Spacers and valved holding chambers : the risk of switching to different chambers
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2020 |
| Outros Autores: | , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10451/47547 |
Resumo: | © 2020 The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
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Spacers and valved holding chambers : the risk of switching to different chambersSpacerValved holding chamberInhalers© 2020 The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)Spacers are pressurized metered-dose inhaler (pMDI) accessory devices developed to reduce problems of poor inhaler technique with pMDIs. Spacers that feature a 1-way inspiratory valve are termed valved holding chambers (VHCs); they act as aerosol reservoirs, allowing the user to actuate the pMDI device and then inhale the medication in a 2-step process that helps users overcome challenges in coordinating pMDI actuation with inhalation. Both spacers and VHCs have been shown to increase fine particle delivery to the lungs, decrease oropharyngeal deposition, and reduce corticosteroid-related side effects such as throat irritation, dysphonia, and oral candidiasis commonly seen with the use of pMDIs alone. Spacers and VHCs are not all the same, and also are not interchangeable: the performance may vary according to their size, shape, material of manufacture and propensity to become electrostatically charged, their mode of interface with the patient, and the presence or otherwise of valves and feedback devices. Thus, pairing of a pMDI plus a spacer or a VHC should be considered as a unique delivery system. In this Rostrum we discuss the risk potential for a patient getting switched to a spacer or VHC that delivers a reduced dose medication.American Academy of Allergy, Asthma & ImmunologyRepositório da Universidade de LisboaLavorini, FedericoBarreto, Celestevan Boven, Job FMCarroll, WillConway, JoyCostello, Richard W.Dahl, Birthe HellqvistDekhuijzen, Richard PNHolmes, StephenLevy, MarkMolimard, MathieuRoche, NicholasRomán-Rodriguez, MiguelScichilone, NicolaScullion, JaneUsmani, Omar S.2021-04-26T11:06:14Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/47547engJ Allergy Clin Immunol Pract 2020;8:1569-732213-219810.1016/j.jaip.2019.12.0352213-2201info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:50:32Zoai:repositorio.ul.pt:10451/47547Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:59:33.804663Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Spacers and valved holding chambers : the risk of switching to different chambers |
| title |
Spacers and valved holding chambers : the risk of switching to different chambers |
| spellingShingle |
Spacers and valved holding chambers : the risk of switching to different chambers Lavorini, Federico Spacer Valved holding chamber Inhalers |
| title_short |
Spacers and valved holding chambers : the risk of switching to different chambers |
| title_full |
Spacers and valved holding chambers : the risk of switching to different chambers |
| title_fullStr |
Spacers and valved holding chambers : the risk of switching to different chambers |
| title_full_unstemmed |
Spacers and valved holding chambers : the risk of switching to different chambers |
| title_sort |
Spacers and valved holding chambers : the risk of switching to different chambers |
| author |
Lavorini, Federico |
| author_facet |
Lavorini, Federico Barreto, Celeste van Boven, Job FM Carroll, Will Conway, Joy Costello, Richard W. Dahl, Birthe Hellqvist Dekhuijzen, Richard PN Holmes, Stephen Levy, Mark Molimard, Mathieu Roche, Nicholas Román-Rodriguez, Miguel Scichilone, Nicola Scullion, Jane Usmani, Omar S. |
| author_role |
author |
| author2 |
Barreto, Celeste van Boven, Job FM Carroll, Will Conway, Joy Costello, Richard W. Dahl, Birthe Hellqvist Dekhuijzen, Richard PN Holmes, Stephen Levy, Mark Molimard, Mathieu Roche, Nicholas Román-Rodriguez, Miguel Scichilone, Nicola Scullion, Jane Usmani, Omar S. |
| author2_role |
author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
| dc.contributor.author.fl_str_mv |
Lavorini, Federico Barreto, Celeste van Boven, Job FM Carroll, Will Conway, Joy Costello, Richard W. Dahl, Birthe Hellqvist Dekhuijzen, Richard PN Holmes, Stephen Levy, Mark Molimard, Mathieu Roche, Nicholas Román-Rodriguez, Miguel Scichilone, Nicola Scullion, Jane Usmani, Omar S. |
| dc.subject.por.fl_str_mv |
Spacer Valved holding chamber Inhalers |
| topic |
Spacer Valved holding chamber Inhalers |
| description |
© 2020 The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
| publishDate |
2020 |
| dc.date.none.fl_str_mv |
2020 2020-01-01T00:00:00Z 2021-04-26T11:06:14Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10451/47547 |
| url |
http://hdl.handle.net/10451/47547 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
J Allergy Clin Immunol Pract 2020;8:1569-73 2213-2198 10.1016/j.jaip.2019.12.035 2213-2201 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
American Academy of Allergy, Asthma & Immunology |
| publisher.none.fl_str_mv |
American Academy of Allergy, Asthma & Immunology |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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