New Pickering emulsions stabilized with chitosan/collagen peptides nanoparticles: Synthesis, characterization and tracking of the nanoparticles after skin application
Autor(a) principal: | |
---|---|
Data de Publicação: | 2018 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/24345 |
Resumo: | Pickering emulsions based on biopolymeric particles are gaining increasing research recognition in numerous applications due to their biocompatibility and eco-friendliness. In this work, chitosan/collagen peptides nanoparticles were applied to stabilize Pickering emulsions for potential cosmetic applications. The nanoparticles had a contact angle of 78.02° ± 2.04°, reflecting their hydrophilic nature. Their average size and zeta potential were 32.27 nm and +59.7 mV, respectively. Confocal laser scanning microscopy (CLSM) showed that the nanoparticles become well-adsorbed at the oil-water interface. The emulsions displayed shear-thinning viscosity and gel-like texture. Their average droplet size ranged between 7.63 μm and 15.72 μm. CLSM skin tracking of the nanoparticles, after ex vivo skin application of the Pickering emulsions, revealed the ability of the emulsion droplets to penetrate the stratum corneum and deposit in deeper skin layers. The penetration degree depends on the concentration of the nanoparticles in the emulsion and on the contact time with the skin. These results provide new insights into the fate of the nanoparticles used to stabilize Pickering emulsions following their skin application. |
id |
RCAP_2f263c529c57d691206d1d01f8caf1da |
---|---|
oai_identifier_str |
oai:bibliotecadigital.ipb.pt:10198/24345 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
New Pickering emulsions stabilized with chitosan/collagen peptides nanoparticles: Synthesis, characterization and tracking of the nanoparticles after skin applicationChitosan/collagen peptidesEmulsion stabilityNanoparticles trackingPickering emulsionsRheologySkin applicationsPickering emulsions based on biopolymeric particles are gaining increasing research recognition in numerous applications due to their biocompatibility and eco-friendliness. In this work, chitosan/collagen peptides nanoparticles were applied to stabilize Pickering emulsions for potential cosmetic applications. The nanoparticles had a contact angle of 78.02° ± 2.04°, reflecting their hydrophilic nature. Their average size and zeta potential were 32.27 nm and +59.7 mV, respectively. Confocal laser scanning microscopy (CLSM) showed that the nanoparticles become well-adsorbed at the oil-water interface. The emulsions displayed shear-thinning viscosity and gel-like texture. Their average droplet size ranged between 7.63 μm and 15.72 μm. CLSM skin tracking of the nanoparticles, after ex vivo skin application of the Pickering emulsions, revealed the ability of the emulsion droplets to penetrate the stratum corneum and deposit in deeper skin layers. The penetration degree depends on the concentration of the nanoparticles in the emulsion and on the contact time with the skin. These results provide new insights into the fate of the nanoparticles used to stabilize Pickering emulsions following their skin application.This work was financially supported by the Base Funding—UIDB/50020/2020 of the Associate Laboratory LSRE-LCM—funded by national funds through FCT/MCTES (PIDDAC). The work was also supported by the Base Funding—(UIDB/00690/2020) of CIMO—Centro de Investigação de Montanha—funded by national funds through FCT/ MCTES (PIDDAC). The authors gratefully acknowledge the technical support provided by the Instituto de Investigaç˜ao e Inovação (i3s) at the University of Porto. Asma Sharkawy gratefully thanks the Foundation for Science and Technology (FCT, Portugal) for the doctoral grant (PD/BD/135085/2017), and Dr. Rui Faria from the LSRE-LCM (University of Porto) for the invaluable discussion.Biblioteca Digital do IPBSharkawy, AsmaBarreiro, M.F.Rodrigues, Alírio2018-01-19T10:00:00Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/24345engSharkawy, Asma; Barreiro, Maria Filomena; Rodrigues, Alírio E. (2021). New Pickering emulsions stabilized with chitosan/collagen peptides nanoparticles: Synthesis, characterization and tracking of the nanoparticles after skin application. Colloids and Surfaces A: Physicochemical and Engineering Aspects. ISSN 0927-7757. 616, p.0927775710.1016/j.colsurfa.2021.126327info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:54:28Zoai:bibliotecadigital.ipb.pt:10198/24345Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:15:11.767992Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
New Pickering emulsions stabilized with chitosan/collagen peptides nanoparticles: Synthesis, characterization and tracking of the nanoparticles after skin application |
title |
New Pickering emulsions stabilized with chitosan/collagen peptides nanoparticles: Synthesis, characterization and tracking of the nanoparticles after skin application |
spellingShingle |
New Pickering emulsions stabilized with chitosan/collagen peptides nanoparticles: Synthesis, characterization and tracking of the nanoparticles after skin application Sharkawy, Asma Chitosan/collagen peptides Emulsion stability Nanoparticles tracking Pickering emulsions Rheology Skin applications |
title_short |
New Pickering emulsions stabilized with chitosan/collagen peptides nanoparticles: Synthesis, characterization and tracking of the nanoparticles after skin application |
title_full |
New Pickering emulsions stabilized with chitosan/collagen peptides nanoparticles: Synthesis, characterization and tracking of the nanoparticles after skin application |
title_fullStr |
New Pickering emulsions stabilized with chitosan/collagen peptides nanoparticles: Synthesis, characterization and tracking of the nanoparticles after skin application |
title_full_unstemmed |
New Pickering emulsions stabilized with chitosan/collagen peptides nanoparticles: Synthesis, characterization and tracking of the nanoparticles after skin application |
title_sort |
New Pickering emulsions stabilized with chitosan/collagen peptides nanoparticles: Synthesis, characterization and tracking of the nanoparticles after skin application |
author |
Sharkawy, Asma |
author_facet |
Sharkawy, Asma Barreiro, M.F. Rodrigues, Alírio |
author_role |
author |
author2 |
Barreiro, M.F. Rodrigues, Alírio |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Sharkawy, Asma Barreiro, M.F. Rodrigues, Alírio |
dc.subject.por.fl_str_mv |
Chitosan/collagen peptides Emulsion stability Nanoparticles tracking Pickering emulsions Rheology Skin applications |
topic |
Chitosan/collagen peptides Emulsion stability Nanoparticles tracking Pickering emulsions Rheology Skin applications |
description |
Pickering emulsions based on biopolymeric particles are gaining increasing research recognition in numerous applications due to their biocompatibility and eco-friendliness. In this work, chitosan/collagen peptides nanoparticles were applied to stabilize Pickering emulsions for potential cosmetic applications. The nanoparticles had a contact angle of 78.02° ± 2.04°, reflecting their hydrophilic nature. Their average size and zeta potential were 32.27 nm and +59.7 mV, respectively. Confocal laser scanning microscopy (CLSM) showed that the nanoparticles become well-adsorbed at the oil-water interface. The emulsions displayed shear-thinning viscosity and gel-like texture. Their average droplet size ranged between 7.63 μm and 15.72 μm. CLSM skin tracking of the nanoparticles, after ex vivo skin application of the Pickering emulsions, revealed the ability of the emulsion droplets to penetrate the stratum corneum and deposit in deeper skin layers. The penetration degree depends on the concentration of the nanoparticles in the emulsion and on the contact time with the skin. These results provide new insights into the fate of the nanoparticles used to stabilize Pickering emulsions following their skin application. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-19T10:00:00Z 2021 2021-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/24345 |
url |
http://hdl.handle.net/10198/24345 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Sharkawy, Asma; Barreiro, Maria Filomena; Rodrigues, Alírio E. (2021). New Pickering emulsions stabilized with chitosan/collagen peptides nanoparticles: Synthesis, characterization and tracking of the nanoparticles after skin application. Colloids and Surfaces A: Physicochemical and Engineering Aspects. ISSN 0927-7757. 616, p. 09277757 10.1016/j.colsurfa.2021.126327 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799135433934766080 |