SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice

Detalhes bibliográficos
Autor(a) principal: Torres-Costa, Sónia
Data de Publicação: 2020
Outros Autores: Lima-Fontes, Mário, Falcão-Reis, Fernando, Falcão, Manuel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118
Resumo: Introduction: COVID-19 is caused by the coronavirus SARS-CoV-2. Ocular manifestations have been reported including conjunctivitis and retinal changes. Therefore, it is of the utmost importance to clarify eye involvement in COVID-19 in order to help with its diagnosis and to further prevent its transmission. The purpose of this review is to describe the structure and transmission of SARS-CoV-2, reported ocular findings and protection strategies for ophthalmologists.Material and Methods: Literature search on PubMed for relevant articles using the keywords ‘COVID-19’, ‘coronavirus’, and ‘SARS-CoV-2’ in conjunction with ‘ophthalmology’ and ‘eye’. Moreover, official recommendations of ophthalmological societies were reviewed.Results: Although the conjunctiva is directly exposed to extraocular pathogens, and the mucosa of the ocular surface and upper respiratory tract are connected by the nasolacrimal duct, the eye is rarely involved in human SARS-CoV-2 infection and the SARS-CoV-2 RNA positive rate by RT-PCR test in tears and conjunctival secretions from patients with COVID-19 is also extremely low.Discussion: The eye can be affected by SARS-CoV-2, which is supported by some reports of conjunctivitis and retinal changes, but its role in the spread of the disease is still unknown.Conclusion: Given the current scarce evidence, more research is needed to clarify the relationship between SARS-CoV-2 and the eye.
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spelling SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical PracticeSARS-COV-2 em Oftalmologia: Evidência Atual e Recomendações para a Prática ClínicaConjunctivitisCoronavirus InfectionsCOVID-19Eye DiseasesOphthalmologySARS-COV-2ConjuntiviteCOVID-19Infecções por CoronavírusOftalmologiaOftalmopatiasSARS-COV-2Introduction: COVID-19 is caused by the coronavirus SARS-CoV-2. Ocular manifestations have been reported including conjunctivitis and retinal changes. Therefore, it is of the utmost importance to clarify eye involvement in COVID-19 in order to help with its diagnosis and to further prevent its transmission. The purpose of this review is to describe the structure and transmission of SARS-CoV-2, reported ocular findings and protection strategies for ophthalmologists.Material and Methods: Literature search on PubMed for relevant articles using the keywords ‘COVID-19’, ‘coronavirus’, and ‘SARS-CoV-2’ in conjunction with ‘ophthalmology’ and ‘eye’. Moreover, official recommendations of ophthalmological societies were reviewed.Results: Although the conjunctiva is directly exposed to extraocular pathogens, and the mucosa of the ocular surface and upper respiratory tract are connected by the nasolacrimal duct, the eye is rarely involved in human SARS-CoV-2 infection and the SARS-CoV-2 RNA positive rate by RT-PCR test in tears and conjunctival secretions from patients with COVID-19 is also extremely low.Discussion: The eye can be affected by SARS-CoV-2, which is supported by some reports of conjunctivitis and retinal changes, but its role in the spread of the disease is still unknown.Conclusion: Given the current scarce evidence, more research is needed to clarify the relationship between SARS-CoV-2 and the eye.Introdução: COVID-19 é o nome atribuído à doença causada pelo novo coronavírus - SARS-CoV-2. Esta infeção rapidamente atingiu uma disseminação mundial, face ao aumento da globalização e adaptação do vírus a ambientes distintos. Foram descritas manifestações oftalmológicas em doentes com COVID-19, nomeadamente, conjuntivite e alterações retinianas. Assim, é fundamental esclarecer o envolvimento ocular na COVID-19, contribuindo para o seu diagnóstico precoce e limitando a sua transmissão. O objetivo desta revisão é descrever a estrutura e o modo de transmissão do SARS-CoV-2, assim como manifestações oculares reportadas e estratégias de proteção para oftalmologistas.Material e Métodos: Revisão dos artigos relevantes publicados na PubMed usando as palavras-chave ‘COVID-19’, ‘coronavirus’ e ‘SARS-CoV-2’ em associação com as palavras ‘ophthalmology’ e ‘eye’. Além disso, foi feita uma revisão das recomendações oficiais de várias sociedades oftalmológicas a nível mundial.Resultados: Apesar da conjuntiva estar diretamente exposta a patógenos exógenos, e da mucosa da superfície ocular e do trato respiratório superior estarem conectados pelo canal nasolacrimal, o olho raramente parece ser afetado pelo SARS-CoV-2. A infeção por SARS-CoV-2 e a taxa de positividade para a pesquisa do RNA do SARS-CoV-2 pelo teste de RT-PCR em lágrimas e secreções conjuntivais de pacientes com COVID-19 também são extremamente baixas.Discussão: O olho pode ser afetado pelo SARS-CoV-2, dada a descrição de casos de conjuntivite e alterações retinianas, mas o seu papel na disseminação da doença ainda é desconhecido.Conclusão: Dada a escassa evidência atual, são necessários mais estudos para esclarecer a relação entre o SARS-CoV-2 e o globo ocular.Ordem dos Médicos2020-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118oai:ojs.www.actamedicaportuguesa.com:article/14118Acta Médica Portuguesa; Vol. 33 No. 9 (2020): September; 593-600Acta Médica Portuguesa; Vol. 33 N.º 9 (2020): Setembro; 593-6001646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/6013https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/6088https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12594https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12595https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12695https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12696https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12697https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12705Direitos de Autor (c) 2020 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessTorres-Costa, SóniaLima-Fontes, MárioFalcão-Reis, FernandoFalcão, Manuel2022-12-20T11:07:07Zoai:ojs.www.actamedicaportuguesa.com:article/14118Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:20:26.461600Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice
SARS-COV-2 em Oftalmologia: Evidência Atual e Recomendações para a Prática Clínica
title SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice
spellingShingle SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice
Torres-Costa, Sónia
Conjunctivitis
Coronavirus Infections
COVID-19
Eye Diseases
Ophthalmology
SARS-COV-2
Conjuntivite
COVID-19
Infecções por Coronavírus
Oftalmologia
Oftalmopatias
SARS-COV-2
title_short SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice
title_full SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice
title_fullStr SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice
title_full_unstemmed SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice
title_sort SARS-COV-2 in Ophthalmology: Current Evidence and Standards for Clinical Practice
author Torres-Costa, Sónia
author_facet Torres-Costa, Sónia
Lima-Fontes, Mário
Falcão-Reis, Fernando
Falcão, Manuel
author_role author
author2 Lima-Fontes, Mário
Falcão-Reis, Fernando
Falcão, Manuel
author2_role author
author
author
dc.contributor.author.fl_str_mv Torres-Costa, Sónia
Lima-Fontes, Mário
Falcão-Reis, Fernando
Falcão, Manuel
dc.subject.por.fl_str_mv Conjunctivitis
Coronavirus Infections
COVID-19
Eye Diseases
Ophthalmology
SARS-COV-2
Conjuntivite
COVID-19
Infecções por Coronavírus
Oftalmologia
Oftalmopatias
SARS-COV-2
topic Conjunctivitis
Coronavirus Infections
COVID-19
Eye Diseases
Ophthalmology
SARS-COV-2
Conjuntivite
COVID-19
Infecções por Coronavírus
Oftalmologia
Oftalmopatias
SARS-COV-2
description Introduction: COVID-19 is caused by the coronavirus SARS-CoV-2. Ocular manifestations have been reported including conjunctivitis and retinal changes. Therefore, it is of the utmost importance to clarify eye involvement in COVID-19 in order to help with its diagnosis and to further prevent its transmission. The purpose of this review is to describe the structure and transmission of SARS-CoV-2, reported ocular findings and protection strategies for ophthalmologists.Material and Methods: Literature search on PubMed for relevant articles using the keywords ‘COVID-19’, ‘coronavirus’, and ‘SARS-CoV-2’ in conjunction with ‘ophthalmology’ and ‘eye’. Moreover, official recommendations of ophthalmological societies were reviewed.Results: Although the conjunctiva is directly exposed to extraocular pathogens, and the mucosa of the ocular surface and upper respiratory tract are connected by the nasolacrimal duct, the eye is rarely involved in human SARS-CoV-2 infection and the SARS-CoV-2 RNA positive rate by RT-PCR test in tears and conjunctival secretions from patients with COVID-19 is also extremely low.Discussion: The eye can be affected by SARS-CoV-2, which is supported by some reports of conjunctivitis and retinal changes, but its role in the spread of the disease is still unknown.Conclusion: Given the current scarce evidence, more research is needed to clarify the relationship between SARS-CoV-2 and the eye.
publishDate 2020
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/6088
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12594
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12595
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12695
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12696
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12697
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/14118/12705
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2020 Acta Médica Portuguesa
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 33 No. 9 (2020): September; 593-600
Acta Médica Portuguesa; Vol. 33 N.º 9 (2020): Setembro; 593-600
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0870-399X
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