Antioxidant,antimicrobial and toxicological properties of Schinus molle L. essential oils

Detalhes bibliográficos
Autor(a) principal: Martins, M.R.
Data de Publicação: 2014
Outros Autores: Arantes, S., Candeias, M.F., Tinoco, M.T., Cruz-Morais, J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10174/12917
Resumo: Ethnopharmacological relevance: Schinus molle L. has been used in folk medicine as antibacterial, antiviral, topical antiseptic, antifungal, antioxidant, anti-inflammatory, anti-tumoural as well as antispasmodic and analgesic; however, there are few studies of pharmacological and toxicological properties of S. molle essential oils. Aim of the study: The aim of this study was to evaluate the antioxidant and antimicrobial activities of S. molle leaf and fruit essential oils, correlated with their chemical composition and evaluate their acute toxicity. Materials and methods: The chemical composition of S. molle leaf and fruit essential oils were evaluated by GC-FID and GC-MS. Antioxidant properties were determined using the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) free radical and β-carotene/linoleic acid methods. Antimicrobial properties were evaluated by the agar disc diffusion method and minimal inhibitory concentration assay. Toxicity in Artemia salina and acute toxicity with behavioural screening in mice were evaluated. Results: The dominant compounds found in leaf and fruit essential oils (EOs) were monoterpene hydrocarbons, namely -phellandrene, β-phellandrene, β-myrcene, limonene and α-pinene. EOs showed low scavenging antioxidant activity by the DPPH free radical method and a higher activity by the β-carotene/linoleic acid method. Antimicrobial activity of EOs was observed for Gram+, Gram– pathogenic bacteria and food spoilage fungi. EOs showed cytotoxicity for Artemia salina and lower toxicity in Swiss mice. Conclusions: The result showed that EOs of leaves and fruits of S. molle demonstrated antioxidant and antimicrobial properties, suggesting their potential use in food or pharmaceutical industries.
id RCAP_2ce2468d859ceb37c0483eb4477ffff3
oai_identifier_str oai:dspace.uevora.pt:10174/12917
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Antioxidant,antimicrobial and toxicological properties of Schinus molle L. essential oilsSchinus molleAmerican pepperessential oilsbiological activitiestoxicological studiesEthnopharmacological relevance: Schinus molle L. has been used in folk medicine as antibacterial, antiviral, topical antiseptic, antifungal, antioxidant, anti-inflammatory, anti-tumoural as well as antispasmodic and analgesic; however, there are few studies of pharmacological and toxicological properties of S. molle essential oils. Aim of the study: The aim of this study was to evaluate the antioxidant and antimicrobial activities of S. molle leaf and fruit essential oils, correlated with their chemical composition and evaluate their acute toxicity. Materials and methods: The chemical composition of S. molle leaf and fruit essential oils were evaluated by GC-FID and GC-MS. Antioxidant properties were determined using the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) free radical and β-carotene/linoleic acid methods. Antimicrobial properties were evaluated by the agar disc diffusion method and minimal inhibitory concentration assay. Toxicity in Artemia salina and acute toxicity with behavioural screening in mice were evaluated. Results: The dominant compounds found in leaf and fruit essential oils (EOs) were monoterpene hydrocarbons, namely -phellandrene, β-phellandrene, β-myrcene, limonene and α-pinene. EOs showed low scavenging antioxidant activity by the DPPH free radical method and a higher activity by the β-carotene/linoleic acid method. Antimicrobial activity of EOs was observed for Gram+, Gram– pathogenic bacteria and food spoilage fungi. EOs showed cytotoxicity for Artemia salina and lower toxicity in Swiss mice. Conclusions: The result showed that EOs of leaves and fruits of S. molle demonstrated antioxidant and antimicrobial properties, suggesting their potential use in food or pharmaceutical industries.Elsevier2015-02-25T10:00:53Z2015-02-252014-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10174/12917http://hdl.handle.net/10174/12917engMartins M.R., Arantes S., Candeias F., Tinoco M.T., Cruz Morais J. (2014) Antioxidant, antimicrobial and toxicological properties of Schinus molle L. essential oils. Journal of Ethnopharmacology 151: 485–492.485-492Journal of Ethnopharmacologymrm@uevora.ptsaa@uevora.ptmfbc@uevora.ptmtft@uevora.ptcruz_morais@live.com365Martins, M.R.Arantes, S.Candeias, M.F.Tinoco, M.T.Cruz-Morais, J.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-03T18:47:37Zoai:dspace.uevora.pt:10174/12917Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T01:01:56.153933Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Antioxidant,antimicrobial and toxicological properties of Schinus molle L. essential oils
title Antioxidant,antimicrobial and toxicological properties of Schinus molle L. essential oils
spellingShingle Antioxidant,antimicrobial and toxicological properties of Schinus molle L. essential oils
Martins, M.R.
Schinus molle
American pepper
essential oils
biological activities
toxicological studies
title_short Antioxidant,antimicrobial and toxicological properties of Schinus molle L. essential oils
title_full Antioxidant,antimicrobial and toxicological properties of Schinus molle L. essential oils
title_fullStr Antioxidant,antimicrobial and toxicological properties of Schinus molle L. essential oils
title_full_unstemmed Antioxidant,antimicrobial and toxicological properties of Schinus molle L. essential oils
title_sort Antioxidant,antimicrobial and toxicological properties of Schinus molle L. essential oils
author Martins, M.R.
author_facet Martins, M.R.
Arantes, S.
Candeias, M.F.
Tinoco, M.T.
Cruz-Morais, J.
author_role author
author2 Arantes, S.
Candeias, M.F.
Tinoco, M.T.
Cruz-Morais, J.
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Martins, M.R.
Arantes, S.
Candeias, M.F.
Tinoco, M.T.
Cruz-Morais, J.
dc.subject.por.fl_str_mv Schinus molle
American pepper
essential oils
biological activities
toxicological studies
topic Schinus molle
American pepper
essential oils
biological activities
toxicological studies
description Ethnopharmacological relevance: Schinus molle L. has been used in folk medicine as antibacterial, antiviral, topical antiseptic, antifungal, antioxidant, anti-inflammatory, anti-tumoural as well as antispasmodic and analgesic; however, there are few studies of pharmacological and toxicological properties of S. molle essential oils. Aim of the study: The aim of this study was to evaluate the antioxidant and antimicrobial activities of S. molle leaf and fruit essential oils, correlated with their chemical composition and evaluate their acute toxicity. Materials and methods: The chemical composition of S. molle leaf and fruit essential oils were evaluated by GC-FID and GC-MS. Antioxidant properties were determined using the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) free radical and β-carotene/linoleic acid methods. Antimicrobial properties were evaluated by the agar disc diffusion method and minimal inhibitory concentration assay. Toxicity in Artemia salina and acute toxicity with behavioural screening in mice were evaluated. Results: The dominant compounds found in leaf and fruit essential oils (EOs) were monoterpene hydrocarbons, namely -phellandrene, β-phellandrene, β-myrcene, limonene and α-pinene. EOs showed low scavenging antioxidant activity by the DPPH free radical method and a higher activity by the β-carotene/linoleic acid method. Antimicrobial activity of EOs was observed for Gram+, Gram– pathogenic bacteria and food spoilage fungi. EOs showed cytotoxicity for Artemia salina and lower toxicity in Swiss mice. Conclusions: The result showed that EOs of leaves and fruits of S. molle demonstrated antioxidant and antimicrobial properties, suggesting their potential use in food or pharmaceutical industries.
publishDate 2014
dc.date.none.fl_str_mv 2014-01-01T00:00:00Z
2015-02-25T10:00:53Z
2015-02-25
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10174/12917
http://hdl.handle.net/10174/12917
url http://hdl.handle.net/10174/12917
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Martins M.R., Arantes S., Candeias F., Tinoco M.T., Cruz Morais J. (2014) Antioxidant, antimicrobial and toxicological properties of Schinus molle L. essential oils. Journal of Ethnopharmacology 151: 485–492.
485-492
Journal of Ethnopharmacology
mrm@uevora.pt
saa@uevora.pt
mfbc@uevora.pt
mtft@uevora.pt
cruz_morais@live.com
365
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799136503163518976