MtDNA profile of West Africa Guineans: towards a better understanding of the Senegambia region
Autor(a) principal: | |
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Data de Publicação: | 2004 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.13/3044 |
Resumo: | The matrilineal genetic composition of 372 samples from the Republic of Guiné-Bissau (West African coast) was studied using RFLPs and partial sequencing of the mtDNA control and coding region. The majority of the mtDNA lineages of Guineans (94%) belong to West African specific sub-clusters of L0-L3 haplogroups. A new L3 sub-cluster (L3h) that is found in both eastern and western Africa is present at moderately low frequencies in Guinean populations. A non-random distribution of haplogroups U5 in the Fula group, the U6 among the "Brame" linguistic family and M1 in the Balanta-Djola group, suggests a correlation between the genetic and linguistic affiliation of Guinean populations. The presence of M1 in Balanta populations supports the earlier suggestion of their Sudanese origin. Haplogroups U5 and U6, on the other hand, were found to be restricted to populations that are thought to represent the descendants of a southern expansion of Berbers. Particular haplotypes, found almost exclusively in East-African populations, were found in some ethnic groups with an oral tradition claiming Sudanese origin. |
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MtDNA profile of West Africa Guineans: towards a better understanding of the Senegambia regionAfrican Continental Ancestry GroupDNA, MitochondrialEvolution, MolecularGenetic MarkersGenetic VariationGeographyGuinea-BissauHaplotypesHumansPhylogenyPolymorphism, Restriction Fragment LengthSequence Analysis, DNAGenetics, Population.Faculdade de Ciências da VidaThe matrilineal genetic composition of 372 samples from the Republic of Guiné-Bissau (West African coast) was studied using RFLPs and partial sequencing of the mtDNA control and coding region. The majority of the mtDNA lineages of Guineans (94%) belong to West African specific sub-clusters of L0-L3 haplogroups. A new L3 sub-cluster (L3h) that is found in both eastern and western Africa is present at moderately low frequencies in Guinean populations. A non-random distribution of haplogroups U5 in the Fula group, the U6 among the "Brame" linguistic family and M1 in the Balanta-Djola group, suggests a correlation between the genetic and linguistic affiliation of Guinean populations. The presence of M1 in Balanta populations supports the earlier suggestion of their Sudanese origin. Haplogroups U5 and U6, on the other hand, were found to be restricted to populations that are thought to represent the descendants of a southern expansion of Berbers. Particular haplotypes, found almost exclusively in East-African populations, were found in some ethnic groups with an oral tradition claiming Sudanese origin.WileyDigitUMaRosa, AlexandraBrehm, AntónioKivisild, ToomasMetspalu, EneVillems, Richard2020-12-28T14:24:06Z2004-07-01T00:00:00Z2004-07-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.13/3044engRosa, A., Brehm, A., Kivisild, T., Metspalu, E., & Villems, R. (2004). MtDNA profile of West Africa Guineans: towards a better understanding of the Senegambia region. Annals of Human Genetics, 68(4), 340-352.10.1046/j.1529-8817.2004.00100.xinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-05T12:55:56Zoai:digituma.uma.pt:10400.13/3044Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:05:53.486013Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
MtDNA profile of West Africa Guineans: towards a better understanding of the Senegambia region |
title |
MtDNA profile of West Africa Guineans: towards a better understanding of the Senegambia region |
spellingShingle |
MtDNA profile of West Africa Guineans: towards a better understanding of the Senegambia region Rosa, Alexandra African Continental Ancestry Group DNA, Mitochondrial Evolution, Molecular Genetic Markers Genetic Variation Geography Guinea-Bissau Haplotypes Humans Phylogeny Polymorphism, Restriction Fragment Length Sequence Analysis, DNA Genetics, Population . Faculdade de Ciências da Vida |
title_short |
MtDNA profile of West Africa Guineans: towards a better understanding of the Senegambia region |
title_full |
MtDNA profile of West Africa Guineans: towards a better understanding of the Senegambia region |
title_fullStr |
MtDNA profile of West Africa Guineans: towards a better understanding of the Senegambia region |
title_full_unstemmed |
MtDNA profile of West Africa Guineans: towards a better understanding of the Senegambia region |
title_sort |
MtDNA profile of West Africa Guineans: towards a better understanding of the Senegambia region |
author |
Rosa, Alexandra |
author_facet |
Rosa, Alexandra Brehm, António Kivisild, Toomas Metspalu, Ene Villems, Richard |
author_role |
author |
author2 |
Brehm, António Kivisild, Toomas Metspalu, Ene Villems, Richard |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
DigitUMa |
dc.contributor.author.fl_str_mv |
Rosa, Alexandra Brehm, António Kivisild, Toomas Metspalu, Ene Villems, Richard |
dc.subject.por.fl_str_mv |
African Continental Ancestry Group DNA, Mitochondrial Evolution, Molecular Genetic Markers Genetic Variation Geography Guinea-Bissau Haplotypes Humans Phylogeny Polymorphism, Restriction Fragment Length Sequence Analysis, DNA Genetics, Population . Faculdade de Ciências da Vida |
topic |
African Continental Ancestry Group DNA, Mitochondrial Evolution, Molecular Genetic Markers Genetic Variation Geography Guinea-Bissau Haplotypes Humans Phylogeny Polymorphism, Restriction Fragment Length Sequence Analysis, DNA Genetics, Population . Faculdade de Ciências da Vida |
description |
The matrilineal genetic composition of 372 samples from the Republic of Guiné-Bissau (West African coast) was studied using RFLPs and partial sequencing of the mtDNA control and coding region. The majority of the mtDNA lineages of Guineans (94%) belong to West African specific sub-clusters of L0-L3 haplogroups. A new L3 sub-cluster (L3h) that is found in both eastern and western Africa is present at moderately low frequencies in Guinean populations. A non-random distribution of haplogroups U5 in the Fula group, the U6 among the "Brame" linguistic family and M1 in the Balanta-Djola group, suggests a correlation between the genetic and linguistic affiliation of Guinean populations. The presence of M1 in Balanta populations supports the earlier suggestion of their Sudanese origin. Haplogroups U5 and U6, on the other hand, were found to be restricted to populations that are thought to represent the descendants of a southern expansion of Berbers. Particular haplotypes, found almost exclusively in East-African populations, were found in some ethnic groups with an oral tradition claiming Sudanese origin. |
publishDate |
2004 |
dc.date.none.fl_str_mv |
2004-07-01T00:00:00Z 2004-07-01T00:00:00Z 2020-12-28T14:24:06Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.13/3044 |
url |
http://hdl.handle.net/10400.13/3044 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Rosa, A., Brehm, A., Kivisild, T., Metspalu, E., & Villems, R. (2004). MtDNA profile of West Africa Guineans: towards a better understanding of the Senegambia region. Annals of Human Genetics, 68(4), 340-352. 10.1046/j.1529-8817.2004.00100.x |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Wiley |
publisher.none.fl_str_mv |
Wiley |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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