Influence of environmental factors in the in vitro dehydration of hydrogel and silicone hydrogel contact lenses
Autor(a) principal: | |
---|---|
Data de Publicação: | 2014 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://hdl.handle.net/1822/31247 |
Resumo: | Purpose: To analyze in vitro the influence of different environmental conditions on the dehydration pattern of seven currently marketed hydrogel (Hy) and silicone hydrogel (Si-Hy) contact lenses (CL). Methods: Three Hy and four Si-Hy CLs were evaluated. CLs were exposed to four different relative humidity (RH) conditions (5%, 30%, 50%, and 70%) and two air flow (AF) rates (0 and 2.75 m/seg) within an environmental chamber. Dehydration was assessed using the gravimetric method. Data were taken at baseline, 5, 10, 15, 20, 30, 45, 60, 90, and 120 minutes of exposure. Dehydration rate (DR), valid dehydration (VD) and stabilization time were calculated. Results: The interaction between RH, AF and the type of the CL material had a significant effect (p 0.03) on DR up to 60 minutes. The maximum differences in VD values among CL occurred around 15 minutes exposure varying from 25.16% to 42.75%. Stabilization time was quicker under the 5%RH with AF condition than under 70% RH without AF one for most CLs. Conclusions: Lower RH seems to increase CL dehydration being further accelerated with the AF presence. The dehydration pattern is material dependent, thus current marketed CLs behave differently under several controlled environmental conditions. Future in vivo studies should confirm these outcomes. |
id |
RCAP_303b05a6cd32abd25a3ff37fde51ef7b |
---|---|
oai_identifier_str |
oai:repositorium.sdum.uminho.pt:1822/31247 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Influence of environmental factors in the in vitro dehydration of hydrogel and silicone hydrogel contact lensesContact lensDehydrationRelative humidityAir flowEnvironmental chamberScience & TechnologyPurpose: To analyze in vitro the influence of different environmental conditions on the dehydration pattern of seven currently marketed hydrogel (Hy) and silicone hydrogel (Si-Hy) contact lenses (CL). Methods: Three Hy and four Si-Hy CLs were evaluated. CLs were exposed to four different relative humidity (RH) conditions (5%, 30%, 50%, and 70%) and two air flow (AF) rates (0 and 2.75 m/seg) within an environmental chamber. Dehydration was assessed using the gravimetric method. Data were taken at baseline, 5, 10, 15, 20, 30, 45, 60, 90, and 120 minutes of exposure. Dehydration rate (DR), valid dehydration (VD) and stabilization time were calculated. Results: The interaction between RH, AF and the type of the CL material had a significant effect (p 0.03) on DR up to 60 minutes. The maximum differences in VD values among CL occurred around 15 minutes exposure varying from 25.16% to 42.75%. Stabilization time was quicker under the 5%RH with AF condition than under 70% RH without AF one for most CLs. Conclusions: Lower RH seems to increase CL dehydration being further accelerated with the AF presence. The dehydration pattern is material dependent, thus current marketed CLs behave differently under several controlled environmental conditions. Future in vivo studies should confirm these outcomes.The present study was partially supported by Junta Castilla y Leon (GR217 and VA145A11-2); by Junta de Castilla y Leon and European Social Fund (VA317-11); by Junta de Castilla y Leon and European Regional Development Fund (O22/12/VA/0112) and by Ministerio de Economia y Competitividad through Centro para el Desarrollo Tecnologico Industrial (IDI-2006-0676).WileyUniversidade do MinhoMartín-Montañez, VicenteLópez-Miguel, AlbertoArroyo, CristinaMateo, María E.González-Méijome, José ManuelCalonge, MargaritaGonzález-García, María J.20142014-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/31247eng1552-498110.1002/jbm.b.3305724142398info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:41:51Zoai:repositorium.sdum.uminho.pt:1822/31247Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:38:56.270217Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Influence of environmental factors in the in vitro dehydration of hydrogel and silicone hydrogel contact lenses |
title |
Influence of environmental factors in the in vitro dehydration of hydrogel and silicone hydrogel contact lenses |
spellingShingle |
Influence of environmental factors in the in vitro dehydration of hydrogel and silicone hydrogel contact lenses Martín-Montañez, Vicente Contact lens Dehydration Relative humidity Air flow Environmental chamber Science & Technology |
title_short |
Influence of environmental factors in the in vitro dehydration of hydrogel and silicone hydrogel contact lenses |
title_full |
Influence of environmental factors in the in vitro dehydration of hydrogel and silicone hydrogel contact lenses |
title_fullStr |
Influence of environmental factors in the in vitro dehydration of hydrogel and silicone hydrogel contact lenses |
title_full_unstemmed |
Influence of environmental factors in the in vitro dehydration of hydrogel and silicone hydrogel contact lenses |
title_sort |
Influence of environmental factors in the in vitro dehydration of hydrogel and silicone hydrogel contact lenses |
author |
Martín-Montañez, Vicente |
author_facet |
Martín-Montañez, Vicente López-Miguel, Alberto Arroyo, Cristina Mateo, María E. González-Méijome, José Manuel Calonge, Margarita González-García, María J. |
author_role |
author |
author2 |
López-Miguel, Alberto Arroyo, Cristina Mateo, María E. González-Méijome, José Manuel Calonge, Margarita González-García, María J. |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Martín-Montañez, Vicente López-Miguel, Alberto Arroyo, Cristina Mateo, María E. González-Méijome, José Manuel Calonge, Margarita González-García, María J. |
dc.subject.por.fl_str_mv |
Contact lens Dehydration Relative humidity Air flow Environmental chamber Science & Technology |
topic |
Contact lens Dehydration Relative humidity Air flow Environmental chamber Science & Technology |
description |
Purpose: To analyze in vitro the influence of different environmental conditions on the dehydration pattern of seven currently marketed hydrogel (Hy) and silicone hydrogel (Si-Hy) contact lenses (CL). Methods: Three Hy and four Si-Hy CLs were evaluated. CLs were exposed to four different relative humidity (RH) conditions (5%, 30%, 50%, and 70%) and two air flow (AF) rates (0 and 2.75 m/seg) within an environmental chamber. Dehydration was assessed using the gravimetric method. Data were taken at baseline, 5, 10, 15, 20, 30, 45, 60, 90, and 120 minutes of exposure. Dehydration rate (DR), valid dehydration (VD) and stabilization time were calculated. Results: The interaction between RH, AF and the type of the CL material had a significant effect (p 0.03) on DR up to 60 minutes. The maximum differences in VD values among CL occurred around 15 minutes exposure varying from 25.16% to 42.75%. Stabilization time was quicker under the 5%RH with AF condition than under 70% RH without AF one for most CLs. Conclusions: Lower RH seems to increase CL dehydration being further accelerated with the AF presence. The dehydration pattern is material dependent, thus current marketed CLs behave differently under several controlled environmental conditions. Future in vivo studies should confirm these outcomes. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014 2014-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/1822/31247 |
url |
https://hdl.handle.net/1822/31247 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1552-4981 10.1002/jbm.b.33057 24142398 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Wiley |
publisher.none.fl_str_mv |
Wiley |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799132928743047168 |