Adjuvant antithrombotic therapy in ST-elevation myocardial infarction : contemporaneous portuguese cross-sectional data
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2019 |
| Outros Autores: | , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10451/43858 |
Resumo: | © 2020 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U. This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
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Adjuvant antithrombotic therapy in ST-elevation myocardial infarction : contemporaneous portuguese cross-sectional dataTerapêutica antitrombótica adjuvante no enfarte do miocárdio com elevação do segment ST : dados portugueses transversais contemporâneosMyocardial infarctionAntiplateletAnticoagulantAntithromboticAdjuvant© 2020 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U. This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).Introduction: The standard of care for acute ST-elevation myocardial infarction (STEMI) includes the activation of a STEMI care network, the administration of adjuvant medical therapy, and reperfusion through primary percutaneous coronary intervention (PCI). While primary PCI is nowadays the first option for the treatment of patients with STEMI, antithrombotic therapy, including antiplatelet and anticoagulant agents, is the cornerstone of pharmacological treatment to optimize their clinical outcomes. Objective: The aim of this study was to describe contemporaneous real-world patterns of use of antithrombotic treatments in Portugal for STEMI patients undergoing primary PCI. Methods: An observational, retrospective cross-sectional study was performed for the year 2016, based on data from two national registries: the Portuguese Registry on Acute Coronary Syndromes (ProACS) and the Portuguese Registry on Interventional Cardiology (PRIC). Data on oral antiplatelet and procedural intravenous antithrombotic drugs were retrieved. Results: In 2016, the ProACS enrolled 534 STEMI patients treated with primary PCI, while the PRIC registry reported data on 2625 STEMI patients. Of these, 99.6% were treated with aspirin and 75.6% with dual antiplatelet therapy (mostly clopidogrel). GP IIb/IIIa inhibitors (mostly abciximab) were used in 11.6% of cases. Heparins were used in 80% of cases (78% unfractionated heparin [UFH] and 2% low molecular weight heparin). None of the patients included in the registry were treated with cangrelor, prasugrel or bivalirudin. Missing data are one of the main limitations of the registries. Conclusions: In 2016, according to data from these national registries, almost all patients with STEMI were treated with aspirin and 76% with dual antiplatelet agents, mostly clopidogrel. GP IIb/IIIa inhibitors were used in few patients, and UFH was the most prevalent parenteral anticoagulant drug.ElsevierRepositório da Universidade de LisboaCaldeira, DanielPereira, HélderMarques, AnaAlegria, SofiaCalisto, JoãoCanas da Silva, PedroRibeiro, Vasco GamaSilva, João CarlosSeixo, FilipeAbreu, Pedro Farto eTeles, Rui CampanteFernandes, RenatoCarvalho, Henrique Cyrne2020-06-18T10:50:10Z20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/43858engRev Port Cardiol. 2019; 38 (11): 809-8140870-255110.1016/j.repc.2019.02.0152174-2030info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:44:32Zoai:repositorio.ul.pt:10451/43858Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:56:35.715153Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Adjuvant antithrombotic therapy in ST-elevation myocardial infarction : contemporaneous portuguese cross-sectional data Terapêutica antitrombótica adjuvante no enfarte do miocárdio com elevação do segment ST : dados portugueses transversais contemporâneos |
| title |
Adjuvant antithrombotic therapy in ST-elevation myocardial infarction : contemporaneous portuguese cross-sectional data |
| spellingShingle |
Adjuvant antithrombotic therapy in ST-elevation myocardial infarction : contemporaneous portuguese cross-sectional data Caldeira, Daniel Myocardial infarction Antiplatelet Anticoagulant Antithrombotic Adjuvant |
| title_short |
Adjuvant antithrombotic therapy in ST-elevation myocardial infarction : contemporaneous portuguese cross-sectional data |
| title_full |
Adjuvant antithrombotic therapy in ST-elevation myocardial infarction : contemporaneous portuguese cross-sectional data |
| title_fullStr |
Adjuvant antithrombotic therapy in ST-elevation myocardial infarction : contemporaneous portuguese cross-sectional data |
| title_full_unstemmed |
Adjuvant antithrombotic therapy in ST-elevation myocardial infarction : contemporaneous portuguese cross-sectional data |
| title_sort |
Adjuvant antithrombotic therapy in ST-elevation myocardial infarction : contemporaneous portuguese cross-sectional data |
| author |
Caldeira, Daniel |
| author_facet |
Caldeira, Daniel Pereira, Hélder Marques, Ana Alegria, Sofia Calisto, João Canas da Silva, Pedro Ribeiro, Vasco Gama Silva, João Carlos Seixo, Filipe Abreu, Pedro Farto e Teles, Rui Campante Fernandes, Renato Carvalho, Henrique Cyrne |
| author_role |
author |
| author2 |
Pereira, Hélder Marques, Ana Alegria, Sofia Calisto, João Canas da Silva, Pedro Ribeiro, Vasco Gama Silva, João Carlos Seixo, Filipe Abreu, Pedro Farto e Teles, Rui Campante Fernandes, Renato Carvalho, Henrique Cyrne |
| author2_role |
author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
| dc.contributor.author.fl_str_mv |
Caldeira, Daniel Pereira, Hélder Marques, Ana Alegria, Sofia Calisto, João Canas da Silva, Pedro Ribeiro, Vasco Gama Silva, João Carlos Seixo, Filipe Abreu, Pedro Farto e Teles, Rui Campante Fernandes, Renato Carvalho, Henrique Cyrne |
| dc.subject.por.fl_str_mv |
Myocardial infarction Antiplatelet Anticoagulant Antithrombotic Adjuvant |
| topic |
Myocardial infarction Antiplatelet Anticoagulant Antithrombotic Adjuvant |
| description |
© 2020 Sociedade Portuguesa de Cardiologia. Published by Elsevier España, S.L.U. This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| publishDate |
2019 |
| dc.date.none.fl_str_mv |
2019 2019-01-01T00:00:00Z 2020-06-18T10:50:10Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/10451/43858 |
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http://hdl.handle.net/10451/43858 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Rev Port Cardiol. 2019; 38 (11): 809-814 0870-2551 10.1016/j.repc.2019.02.015 2174-2030 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Elsevier |
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Elsevier |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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