The Influence of Obesity in the Autonomic Nervous System Activity in School-Aged Children in Northern Portugal: A Cross-Sectional Study
Autor(a) principal: | |
---|---|
Data de Publicação: | 2023 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17144 |
Resumo: | Introduction: Obesity is one of the most prevalent chronic diseases in childhood, being an important public health issue. Excessive weight has been associated with autonomic dysfunction but the evidence in children is scarce. Therefore, the aim of this study was to assess the effect of overweight and obesity on the autonomic nervous system activity, in children.Material and Methods: Data from a cross-sectional study of 1602 children, aged 7 to 12 years, was used and 858 children were included in the analysis. Body mass index was calculated and classified according to criteria of the World Health Organization (WHO), Centers for Disease Control and Prevention (CDC) and the International Obesity Task Force (IOTF). Body composition was characterized by bioelectrical impedance. Linear regression models were used to determine the association between body mass index, body composition and the autonomic nervous system activity, assessed by pupillometry.Results: Average dilation velocity was higher among children with obesity, according to the CDC and percentage of body fat criteria (β = 0.053, 95% CI = 0.005 to 0.101 and β = 0.063, 95% CI = 0.016 to 0.109, respectively). The same trend was observed for WHO and IOTF criteria (β = 0.045, 95% CI = -0.001 to 0.091, and β = 0.055, 95% CI = -0.001 to 0.111, respectively). CDC and WHO body mass index z-scores were also positively associated with the values of average dilation velocity (rs = 0.030, p = 0.048; and rs = 0.027, p = 0.042, respectively).Conclusion: Our findings suggest an association between body mass and changes in the autonomic activity, Moreover, this study provides proof of concept for interventions targeting the prevention/treatment of obesity in children that may offer some benefit in re-establishing the balance of the autonomic nervous system, and subsequently preventing the consequences associated with the autonomic nervous system dysfunction. |
id |
RCAP_31455a0f3b3eaec3cd9a7e7fc9c44d74 |
---|---|
oai_identifier_str |
oai:ojs.www.actamedicaportuguesa.com:article/17144 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
The Influence of Obesity in the Autonomic Nervous System Activity in School-Aged Children in Northern Portugal: A Cross-Sectional StudyA Influência da Obesidade na Atividade do Sistema Nervoso Central em Crianças em Idade Escolar no Norte de Portugal: Um Estudo TransversalAutonomic Nervous System/physiopathologyChildObesity/physiopathologyPediatric ObesityPortugalCriançaObesidade/fisiopatologiaObesidade PediátricaPortugalSistema Nervoso Autónomo/fisiopatologiaIntroduction: Obesity is one of the most prevalent chronic diseases in childhood, being an important public health issue. Excessive weight has been associated with autonomic dysfunction but the evidence in children is scarce. Therefore, the aim of this study was to assess the effect of overweight and obesity on the autonomic nervous system activity, in children.Material and Methods: Data from a cross-sectional study of 1602 children, aged 7 to 12 years, was used and 858 children were included in the analysis. Body mass index was calculated and classified according to criteria of the World Health Organization (WHO), Centers for Disease Control and Prevention (CDC) and the International Obesity Task Force (IOTF). Body composition was characterized by bioelectrical impedance. Linear regression models were used to determine the association between body mass index, body composition and the autonomic nervous system activity, assessed by pupillometry.Results: Average dilation velocity was higher among children with obesity, according to the CDC and percentage of body fat criteria (β = 0.053, 95% CI = 0.005 to 0.101 and β = 0.063, 95% CI = 0.016 to 0.109, respectively). The same trend was observed for WHO and IOTF criteria (β = 0.045, 95% CI = -0.001 to 0.091, and β = 0.055, 95% CI = -0.001 to 0.111, respectively). CDC and WHO body mass index z-scores were also positively associated with the values of average dilation velocity (rs = 0.030, p = 0.048; and rs = 0.027, p = 0.042, respectively).Conclusion: Our findings suggest an association between body mass and changes in the autonomic activity, Moreover, this study provides proof of concept for interventions targeting the prevention/treatment of obesity in children that may offer some benefit in re-establishing the balance of the autonomic nervous system, and subsequently preventing the consequences associated with the autonomic nervous system dysfunction.Introdução: A obesidade é uma das doenças crónicas mais prevalentes na infância. O peso excessivo tem sido associado à disfunção autonómica, mas as evidências em crianças são escassas. Este estudo teve como objetivo avaliar o efeito da pré-obesidade e obesidade na atividade do sistema nervoso autónomo, em crianças.Material e Métodos: Foram utilizados dados de um estudo transversal com 1602 crianças, sendo que 858 foram incluídas na análise. O índice de massa corporal foi calculado e classificado de acordo com a Organização Mundial da Saúde (OMS), Centro de Controlo e Prevenção de Doenças dos Estados Unidos (CDC) e a Task Force Internacional para a Obesidade (IOTF). A composição corporal foi caracterizada por impedância bioelétrica. Modelos de regressão linear foram usados para determinar a associação entre o índice de massa corporal, a composição corporal e a atividade do sistema nervoso autónomo, avaliada por pupilometria.Resultados: A velocidade média de dilatação foi maior entre crianças com obesidade, segundo os critérios do CDC e percentagem de gordura corporal (β = 0,053, IC 95% = 0,005 a 0,101 e β = 0,063, IC 95% = 0,016 a 0,109, respetivamente). Igual tendência foi observada para os critérios da OMS e IOTF (β = 0,045, IC 95% = -0,001 a 0,091 e β = 0,055, IC 95% = -0,001 a 0,111, respetivamente). Os z-scores de índice de massa corporal do CDC e OMS também se associaram positivamente aos valores da velocidade média de dilatação (rs = 0,030, p = 0,048; e rs = 0,027, p = 0,042, respetivamente).Conclusão: Os resultados sugerem uma associação entre a massa corporal e alterações na atividade do sistema nervoso autónomo Este estudo fornece prova de conceito para intervenções direcionadas à prevenção/tratamento da obesidade em crianças, podendo favorecer o restabelecimento do equilíbrio do sistema nervoso autónomo e, assim, prevenir as consequências associadas à sua disfunção.Ordem dos Médicos2023-05-02info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17144Acta Médica Portuguesa; Vol. 36 No. 5 (2023): May; 317-325Acta Médica Portuguesa; Vol. 36 N.º 5 (2023): Maio; 317-3251646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17144https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17144/15125https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17144/15117Direitos de Autor (c) 2023 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessGonçalves Teixeira, BeatrizPaciência, InêsCavaleiro Rufo, JoãoMendes, FranciscaFarraia, MarianaPadrão, PatríciaMoreira, PedroMoreira, André2023-05-07T03:00:38Zoai:ojs.www.actamedicaportuguesa.com:article/17144Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:50:59.303661Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
The Influence of Obesity in the Autonomic Nervous System Activity in School-Aged Children in Northern Portugal: A Cross-Sectional Study A Influência da Obesidade na Atividade do Sistema Nervoso Central em Crianças em Idade Escolar no Norte de Portugal: Um Estudo Transversal |
title |
The Influence of Obesity in the Autonomic Nervous System Activity in School-Aged Children in Northern Portugal: A Cross-Sectional Study |
spellingShingle |
The Influence of Obesity in the Autonomic Nervous System Activity in School-Aged Children in Northern Portugal: A Cross-Sectional Study Gonçalves Teixeira, Beatriz Autonomic Nervous System/physiopathology Child Obesity/physiopathology Pediatric Obesity Portugal Criança Obesidade/fisiopatologia Obesidade Pediátrica Portugal Sistema Nervoso Autónomo/fisiopatologia |
title_short |
The Influence of Obesity in the Autonomic Nervous System Activity in School-Aged Children in Northern Portugal: A Cross-Sectional Study |
title_full |
The Influence of Obesity in the Autonomic Nervous System Activity in School-Aged Children in Northern Portugal: A Cross-Sectional Study |
title_fullStr |
The Influence of Obesity in the Autonomic Nervous System Activity in School-Aged Children in Northern Portugal: A Cross-Sectional Study |
title_full_unstemmed |
The Influence of Obesity in the Autonomic Nervous System Activity in School-Aged Children in Northern Portugal: A Cross-Sectional Study |
title_sort |
The Influence of Obesity in the Autonomic Nervous System Activity in School-Aged Children in Northern Portugal: A Cross-Sectional Study |
author |
Gonçalves Teixeira, Beatriz |
author_facet |
Gonçalves Teixeira, Beatriz Paciência, Inês Cavaleiro Rufo, João Mendes, Francisca Farraia, Mariana Padrão, Patrícia Moreira, Pedro Moreira, André |
author_role |
author |
author2 |
Paciência, Inês Cavaleiro Rufo, João Mendes, Francisca Farraia, Mariana Padrão, Patrícia Moreira, Pedro Moreira, André |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Gonçalves Teixeira, Beatriz Paciência, Inês Cavaleiro Rufo, João Mendes, Francisca Farraia, Mariana Padrão, Patrícia Moreira, Pedro Moreira, André |
dc.subject.por.fl_str_mv |
Autonomic Nervous System/physiopathology Child Obesity/physiopathology Pediatric Obesity Portugal Criança Obesidade/fisiopatologia Obesidade Pediátrica Portugal Sistema Nervoso Autónomo/fisiopatologia |
topic |
Autonomic Nervous System/physiopathology Child Obesity/physiopathology Pediatric Obesity Portugal Criança Obesidade/fisiopatologia Obesidade Pediátrica Portugal Sistema Nervoso Autónomo/fisiopatologia |
description |
Introduction: Obesity is one of the most prevalent chronic diseases in childhood, being an important public health issue. Excessive weight has been associated with autonomic dysfunction but the evidence in children is scarce. Therefore, the aim of this study was to assess the effect of overweight and obesity on the autonomic nervous system activity, in children.Material and Methods: Data from a cross-sectional study of 1602 children, aged 7 to 12 years, was used and 858 children were included in the analysis. Body mass index was calculated and classified according to criteria of the World Health Organization (WHO), Centers for Disease Control and Prevention (CDC) and the International Obesity Task Force (IOTF). Body composition was characterized by bioelectrical impedance. Linear regression models were used to determine the association between body mass index, body composition and the autonomic nervous system activity, assessed by pupillometry.Results: Average dilation velocity was higher among children with obesity, according to the CDC and percentage of body fat criteria (β = 0.053, 95% CI = 0.005 to 0.101 and β = 0.063, 95% CI = 0.016 to 0.109, respectively). The same trend was observed for WHO and IOTF criteria (β = 0.045, 95% CI = -0.001 to 0.091, and β = 0.055, 95% CI = -0.001 to 0.111, respectively). CDC and WHO body mass index z-scores were also positively associated with the values of average dilation velocity (rs = 0.030, p = 0.048; and rs = 0.027, p = 0.042, respectively).Conclusion: Our findings suggest an association between body mass and changes in the autonomic activity, Moreover, this study provides proof of concept for interventions targeting the prevention/treatment of obesity in children that may offer some benefit in re-establishing the balance of the autonomic nervous system, and subsequently preventing the consequences associated with the autonomic nervous system dysfunction. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-05-02 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17144 |
url |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17144 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17144 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17144/15125 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17144/15117 |
dc.rights.driver.fl_str_mv |
Direitos de Autor (c) 2023 Acta Médica Portuguesa info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Direitos de Autor (c) 2023 Acta Médica Portuguesa |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 36 No. 5 (2023): May; 317-325 Acta Médica Portuguesa; Vol. 36 N.º 5 (2023): Maio; 317-325 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799131588566450176 |