis Obliterans): a Diagnostic Challenge |
title_full |
Buerger's Disease (Thromboangiitis Obliterans): a Diagnostic Challenge |
title_fullStr |
Buerger's Disease (Thromboangiitis Obliterans): a Diagnostic Challenge |
title_full_unstemmed |
Buerger's Disease (Thromboangiitis Obliterans): a Diagnostic Challenge |
title_sort |
Buerger's Disease (Thromboangiitis Obliterans): a Diagnostic Challenge |
author |
Jorge, VC |
author_facet |
Jorge, VC Araújo, AC Noronha, C Panarra, A Riso, N Vaz Riscado, M |
author_role |
author |
author2 |
Araújo, AC Noronha, C Panarra, A Riso, N Vaz Riscado, M |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE |
dc.contributor.author.fl_str_mv |
Jorge, VC Araújo, AC Noronha, C Panarra, A Riso, N Vaz Riscado, M |
dc.subject.por.fl_str_mv |
Adult Angiography Aspirin Atorvastatin Calcium Calcium Channel Blockers Drug Therapy, Combination Heparin, Low-Molecular-Weight Heptanoic Acids Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors Iloprost Male Nifedipine Pentoxifylline Platelet Aggregation Inhibitors Pyrroles Smoking Cessation Thromboangiitis Obliterans HCC MED |
topic |
Adult Angiography Aspirin Atorvastatin Calcium Calcium Channel Blockers Drug Therapy, Combination Heparin, Low-Molecular-Weight Heptanoic Acids Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors Iloprost Male Nifedipine Pentoxifylline Platelet Aggregation Inhibitors Pyrroles Smoking Cessation Thromboangiitis Obliterans HCC MED |
description |
Buerger's disease or Thromboangiitis obliterans is a segmental inflammatory disease that affects the vessels and nerves of the extremities. It usually affects men below 45 years old and correlates with tobacco, as a predisposing factor. The authors present the case of a 34-year-old male, with ulcers in the fingertips with progressive worsening: acrocyanosis, slow healing, necrosis and finally loss of substance. Dorsalis pedis and posterior tibial pulses were not palpable. Personal history of heavy smoking was (20 pack-years). The angiography revealed proximal occlusion of the left posterior tibial and interosseal arteries, with distal circulation by the anterior tibial artery. He was submitted to disarticulation of the second left toe and therapy with pentoxifyline and iloprost infusion, calcium antagonist, antiplatelet drugs, statin and low molecular weight heparin (later replaced by oral anticoagulation). Improvement was seen of active vascular lesions and pain symptoms. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-09-13 2011-09-13T00:00:00Z 2018-05-23T10:16:38Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.17/2981 |
url |
http://hdl.handle.net/10400.17/2981 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
BMJ Case Rep. 2011 Sep 13;2011. pii: bcr0820114621. 10.1136/bcr.08.2011.4621 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
BMJ Publishing Group |
publisher.none.fl_str_mv |
BMJ Publishing Group |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799131298837561344 |