Impacto da coartação da aorta reparada no trabalho miocárdico ventricular esquerdo

Detalhes bibliográficos
Autor(a) principal: Timóteo, Ana Teresa
Data de Publicação: 2022
Outros Autores: Branco, Luísa Moura, Galrinho, Ana, Rio, Pedro, Sousa, Lídia, Ferreira, Rui Cruz
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/135836
Resumo: Aims: Myocardial strain analysis enables more precise assessment of cardiac performance but is relatively load dependent. New tools have been developed with afterload adjustment. Our objective was to assess myocardial work (MW) in patients with repaired aortic coarctation (rACo). Methods: Prospective study of consecutive patients with rACo who underwent a routine transthoracic echocardiogram in 2018 and 2019 at our center. Patients with significant aortic valve disease, pacemaker, or other congenital heart diseases (except for mild bicuspid aortic valve disease) were excluded. Global longitudinal strain with two dimensional speckle tracking analysis and MW were obtained (GWI:Global Work Index; GCW: Global Constructive Work; GWW: Global Wasted Work; GWE: Global Work Efficiency). Blood pressure was measured in the patient's right arm. Results: We included 42 patients in the analysis, mean age of 37±10 years, 38% males. In this group, 52% had hypertension and 64% had a concomitant bicuspid aortic valve. In comparison to previously published reference values, patients with rACo had significantly lower GWI (1807 vs. 1896 mmHg%) and GCW (2173 vs. 2232 mmHg%) (p<0.001), particularly in males. Systolic blood pressure is an independent predictor for GWI (β=0.432) and for GCW (β=0.534) and GLS an independent predictor of all MW parameters (β>0.594). Neither age nor gender were independent predictors. Conclusions: In patients with rACo, there are some signs of left ventricular dysfunction with a reduction in GCW and GWI and with preserved GWE, despite normal ejection fraction and strain.
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spelling Impacto da coartação da aorta reparada no trabalho miocárdico ventricular esquerdoImpact of repaired aortic coarctation in left ventricular myocardial workMyocardial workRepaired aortic coarctationStrainCardiology and Cardiovascular MedicineAims: Myocardial strain analysis enables more precise assessment of cardiac performance but is relatively load dependent. New tools have been developed with afterload adjustment. Our objective was to assess myocardial work (MW) in patients with repaired aortic coarctation (rACo). Methods: Prospective study of consecutive patients with rACo who underwent a routine transthoracic echocardiogram in 2018 and 2019 at our center. Patients with significant aortic valve disease, pacemaker, or other congenital heart diseases (except for mild bicuspid aortic valve disease) were excluded. Global longitudinal strain with two dimensional speckle tracking analysis and MW were obtained (GWI:Global Work Index; GCW: Global Constructive Work; GWW: Global Wasted Work; GWE: Global Work Efficiency). Blood pressure was measured in the patient's right arm. Results: We included 42 patients in the analysis, mean age of 37±10 years, 38% males. In this group, 52% had hypertension and 64% had a concomitant bicuspid aortic valve. In comparison to previously published reference values, patients with rACo had significantly lower GWI (1807 vs. 1896 mmHg%) and GCW (2173 vs. 2232 mmHg%) (p<0.001), particularly in males. Systolic blood pressure is an independent predictor for GWI (β=0.432) and for GCW (β=0.534) and GLS an independent predictor of all MW parameters (β>0.594). Neither age nor gender were independent predictors. Conclusions: In patients with rACo, there are some signs of left ventricular dysfunction with a reduction in GCW and GWI and with preserved GWE, despite normal ejection fraction and strain.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNTimóteo, Ana TeresaBranco, Luísa MouraGalrinho, AnaRio, PedroSousa, LídiaFerreira, Rui Cruz2022-04-04T22:38:03Z2022-042022-04-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/135836por0870-2551PURE: 42240665https://doi.org/10.1016/j.repc.2021.02.024info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:14:06Zoai:run.unl.pt:10362/135836Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:48:30.770152Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Impacto da coartação da aorta reparada no trabalho miocárdico ventricular esquerdo
Impact of repaired aortic coarctation in left ventricular myocardial work
title Impacto da coartação da aorta reparada no trabalho miocárdico ventricular esquerdo
spellingShingle Impacto da coartação da aorta reparada no trabalho miocárdico ventricular esquerdo
Timóteo, Ana Teresa
Myocardial work
Repaired aortic coarctation
Strain
Cardiology and Cardiovascular Medicine
title_short Impacto da coartação da aorta reparada no trabalho miocárdico ventricular esquerdo
title_full Impacto da coartação da aorta reparada no trabalho miocárdico ventricular esquerdo
title_fullStr Impacto da coartação da aorta reparada no trabalho miocárdico ventricular esquerdo
title_full_unstemmed Impacto da coartação da aorta reparada no trabalho miocárdico ventricular esquerdo
title_sort Impacto da coartação da aorta reparada no trabalho miocárdico ventricular esquerdo
author Timóteo, Ana Teresa
author_facet Timóteo, Ana Teresa
Branco, Luísa Moura
Galrinho, Ana
Rio, Pedro
Sousa, Lídia
Ferreira, Rui Cruz
author_role author
author2 Branco, Luísa Moura
Galrinho, Ana
Rio, Pedro
Sousa, Lídia
Ferreira, Rui Cruz
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Timóteo, Ana Teresa
Branco, Luísa Moura
Galrinho, Ana
Rio, Pedro
Sousa, Lídia
Ferreira, Rui Cruz
dc.subject.por.fl_str_mv Myocardial work
Repaired aortic coarctation
Strain
Cardiology and Cardiovascular Medicine
topic Myocardial work
Repaired aortic coarctation
Strain
Cardiology and Cardiovascular Medicine
description Aims: Myocardial strain analysis enables more precise assessment of cardiac performance but is relatively load dependent. New tools have been developed with afterload adjustment. Our objective was to assess myocardial work (MW) in patients with repaired aortic coarctation (rACo). Methods: Prospective study of consecutive patients with rACo who underwent a routine transthoracic echocardiogram in 2018 and 2019 at our center. Patients with significant aortic valve disease, pacemaker, or other congenital heart diseases (except for mild bicuspid aortic valve disease) were excluded. Global longitudinal strain with two dimensional speckle tracking analysis and MW were obtained (GWI:Global Work Index; GCW: Global Constructive Work; GWW: Global Wasted Work; GWE: Global Work Efficiency). Blood pressure was measured in the patient's right arm. Results: We included 42 patients in the analysis, mean age of 37±10 years, 38% males. In this group, 52% had hypertension and 64% had a concomitant bicuspid aortic valve. In comparison to previously published reference values, patients with rACo had significantly lower GWI (1807 vs. 1896 mmHg%) and GCW (2173 vs. 2232 mmHg%) (p<0.001), particularly in males. Systolic blood pressure is an independent predictor for GWI (β=0.432) and for GCW (β=0.534) and GLS an independent predictor of all MW parameters (β>0.594). Neither age nor gender were independent predictors. Conclusions: In patients with rACo, there are some signs of left ventricular dysfunction with a reduction in GCW and GWI and with preserved GWE, despite normal ejection fraction and strain.
publishDate 2022
dc.date.none.fl_str_mv 2022-04-04T22:38:03Z
2022-04
2022-04-01T00:00:00Z
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PURE: 42240665
https://doi.org/10.1016/j.repc.2021.02.024
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