SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118 |
Resumo: | Introduction: COVID-19 is caused by the coronavirus SARS-CoV-2. Ocular manifestations have been reported including conjunctivitis and retinal changes. Therefore, it is of the utmost importance to clarify eye involvement in COVID-19 in order to help with its diagnosis and to further prevent its transmission. The purpose of this review is to describe the structure and transmission of SARS-CoV-2, reported ocular findings and protection strategies for ophthalmologists.Material and Methods: Literature search on PubMed for relevant articles using the keywords ‘COVID-19’, ‘coronavirus’, and ‘SARS-CoV-2’ in conjunction with ‘ophthalmology’ and ‘eye’. Moreover, official recommendations of ophthalmological societies were reviewed.Results: Although the conjunctiva is directly exposed to extraocular pathogens, and the mucosa of the ocular surface and upper respiratory tract are connected by the nasolacrimal duct, the eye is rarely involved in human SARS-CoV-2 infection and the SARS-CoV-2 RNA positive rate by RT-PCR test in tears and conjunctival secretions from patients with COVID-19 is also extremely low.Discussion: The eye can be affected by SARS-CoV-2, which is supported by some reports of conjunctivitis and retinal changes, but its role in the spread of the disease is still unknown.Conclusion: Given the current scarce evidence, more research is needed to clarify the relationship between SARS-CoV-2 and the eye. |
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SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical PracticeSARS-COV-2 em Oftalmologia: Evidência Atual e Recomendações para a Prática ClínicaConjunctivitisCoronavirus InfectionsCOVID-19Eye DiseasesOphthalmologySARS-COV-2ConjuntiviteCOVID-19Infecções por CoronavírusOftalmologiaOftalmopatiasSARS-COV-2Introduction: COVID-19 is caused by the coronavirus SARS-CoV-2. Ocular manifestations have been reported including conjunctivitis and retinal changes. Therefore, it is of the utmost importance to clarify eye involvement in COVID-19 in order to help with its diagnosis and to further prevent its transmission. The purpose of this review is to describe the structure and transmission of SARS-CoV-2, reported ocular findings and protection strategies for ophthalmologists.Material and Methods: Literature search on PubMed for relevant articles using the keywords ‘COVID-19’, ‘coronavirus’, and ‘SARS-CoV-2’ in conjunction with ‘ophthalmology’ and ‘eye’. Moreover, official recommendations of ophthalmological societies were reviewed.Results: Although the conjunctiva is directly exposed to extraocular pathogens, and the mucosa of the ocular surface and upper respiratory tract are connected by the nasolacrimal duct, the eye is rarely involved in human SARS-CoV-2 infection and the SARS-CoV-2 RNA positive rate by RT-PCR test in tears and conjunctival secretions from patients with COVID-19 is also extremely low.Discussion: The eye can be affected by SARS-CoV-2, which is supported by some reports of conjunctivitis and retinal changes, but its role in the spread of the disease is still unknown.Conclusion: Given the current scarce evidence, more research is needed to clarify the relationship between SARS-CoV-2 and the eye.Introdução: COVID-19 é o nome atribuído à doença causada pelo novo coronavírus - SARS-CoV-2. Esta infeção rapidamente atingiu uma disseminação mundial, face ao aumento da globalização e adaptação do vírus a ambientes distintos. Foram descritas manifestações oftalmológicas em doentes com COVID-19, nomeadamente, conjuntivite e alterações retinianas. Assim, é fundamental esclarecer o envolvimento ocular na COVID-19, contribuindo para o seu diagnóstico precoce e limitando a sua transmissão. O objetivo desta revisão é descrever a estrutura e o modo de transmissão do SARS-CoV-2, assim como manifestações oculares reportadas e estratégias de proteção para oftalmologistas.Material e Métodos: Revisão dos artigos relevantes publicados na PubMed usando as palavras-chave ‘COVID-19’, ‘coronavirus’ e ‘SARS-CoV-2’ em associação com as palavras ‘ophthalmology’ e ‘eye’. Além disso, foi feita uma revisão das recomendações oficiais de várias sociedades oftalmológicas a nível mundial.Resultados: Apesar da conjuntiva estar diretamente exposta a patógenos exógenos, e da mucosa da superfície ocular e do trato respiratório superior estarem conectados pelo canal nasolacrimal, o olho raramente parece ser afetado pelo SARS-CoV-2. A infeção por SARS-CoV-2 e a taxa de positividade para a pesquisa do RNA do SARS-CoV-2 pelo teste de RT-PCR em lágrimas e secreções conjuntivais de pacientes com COVID-19 também são extremamente baixas.Discussão: O olho pode ser afetado pelo SARS-CoV-2, dada a descrição de casos de conjuntivite e alterações retinianas, mas o seu papel na disseminação da doença ainda é desconhecido.Conclusão: Dada a escassa evidência atual, são necessários mais estudos para esclarecer a relação entre o SARS-CoV-2 e o globo ocular.Ordem dos Médicos2020-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118oai:ojs.www.actamedicaportuguesa.com:article/14118Acta Médica Portuguesa; Vol. 33 No. 9 (2020): September; 593-600Acta Médica Portuguesa; Vol. 33 N.º 9 (2020): Setembro; 593-6001646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/6013https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/6088https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12594https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12595https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12695https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12696https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12697https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12705Direitos de Autor (c) 2020 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessTorres-Costa, SóniaLima-Fontes, MárioFalcão-Reis, FernandoFalcão, Manuel2022-12-20T11:07:07Zoai:ojs.www.actamedicaportuguesa.com:article/14118Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:20:26.461600Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice SARS-COV-2 em Oftalmologia: Evidência Atual e Recomendações para a Prática Clínica |
title |
SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice |
spellingShingle |
SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice Torres-Costa, Sónia Conjunctivitis Coronavirus Infections COVID-19 Eye Diseases Ophthalmology SARS-COV-2 Conjuntivite COVID-19 Infecções por Coronavírus Oftalmologia Oftalmopatias SARS-COV-2 |
title_short |
SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice |
title_full |
SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice |
title_fullStr |
SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice |
title_full_unstemmed |
SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice |
title_sort |
SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice |
author |
Torres-Costa, Sónia |
author_facet |
Torres-Costa, Sónia Lima-Fontes, Mário Falcão-Reis, Fernando Falcão, Manuel |
author_role |
author |
author2 |
Lima-Fontes, Mário Falcão-Reis, Fernando Falcão, Manuel |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Torres-Costa, Sónia Lima-Fontes, Mário Falcão-Reis, Fernando Falcão, Manuel |
dc.subject.por.fl_str_mv |
Conjunctivitis Coronavirus Infections COVID-19 Eye Diseases Ophthalmology SARS-COV-2 Conjuntivite COVID-19 Infecções por Coronavírus Oftalmologia Oftalmopatias SARS-COV-2 |
topic |
Conjunctivitis Coronavirus Infections COVID-19 Eye Diseases Ophthalmology SARS-COV-2 Conjuntivite COVID-19 Infecções por Coronavírus Oftalmologia Oftalmopatias SARS-COV-2 |
description |
Introduction: COVID-19 is caused by the coronavirus SARS-CoV-2. Ocular manifestations have been reported including conjunctivitis and retinal changes. Therefore, it is of the utmost importance to clarify eye involvement in COVID-19 in order to help with its diagnosis and to further prevent its transmission. The purpose of this review is to describe the structure and transmission of SARS-CoV-2, reported ocular findings and protection strategies for ophthalmologists.Material and Methods: Literature search on PubMed for relevant articles using the keywords ‘COVID-19’, ‘coronavirus’, and ‘SARS-CoV-2’ in conjunction with ‘ophthalmology’ and ‘eye’. Moreover, official recommendations of ophthalmological societies were reviewed.Results: Although the conjunctiva is directly exposed to extraocular pathogens, and the mucosa of the ocular surface and upper respiratory tract are connected by the nasolacrimal duct, the eye is rarely involved in human SARS-CoV-2 infection and the SARS-CoV-2 RNA positive rate by RT-PCR test in tears and conjunctival secretions from patients with COVID-19 is also extremely low.Discussion: The eye can be affected by SARS-CoV-2, which is supported by some reports of conjunctivitis and retinal changes, but its role in the spread of the disease is still unknown.Conclusion: Given the current scarce evidence, more research is needed to clarify the relationship between SARS-CoV-2 and the eye. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-09-01 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118 oai:ojs.www.actamedicaportuguesa.com:article/14118 |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118 |
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oai:ojs.www.actamedicaportuguesa.com:article/14118 |
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eng |
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eng |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/6013 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/6088 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12594 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12595 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12695 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12696 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12697 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12705 |
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Direitos de Autor (c) 2020 Acta Médica Portuguesa info:eu-repo/semantics/openAccess |
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Direitos de Autor (c) 2020 Acta Médica Portuguesa |
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Ordem dos Médicos |
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Ordem dos Médicos |
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Acta Médica Portuguesa; Vol. 33 No. 9 (2020): September; 593-600 Acta Médica Portuguesa; Vol. 33 N.º 9 (2020): Setembro; 593-600 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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