Age-related expression of TGF beta family receptors in human cumulus oophorus cells

Detalhes bibliográficos
Autor(a) principal: Ribeiro, A.
Data de Publicação: 2017
Outros Autores: Freitas, C., Matos, L., Gouveia, A., Gomes, F., Silva Carvalho, J. L., Almeida, H.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/33005
Resumo: During ovarian follicle growth, local cellular interactions are essential for oocyte quality acquisition and successful fertilization. While cumulus cells (CCs) nurture oocytes, they also deliver oocyte-secreted factors (OSFs) that activate receptors on CCs. We hypothesized that disturbance of those interactions contributes to age-related lower reproductive success in women submitted to assisted reproductive technology treatments.
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spelling Age-related expression of TGF beta family receptors in human cumulus oophorus cellsAdultAnaplastic Lymphoma KinaseBone Morphogenetic Protein Receptors, Type IBone Morphogenetic Protein Receptors, Type IICumulus CellsFemaleFertilization in VitroGene Expression Regulation, DevelopmentalHumansMiddle AgedOocytesOvarian FollicleProtein-Serine-Threonine KinasesReceptor Protein-Tyrosine KinasesReceptor, Transforming Growth Factor-beta Type IReceptors, Transforming Growth Factor betaReproductive Techniques, AssistedPortugalDuring ovarian follicle growth, local cellular interactions are essential for oocyte quality acquisition and successful fertilization. While cumulus cells (CCs) nurture oocytes, they also deliver oocyte-secreted factors (OSFs) that activate receptors on CCs. We hypothesized that disturbance of those interactions contributes to age-related lower reproductive success in women submitted to assisted reproductive technology treatments.SpringerRepositório ComumRibeiro, A.Freitas, C.Matos, L.Gouveia, A.Gomes, F.Silva Carvalho, J. L.Almeida, H.2020-07-28T10:15:02Z20172017-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/33005engRibeiro, A., Freitas, C., Matos, L. et al. Age-related expression f TGF beta family receptors in human cumulus oophorus cells. J Assist Reprod Genet 34, 1121–1129 (2017).1058-0468 (Print) 1573-7330 (Online)10.1007/s10815-017-0930-6info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-10T02:16:49Zoai:comum.rcaap.pt:10400.26/33005Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:34:27.229975Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Age-related expression of TGF beta family receptors in human cumulus oophorus cells
title Age-related expression of TGF beta family receptors in human cumulus oophorus cells
spellingShingle Age-related expression of TGF beta family receptors in human cumulus oophorus cells
Ribeiro, A.
Adult
Anaplastic Lymphoma Kinase
Bone Morphogenetic Protein Receptors, Type I
Bone Morphogenetic Protein Receptors, Type II
Cumulus Cells
Female
Fertilization in Vitro
Gene Expression Regulation, Developmental
Humans
Middle Aged
Oocytes
Ovarian Follicle
Protein-Serine-Threonine Kinases
Receptor Protein-Tyrosine Kinases
Receptor, Transforming Growth Factor-beta Type I
Receptors, Transforming Growth Factor beta
Reproductive Techniques, Assisted
Portugal
title_short Age-related expression of TGF beta family receptors in human cumulus oophorus cells
title_full Age-related expression of TGF beta family receptors in human cumulus oophorus cells
title_fullStr Age-related expression of TGF beta family receptors in human cumulus oophorus cells
title_full_unstemmed Age-related expression of TGF beta family receptors in human cumulus oophorus cells
title_sort Age-related expression of TGF beta family receptors in human cumulus oophorus cells
author Ribeiro, A.
author_facet Ribeiro, A.
Freitas, C.
Matos, L.
Gouveia, A.
Gomes, F.
Silva Carvalho, J. L.
Almeida, H.
author_role author
author2 Freitas, C.
Matos, L.
Gouveia, A.
Gomes, F.
Silva Carvalho, J. L.
Almeida, H.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Ribeiro, A.
Freitas, C.
Matos, L.
Gouveia, A.
Gomes, F.
Silva Carvalho, J. L.
Almeida, H.
dc.subject.por.fl_str_mv Adult
Anaplastic Lymphoma Kinase
Bone Morphogenetic Protein Receptors, Type I
Bone Morphogenetic Protein Receptors, Type II
Cumulus Cells
Female
Fertilization in Vitro
Gene Expression Regulation, Developmental
Humans
Middle Aged
Oocytes
Ovarian Follicle
Protein-Serine-Threonine Kinases
Receptor Protein-Tyrosine Kinases
Receptor, Transforming Growth Factor-beta Type I
Receptors, Transforming Growth Factor beta
Reproductive Techniques, Assisted
Portugal
topic Adult
Anaplastic Lymphoma Kinase
Bone Morphogenetic Protein Receptors, Type I
Bone Morphogenetic Protein Receptors, Type II
Cumulus Cells
Female
Fertilization in Vitro
Gene Expression Regulation, Developmental
Humans
Middle Aged
Oocytes
Ovarian Follicle
Protein-Serine-Threonine Kinases
Receptor Protein-Tyrosine Kinases
Receptor, Transforming Growth Factor-beta Type I
Receptors, Transforming Growth Factor beta
Reproductive Techniques, Assisted
Portugal
description During ovarian follicle growth, local cellular interactions are essential for oocyte quality acquisition and successful fertilization. While cumulus cells (CCs) nurture oocytes, they also deliver oocyte-secreted factors (OSFs) that activate receptors on CCs. We hypothesized that disturbance of those interactions contributes to age-related lower reproductive success in women submitted to assisted reproductive technology treatments.
publishDate 2017
dc.date.none.fl_str_mv 2017
2017-01-01T00:00:00Z
2020-07-28T10:15:02Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/33005
url http://hdl.handle.net/10400.26/33005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Ribeiro, A., Freitas, C., Matos, L. et al. Age-related expression f TGF beta family receptors in human cumulus oophorus cells. J Assist Reprod Genet 34, 1121–1129 (2017).
1058-0468 (Print) 1573-7330 (Online)
10.1007/s10815-017-0930-6
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799134906502086656

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