Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/107522 https://doi.org/10.1136/bmjopen-2017-019542 |
Resumo: | Introduction Polypharmacy is commonly defined as the simultaneous taking of five or more drugs. Deprescribing is the process of tapering or stopping medications with the aim of improving patient outcomes and optimising current therapy, and there are several tools aiming at identifying potentially inappropriate medications, especially in the elderly. The direct involvement of patients and their caregivers in the choice and administration of drugs has long been known to be very important, but it is not usually applied. The aim of this study is to assess the knowledge of older adults about deprescription, the effect on willingness to have regular medications deprescribed and its quality-of-life outcome. Methods and analysis This study protocol comprises three phases. The first two phases will be nationwide and aim to evaluate the prevalence and patterns of polypharmacy and assess the barriers and facilitators of deprescribing perceived by older adults, as well as their willingness to have regular medications deprescribed and to self-medicate. The third and last phase will be a nonpharmacological randomised clinical study to measure older patients’ acceptance to have regular medications deprescribed and related quality of life. Ethics and dissemination The study will be conducted in accordance with the principles expressed in the Declaration of Helsinki. It has been approved by the Ethics Committee of the University of Beira Interior and Portuguese National Data Protection Commission. Study results will be published in peer-reviewed journals and presented at national and international conferences. In short, no action will be taken without written consent from patients and doctors. Trial registration number >NCT03283735. |
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Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocoldeprescribingelderlypolypharmacyquality of lifewillingnessAgedCross-Sectional StudiesHealth Knowledge, Attitudes, PracticeHumansInappropriate PrescribingMulticenter Studies as TopicObservational Studies as TopicPortugalPrimary Health CareQuality of LifeRandomized Controlled Trials as TopicDeprescriptionsPolypharmacyIntroduction Polypharmacy is commonly defined as the simultaneous taking of five or more drugs. Deprescribing is the process of tapering or stopping medications with the aim of improving patient outcomes and optimising current therapy, and there are several tools aiming at identifying potentially inappropriate medications, especially in the elderly. The direct involvement of patients and their caregivers in the choice and administration of drugs has long been known to be very important, but it is not usually applied. The aim of this study is to assess the knowledge of older adults about deprescription, the effect on willingness to have regular medications deprescribed and its quality-of-life outcome. Methods and analysis This study protocol comprises three phases. The first two phases will be nationwide and aim to evaluate the prevalence and patterns of polypharmacy and assess the barriers and facilitators of deprescribing perceived by older adults, as well as their willingness to have regular medications deprescribed and to self-medicate. The third and last phase will be a nonpharmacological randomised clinical study to measure older patients’ acceptance to have regular medications deprescribed and related quality of life. Ethics and dissemination The study will be conducted in accordance with the principles expressed in the Declaration of Helsinki. It has been approved by the Ethics Committee of the University of Beira Interior and Portuguese National Data Protection Commission. Study results will be published in peer-reviewed journals and presented at national and international conferences. In short, no action will be taken without written consent from patients and doctors. Trial registration number >NCT03283735.BMJ Publishing Group2018-07-17info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/107522http://hdl.handle.net/10316/107522https://doi.org/10.1136/bmjopen-2017-019542eng2044-60552044-6055Simões, Pedro AugustoSantiago, Luiz MiguelSimões, José Augustoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-18T11:11:20Zoai:estudogeral.uc.pt:10316/107522Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:23:52.156560Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol |
title |
Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol |
spellingShingle |
Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol Simões, Pedro Augusto deprescribing elderly polypharmacy quality of life willingness Aged Cross-Sectional Studies Health Knowledge, Attitudes, Practice Humans Inappropriate Prescribing Multicenter Studies as Topic Observational Studies as Topic Portugal Primary Health Care Quality of Life Randomized Controlled Trials as Topic Deprescriptions Polypharmacy |
title_short |
Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol |
title_full |
Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol |
title_fullStr |
Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol |
title_full_unstemmed |
Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol |
title_sort |
Deprescribing in primary care in Portugal (DePil17-20): a three-phase observational and experimental study protocol |
author |
Simões, Pedro Augusto |
author_facet |
Simões, Pedro Augusto Santiago, Luiz Miguel Simões, José Augusto |
author_role |
author |
author2 |
Santiago, Luiz Miguel Simões, José Augusto |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Simões, Pedro Augusto Santiago, Luiz Miguel Simões, José Augusto |
dc.subject.por.fl_str_mv |
deprescribing elderly polypharmacy quality of life willingness Aged Cross-Sectional Studies Health Knowledge, Attitudes, Practice Humans Inappropriate Prescribing Multicenter Studies as Topic Observational Studies as Topic Portugal Primary Health Care Quality of Life Randomized Controlled Trials as Topic Deprescriptions Polypharmacy |
topic |
deprescribing elderly polypharmacy quality of life willingness Aged Cross-Sectional Studies Health Knowledge, Attitudes, Practice Humans Inappropriate Prescribing Multicenter Studies as Topic Observational Studies as Topic Portugal Primary Health Care Quality of Life Randomized Controlled Trials as Topic Deprescriptions Polypharmacy |
description |
Introduction Polypharmacy is commonly defined as the simultaneous taking of five or more drugs. Deprescribing is the process of tapering or stopping medications with the aim of improving patient outcomes and optimising current therapy, and there are several tools aiming at identifying potentially inappropriate medications, especially in the elderly. The direct involvement of patients and their caregivers in the choice and administration of drugs has long been known to be very important, but it is not usually applied. The aim of this study is to assess the knowledge of older adults about deprescription, the effect on willingness to have regular medications deprescribed and its quality-of-life outcome. Methods and analysis This study protocol comprises three phases. The first two phases will be nationwide and aim to evaluate the prevalence and patterns of polypharmacy and assess the barriers and facilitators of deprescribing perceived by older adults, as well as their willingness to have regular medications deprescribed and to self-medicate. The third and last phase will be a nonpharmacological randomised clinical study to measure older patients’ acceptance to have regular medications deprescribed and related quality of life. Ethics and dissemination The study will be conducted in accordance with the principles expressed in the Declaration of Helsinki. It has been approved by the Ethics Committee of the University of Beira Interior and Portuguese National Data Protection Commission. Study results will be published in peer-reviewed journals and presented at national and international conferences. In short, no action will be taken without written consent from patients and doctors. Trial registration number >NCT03283735. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-07-17 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/107522 http://hdl.handle.net/10316/107522 https://doi.org/10.1136/bmjopen-2017-019542 |
url |
http://hdl.handle.net/10316/107522 https://doi.org/10.1136/bmjopen-2017-019542 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2044-6055 2044-6055 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
BMJ Publishing Group |
publisher.none.fl_str_mv |
BMJ Publishing Group |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799134125060259840 |