In silico characterization of molecular factors involved in metabolism and pathogenicity of Phytophthora cinnamomi
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/24436 |
Resumo: | Phytophthora cinnamomi is classified as one of the most devastating plant pathogens in the world. It has a destructive effect on more than 5000 horticultural and forestry species in the world, and especially on Castanea sativa. The genus Phytophthora belongs to the Class Oomycetes, a group of fungus like organisms which provoke plant diseases via motile zoospores. Control of this organism is considered very challenging because of the limited range of effective chemical inhibitors. The development of sustainable control measures for the future management of P. cinnamomi requires in-depth knowledge of the cellular and molecular bases of development and metabolism. The aim of this review was to identify molecular factors associated with the metabolism of P. cinnamomi by studying the genes implicated in fundamental metabolism using tools of bioinformatics. Also, some genes involved in pathogenicity will be cited and characterized, such as genes coding for transglycosylases. Genomic sequences of P. cinnamomi were analyzed using an open reading frame (ORF) finder. The identified ORFs products (proteins) were compared to sequences already described and with known functions present in databases such as NCBI and fungi database. In this way, homologous proteins were found, with the respective specific domains, to proteins involved in the metabolism and pathogenicity of Phytophthora ssp. |
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In silico characterization of molecular factors involved in metabolism and pathogenicity of Phytophthora cinnamomiCastanea sativaOomycetesOpen reading framePhytophthora cinnamomiZoosporesPhytophthora cinnamomi is classified as one of the most devastating plant pathogens in the world. It has a destructive effect on more than 5000 horticultural and forestry species in the world, and especially on Castanea sativa. The genus Phytophthora belongs to the Class Oomycetes, a group of fungus like organisms which provoke plant diseases via motile zoospores. Control of this organism is considered very challenging because of the limited range of effective chemical inhibitors. The development of sustainable control measures for the future management of P. cinnamomi requires in-depth knowledge of the cellular and molecular bases of development and metabolism. The aim of this review was to identify molecular factors associated with the metabolism of P. cinnamomi by studying the genes implicated in fundamental metabolism using tools of bioinformatics. Also, some genes involved in pathogenicity will be cited and characterized, such as genes coding for transglycosylases. Genomic sequences of P. cinnamomi were analyzed using an open reading frame (ORF) finder. The identified ORFs products (proteins) were compared to sequences already described and with known functions present in databases such as NCBI and fungi database. In this way, homologous proteins were found, with the respective specific domains, to proteins involved in the metabolism and pathogenicity of Phytophthora ssp.The authors are grateful to the Foundation for Science and Technology (FCT, Portugal) and FEDER under Programme PT2020 for financial support to CIMO (UID/AGR/00690/2019).Biblioteca Digital do IPBBoughanmi, Mohamed BelhassanBranco, IuliiaChoupina, Altino2018-01-19T10:00:00Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/24436engBoughanmi, Mohamed Belhassan; Branco, Iuliia; Choupina, Altino (2021) - In silico characterization of molecular factors involved in metabolism and pathogenicity of Phytophthora cinnamomi. Molecular Biology Reports. ISSN 0301-4851. p. 1-110301-485110.1007/s11033-021-06901-0info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:54:56Zoai:bibliotecadigital.ipb.pt:10198/24436Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:15:23.700350Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
In silico characterization of molecular factors involved in metabolism and pathogenicity of Phytophthora cinnamomi |
title |
In silico characterization of molecular factors involved in metabolism and pathogenicity of Phytophthora cinnamomi |
spellingShingle |
In silico characterization of molecular factors involved in metabolism and pathogenicity of Phytophthora cinnamomi Boughanmi, Mohamed Belhassan Castanea sativa Oomycetes Open reading frame Phytophthora cinnamomi Zoospores |
title_short |
In silico characterization of molecular factors involved in metabolism and pathogenicity of Phytophthora cinnamomi |
title_full |
In silico characterization of molecular factors involved in metabolism and pathogenicity of Phytophthora cinnamomi |
title_fullStr |
In silico characterization of molecular factors involved in metabolism and pathogenicity of Phytophthora cinnamomi |
title_full_unstemmed |
In silico characterization of molecular factors involved in metabolism and pathogenicity of Phytophthora cinnamomi |
title_sort |
In silico characterization of molecular factors involved in metabolism and pathogenicity of Phytophthora cinnamomi |
author |
Boughanmi, Mohamed Belhassan |
author_facet |
Boughanmi, Mohamed Belhassan Branco, Iuliia Choupina, Altino |
author_role |
author |
author2 |
Branco, Iuliia Choupina, Altino |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Boughanmi, Mohamed Belhassan Branco, Iuliia Choupina, Altino |
dc.subject.por.fl_str_mv |
Castanea sativa Oomycetes Open reading frame Phytophthora cinnamomi Zoospores |
topic |
Castanea sativa Oomycetes Open reading frame Phytophthora cinnamomi Zoospores |
description |
Phytophthora cinnamomi is classified as one of the most devastating plant pathogens in the world. It has a destructive effect on more than 5000 horticultural and forestry species in the world, and especially on Castanea sativa. The genus Phytophthora belongs to the Class Oomycetes, a group of fungus like organisms which provoke plant diseases via motile zoospores. Control of this organism is considered very challenging because of the limited range of effective chemical inhibitors. The development of sustainable control measures for the future management of P. cinnamomi requires in-depth knowledge of the cellular and molecular bases of development and metabolism. The aim of this review was to identify molecular factors associated with the metabolism of P. cinnamomi by studying the genes implicated in fundamental metabolism using tools of bioinformatics. Also, some genes involved in pathogenicity will be cited and characterized, such as genes coding for transglycosylases. Genomic sequences of P. cinnamomi were analyzed using an open reading frame (ORF) finder. The identified ORFs products (proteins) were compared to sequences already described and with known functions present in databases such as NCBI and fungi database. In this way, homologous proteins were found, with the respective specific domains, to proteins involved in the metabolism and pathogenicity of Phytophthora ssp. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-19T10:00:00Z 2021 2021-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/24436 |
url |
http://hdl.handle.net/10198/24436 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Boughanmi, Mohamed Belhassan; Branco, Iuliia; Choupina, Altino (2021) - In silico characterization of molecular factors involved in metabolism and pathogenicity of Phytophthora cinnamomi. Molecular Biology Reports. ISSN 0301-4851. p. 1-11 0301-4851 10.1007/s11033-021-06901-0 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799135436385288192 |