Pneumonitis Associated with Fluoropolymer Waterproofing Agents: Case Report

Detalhes bibliográficos
Autor(a) principal: Almeida Borges, Joana
Data de Publicação: 2022
Outros Autores: Fradinho, Fátima, Ferreira, António Jorge
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17786
Resumo: Pneumonitis associated with fluoropolymer waterproofing agents, an entity with few reported cases, can result from occupational exposure. This condition has a rapid onset after exposure, usually resolves with supportive treatment but there could be chronic sequelae. The authors report the case of a 48-year-old male patient admitted to hospital with acute onset of dyspnea and chest pain after using an aerosolized fluoropolymer-containing waterproofing product. He presented tachypnea, leukocytosis, elevated C reactive protein, elevated serum lactate dehydrogenase and hypoxemic respiratory failure. Chest computed tomography revealed bilateral ground-glass opacities with peribronchovascular distribution. The patient was treated with oxygen and corticosteroid therapy, with clinical improvement. This chemical pneumonitis represents a diagnostic challenge since it implies a history of exposure to toxic agents and the pathophysiological mechanisms and safe exposure limits are still unknown.
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spelling Pneumonitis Associated with Fluoropolymer Waterproofing Agents: Case ReportPneumonite Associada a Impermeabilizantes com Fluoropolímeros: Caso ClínicoFluorocarbon Polymers/poisoningInhalation Exposure/adverse effectsOccupational Diseases/chemically inducedPneumonia/chemically inducedDoenças Ocupacionais/induzidas quimicamenteExposição por Inalação/efeitos adversosPneumonia/induzida quimicamentePolímeros de Fluorcarboneto/intoxicaçãoPneumonitis associated with fluoropolymer waterproofing agents, an entity with few reported cases, can result from occupational exposure. This condition has a rapid onset after exposure, usually resolves with supportive treatment but there could be chronic sequelae. The authors report the case of a 48-year-old male patient admitted to hospital with acute onset of dyspnea and chest pain after using an aerosolized fluoropolymer-containing waterproofing product. He presented tachypnea, leukocytosis, elevated C reactive protein, elevated serum lactate dehydrogenase and hypoxemic respiratory failure. Chest computed tomography revealed bilateral ground-glass opacities with peribronchovascular distribution. The patient was treated with oxygen and corticosteroid therapy, with clinical improvement. This chemical pneumonitis represents a diagnostic challenge since it implies a history of exposure to toxic agents and the pathophysiological mechanisms and safe exposure limits are still unknown.A pneumonite associada a impermeabilizantes com fluoropolímeros é uma entidade com poucos casos relatados e que pode resultar duma exposição ocupacional. Esta condição tem um início rápido após a exposição, que geralmente se resolve com tratamento de suporte, podendo resultar em sequelas crónicas. Os autores relatam o caso de um homem de 48 anos admitido no hospital com quadro agudo de dispneia e dor torácica após uso de impermeabilizante que continha fluoropolímeros em aerossol. Apresentava taquipneia, leucocitose, proteína C reativa elevada, níveis séricos de lactato desidrogenase elevados e insuficiência respiratória hipoxémica. A tomografia computadorizada do tórax revelou opacidades em vidro despolido bilaterais com distribuição peribroncovascular. O doente foi tratado com oxigenoterapia e corticoterapia com melhoria clínica. Esta pneumonite química representa um diagnóstico desafiante já que implica uma história de exposição a tóxicos, sendo que a fisiopatologia e os limites de segurança de exposição ainda são desconhecidos.Ordem dos Médicos2022-07-22info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17786Acta Médica Portuguesa; Vol. 36 No. 4 (2023): April; 275-277Acta Médica Portuguesa; Vol. 36 N.º 4 (2023): Abril; 275-2771646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17786https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17786/6700Direitos de Autor (c) 2022 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessAlmeida Borges, JoanaFradinho, FátimaFerreira, António Jorge2023-04-09T03:00:45Zoai:ojs.www.actamedicaportuguesa.com:article/17786Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:21:00.243323Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Pneumonitis Associated with Fluoropolymer Waterproofing Agents: Case Report
Pneumonite Associada a Impermeabilizantes com Fluoropolímeros: Caso Clínico
title Pneumonitis Associated with Fluoropolymer Waterproofing Agents: Case Report
spellingShingle Pneumonitis Associated with Fluoropolymer Waterproofing Agents: Case Report
Almeida Borges, Joana
Fluorocarbon Polymers/poisoning
Inhalation Exposure/adverse effects
Occupational Diseases/chemically induced
Pneumonia/chemically induced
Doenças Ocupacionais/induzidas quimicamente
Exposição por Inalação/efeitos adversos
Pneumonia/induzida quimicamente
Polímeros de Fluorcarboneto/intoxicação
title_short Pneumonitis Associated with Fluoropolymer Waterproofing Agents: Case Report
title_full Pneumonitis Associated with Fluoropolymer Waterproofing Agents: Case Report
title_fullStr Pneumonitis Associated with Fluoropolymer Waterproofing Agents: Case Report
title_full_unstemmed Pneumonitis Associated with Fluoropolymer Waterproofing Agents: Case Report
title_sort Pneumonitis Associated with Fluoropolymer Waterproofing Agents: Case Report
author Almeida Borges, Joana
author_facet Almeida Borges, Joana
Fradinho, Fátima
Ferreira, António Jorge
author_role author
author2 Fradinho, Fátima
Ferreira, António Jorge
author2_role author
author
dc.contributor.author.fl_str_mv Almeida Borges, Joana
Fradinho, Fátima
Ferreira, António Jorge
dc.subject.por.fl_str_mv Fluorocarbon Polymers/poisoning
Inhalation Exposure/adverse effects
Occupational Diseases/chemically induced
Pneumonia/chemically induced
Doenças Ocupacionais/induzidas quimicamente
Exposição por Inalação/efeitos adversos
Pneumonia/induzida quimicamente
Polímeros de Fluorcarboneto/intoxicação
topic Fluorocarbon Polymers/poisoning
Inhalation Exposure/adverse effects
Occupational Diseases/chemically induced
Pneumonia/chemically induced
Doenças Ocupacionais/induzidas quimicamente
Exposição por Inalação/efeitos adversos
Pneumonia/induzida quimicamente
Polímeros de Fluorcarboneto/intoxicação
description Pneumonitis associated with fluoropolymer waterproofing agents, an entity with few reported cases, can result from occupational exposure. This condition has a rapid onset after exposure, usually resolves with supportive treatment but there could be chronic sequelae. The authors report the case of a 48-year-old male patient admitted to hospital with acute onset of dyspnea and chest pain after using an aerosolized fluoropolymer-containing waterproofing product. He presented tachypnea, leukocytosis, elevated C reactive protein, elevated serum lactate dehydrogenase and hypoxemic respiratory failure. Chest computed tomography revealed bilateral ground-glass opacities with peribronchovascular distribution. The patient was treated with oxygen and corticosteroid therapy, with clinical improvement. This chemical pneumonitis represents a diagnostic challenge since it implies a history of exposure to toxic agents and the pathophysiological mechanisms and safe exposure limits are still unknown.
publishDate 2022
dc.date.none.fl_str_mv 2022-07-22
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17786
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17786
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17786
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17786/6700
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2022 Acta Médica Portuguesa
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos de Autor (c) 2022 Acta Médica Portuguesa
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 36 No. 4 (2023): April; 275-277
Acta Médica Portuguesa; Vol. 36 N.º 4 (2023): Abril; 275-277
1646-0758
0870-399X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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