Infeções urinárias na gravidez
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302017000400004 |
Resumo: | Overview and Aims: Urinary tract infections (UTI) are frequent in pregnancy and are associated with increased preterm delivery and low birth weight. Asymptomatic bacteriuria (ABU) is the most common clinical entity and in the absence of treatment it can progress to pyelonephritis in 25% to 30% of the cases. The culture of a urine specimen is the gold standard for the diagnosis of UTI, being Escherichia coli the most common agent. The aim of this study is 1) to identify which are the main microbial agents of the urine cultures in a pregnant population, 2) to observe the agents' antibiotic resistance and sensitivity, 3) to investigate which are the best antimicrobials for the treatment of an UTI in pregnant women, and 4) to compare with a similar study conducted at the same hospital between 2005 and 2006 in order to analyze the evolution of the antimicrobial resistances pattern. Study design: Retrospective observational study. Population: 305 cases with positive urine cultures obtained in the obstetrics outpatient clinic of a tertiary care hospital, between January 2014 and December 2015. Results: E. coli was isolated in 48,9% of cases. Streptococcus agalactiae was identified in 18,4%, Klebsiella pneumoniae in 10,1% and Proteus mirabilis in 8,5%. The global antimicrobial resistance profile was: ampicillin 50%, nitrofurantoin 24%, cotrimoxazole 17%, cefalotin 11%, amoxicilin+clavulanate and gentamycin both 6%, cefuroxime 3%, ceftazidime ceftriaxone and piperacilin-tazobactam 0%. Conclusions: In our population, the most frequent agent was E. coli. Cefuroxime is a good choice as a first-line agent for empiric treatment. Ampicillin and cotrimoxazole presented both high global and E. coli specific resistance rates. Comparatively to 2005 and 2006, the resistances have increased for nitrofurantoin and decreased for amoxicilin+clavulanate |
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Infeções urinárias na gravidezUrinary tract infectionsPregnancyMicrobial sensitivity testsDrug resistanceMicrobialOverview and Aims: Urinary tract infections (UTI) are frequent in pregnancy and are associated with increased preterm delivery and low birth weight. Asymptomatic bacteriuria (ABU) is the most common clinical entity and in the absence of treatment it can progress to pyelonephritis in 25% to 30% of the cases. The culture of a urine specimen is the gold standard for the diagnosis of UTI, being Escherichia coli the most common agent. The aim of this study is 1) to identify which are the main microbial agents of the urine cultures in a pregnant population, 2) to observe the agents' antibiotic resistance and sensitivity, 3) to investigate which are the best antimicrobials for the treatment of an UTI in pregnant women, and 4) to compare with a similar study conducted at the same hospital between 2005 and 2006 in order to analyze the evolution of the antimicrobial resistances pattern. Study design: Retrospective observational study. Population: 305 cases with positive urine cultures obtained in the obstetrics outpatient clinic of a tertiary care hospital, between January 2014 and December 2015. Results: E. coli was isolated in 48,9% of cases. Streptococcus agalactiae was identified in 18,4%, Klebsiella pneumoniae in 10,1% and Proteus mirabilis in 8,5%. The global antimicrobial resistance profile was: ampicillin 50%, nitrofurantoin 24%, cotrimoxazole 17%, cefalotin 11%, amoxicilin+clavulanate and gentamycin both 6%, cefuroxime 3%, ceftazidime ceftriaxone and piperacilin-tazobactam 0%. Conclusions: In our population, the most frequent agent was E. coli. Cefuroxime is a good choice as a first-line agent for empiric treatment. Ampicillin and cotrimoxazole presented both high global and E. coli specific resistance rates. Comparatively to 2005 and 2006, the resistances have increased for nitrofurantoin and decreased for amoxicilin+clavulanateEuromédice, Edições Médicas Lda.2017-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articletext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302017000400004Acta Obstétrica e Ginecológica Portuguesa v.11 n.4 2017reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302017000400004Gomes,InêsMetello,JoséFreitas,BrunoDiogo,Joséinfo:eu-repo/semantics/openAccess2024-02-06T17:21:39Zoai:scielo:S1646-58302017000400004Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:28:36.888456Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Infeções urinárias na gravidez |
title |
Infeções urinárias na gravidez |
spellingShingle |
Infeções urinárias na gravidez Gomes,Inês Urinary tract infections Pregnancy Microbial sensitivity tests Drug resistance Microbial |
title_short |
Infeções urinárias na gravidez |
title_full |
Infeções urinárias na gravidez |
title_fullStr |
Infeções urinárias na gravidez |
title_full_unstemmed |
Infeções urinárias na gravidez |
title_sort |
Infeções urinárias na gravidez |
author |
Gomes,Inês |
author_facet |
Gomes,Inês Metello,José Freitas,Bruno Diogo,José |
author_role |
author |
author2 |
Metello,José Freitas,Bruno Diogo,José |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Gomes,Inês Metello,José Freitas,Bruno Diogo,José |
dc.subject.por.fl_str_mv |
Urinary tract infections Pregnancy Microbial sensitivity tests Drug resistance Microbial |
topic |
Urinary tract infections Pregnancy Microbial sensitivity tests Drug resistance Microbial |
description |
Overview and Aims: Urinary tract infections (UTI) are frequent in pregnancy and are associated with increased preterm delivery and low birth weight. Asymptomatic bacteriuria (ABU) is the most common clinical entity and in the absence of treatment it can progress to pyelonephritis in 25% to 30% of the cases. The culture of a urine specimen is the gold standard for the diagnosis of UTI, being Escherichia coli the most common agent. The aim of this study is 1) to identify which are the main microbial agents of the urine cultures in a pregnant population, 2) to observe the agents' antibiotic resistance and sensitivity, 3) to investigate which are the best antimicrobials for the treatment of an UTI in pregnant women, and 4) to compare with a similar study conducted at the same hospital between 2005 and 2006 in order to analyze the evolution of the antimicrobial resistances pattern. Study design: Retrospective observational study. Population: 305 cases with positive urine cultures obtained in the obstetrics outpatient clinic of a tertiary care hospital, between January 2014 and December 2015. Results: E. coli was isolated in 48,9% of cases. Streptococcus agalactiae was identified in 18,4%, Klebsiella pneumoniae in 10,1% and Proteus mirabilis in 8,5%. The global antimicrobial resistance profile was: ampicillin 50%, nitrofurantoin 24%, cotrimoxazole 17%, cefalotin 11%, amoxicilin+clavulanate and gentamycin both 6%, cefuroxime 3%, ceftazidime ceftriaxone and piperacilin-tazobactam 0%. Conclusions: In our population, the most frequent agent was E. coli. Cefuroxime is a good choice as a first-line agent for empiric treatment. Ampicillin and cotrimoxazole presented both high global and E. coli specific resistance rates. Comparatively to 2005 and 2006, the resistances have increased for nitrofurantoin and decreased for amoxicilin+clavulanate |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-10-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302017000400004 |
url |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302017000400004 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-58302017000400004 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Euromédice, Edições Médicas Lda. |
publisher.none.fl_str_mv |
Euromédice, Edições Médicas Lda. |
dc.source.none.fl_str_mv |
Acta Obstétrica e Ginecológica Portuguesa v.11 n.4 2017 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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