Updating predictors of endoscopic recurrence after ileocolic resection for Crohn disease
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/51542 |
Resumo: | Background/Aims: Identifying predictors of endoscopic recurrence (ER) has become very important to guide the decision of postoperative strategy. This study aimed to determine the rate of endoscopic recurrence until 12 months after ileocolic resection for Crohn disease (CD) in a cohort and identify its possible predictors. Materials and Methods: We conducted a retrospective single-center study that included patients with CD who underwent ileocolic resection between 2003 and 2014. ER was defined according to the Rutgeerts' score, defined as i2, i3, or i4 at ileocolonoscopy that was performed 6-12 months after surgery. The patients were classified into two groups according to the Rutgeerts' score: non-ER (Rutgeerts i0/i1) and ER (Rutgeerts >= i2). Multivariate logistic regression analysis was performed, including significant variables on univariable analysis, to identify ER predictors. Results: Forty-two patients were included. The mean period of the first postoperative colonoscopy was 9 months, and ER was observed in 25 patients (59.5%). The perianal disease and shorter duration of CD were the only ER predictors (p=0.024; OR, 8.36; 95% CI, 1.329-52.642 and p=0.039; OR, 0.965; 95% CI, 0.933-0.998, respectively). Conclusion: Endoscopic recurrence affects almost two-thirds of patients with CD after ileocolic resection, with perianal involvement and a shorter duration of disease being significant risk factors. These factors may indicate a more aggressive disease associated with rapid progression and support the need of intensive early treatment to improve patients' outcomes. |
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Updating predictors of endoscopic recurrence after ileocolic resection for Crohn diseaseCrohn diseaseEndoscopySurgeryCiências Médicas::Medicina ClínicaScience & TechnologyBackground/Aims: Identifying predictors of endoscopic recurrence (ER) has become very important to guide the decision of postoperative strategy. This study aimed to determine the rate of endoscopic recurrence until 12 months after ileocolic resection for Crohn disease (CD) in a cohort and identify its possible predictors. Materials and Methods: We conducted a retrospective single-center study that included patients with CD who underwent ileocolic resection between 2003 and 2014. ER was defined according to the Rutgeerts' score, defined as i2, i3, or i4 at ileocolonoscopy that was performed 6-12 months after surgery. The patients were classified into two groups according to the Rutgeerts' score: non-ER (Rutgeerts i0/i1) and ER (Rutgeerts >= i2). Multivariate logistic regression analysis was performed, including significant variables on univariable analysis, to identify ER predictors. Results: Forty-two patients were included. The mean period of the first postoperative colonoscopy was 9 months, and ER was observed in 25 patients (59.5%). The perianal disease and shorter duration of CD were the only ER predictors (p=0.024; OR, 8.36; 95% CI, 1.329-52.642 and p=0.039; OR, 0.965; 95% CI, 0.933-0.998, respectively). Conclusion: Endoscopic recurrence affects almost two-thirds of patients with CD after ileocolic resection, with perianal involvement and a shorter duration of disease being significant risk factors. These factors may indicate a more aggressive disease associated with rapid progression and support the need of intensive early treatment to improve patients' outcomes.info:eu-repo/semantics/publishedVersionTurkish Society of GastroenterologyUniversidade do MinhoMonteiro, SaraGonçalves, Tiago CúrdiaCarvalho, Pedro BoalMoreira, Maria JoãoCotter, José Almeida Berkeley2017-07-012017-07-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/51542engMonteiro, S., Gonçalves, T. C., Carvalho, P. B., Moreira, M. J., & Cotter, J. (2017). Updating predictors of endoscopic recurrence after ileocolic resection for Crohn disease. Turk J Gastroenterol, 28, 260-51300-49482148-560710.5152/tjg.2017.1672128594329http://www.turkjgastroenterol.org/eng/makale/5056/300/Full-Textinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-11T06:37:17Zoai:repositorium.sdum.uminho.pt:1822/51542Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-11T06:37:17Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Updating predictors of endoscopic recurrence after ileocolic resection for Crohn disease |
title |
Updating predictors of endoscopic recurrence after ileocolic resection for Crohn disease |
spellingShingle |
Updating predictors of endoscopic recurrence after ileocolic resection for Crohn disease Monteiro, Sara Crohn disease Endoscopy Surgery Ciências Médicas::Medicina Clínica Science & Technology |
title_short |
Updating predictors of endoscopic recurrence after ileocolic resection for Crohn disease |
title_full |
Updating predictors of endoscopic recurrence after ileocolic resection for Crohn disease |
title_fullStr |
Updating predictors of endoscopic recurrence after ileocolic resection for Crohn disease |
title_full_unstemmed |
Updating predictors of endoscopic recurrence after ileocolic resection for Crohn disease |
title_sort |
Updating predictors of endoscopic recurrence after ileocolic resection for Crohn disease |
author |
Monteiro, Sara |
author_facet |
Monteiro, Sara Gonçalves, Tiago Cúrdia Carvalho, Pedro Boal Moreira, Maria João Cotter, José Almeida Berkeley |
author_role |
author |
author2 |
Gonçalves, Tiago Cúrdia Carvalho, Pedro Boal Moreira, Maria João Cotter, José Almeida Berkeley |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Monteiro, Sara Gonçalves, Tiago Cúrdia Carvalho, Pedro Boal Moreira, Maria João Cotter, José Almeida Berkeley |
dc.subject.por.fl_str_mv |
Crohn disease Endoscopy Surgery Ciências Médicas::Medicina Clínica Science & Technology |
topic |
Crohn disease Endoscopy Surgery Ciências Médicas::Medicina Clínica Science & Technology |
description |
Background/Aims: Identifying predictors of endoscopic recurrence (ER) has become very important to guide the decision of postoperative strategy. This study aimed to determine the rate of endoscopic recurrence until 12 months after ileocolic resection for Crohn disease (CD) in a cohort and identify its possible predictors. Materials and Methods: We conducted a retrospective single-center study that included patients with CD who underwent ileocolic resection between 2003 and 2014. ER was defined according to the Rutgeerts' score, defined as i2, i3, or i4 at ileocolonoscopy that was performed 6-12 months after surgery. The patients were classified into two groups according to the Rutgeerts' score: non-ER (Rutgeerts i0/i1) and ER (Rutgeerts >= i2). Multivariate logistic regression analysis was performed, including significant variables on univariable analysis, to identify ER predictors. Results: Forty-two patients were included. The mean period of the first postoperative colonoscopy was 9 months, and ER was observed in 25 patients (59.5%). The perianal disease and shorter duration of CD were the only ER predictors (p=0.024; OR, 8.36; 95% CI, 1.329-52.642 and p=0.039; OR, 0.965; 95% CI, 0.933-0.998, respectively). Conclusion: Endoscopic recurrence affects almost two-thirds of patients with CD after ileocolic resection, with perianal involvement and a shorter duration of disease being significant risk factors. These factors may indicate a more aggressive disease associated with rapid progression and support the need of intensive early treatment to improve patients' outcomes. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-07-01 2017-07-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/51542 |
url |
http://hdl.handle.net/1822/51542 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Monteiro, S., Gonçalves, T. C., Carvalho, P. B., Moreira, M. J., & Cotter, J. (2017). Updating predictors of endoscopic recurrence after ileocolic resection for Crohn disease. Turk J Gastroenterol, 28, 260-5 1300-4948 2148-5607 10.5152/tjg.2017.16721 28594329 http://www.turkjgastroenterol.org/eng/makale/5056/300/Full-Text |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Turkish Society of Gastroenterology |
publisher.none.fl_str_mv |
Turkish Society of Gastroenterology |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
mluisa.alvim@gmail.com |
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1817545034396860416 |