POST-DISSECTION THORACO-ABDOMINAL ANEURYSMS: RESULTS OF OPEN AND ENDOVASCULAR REPAIR

Detalhes bibliográficos
Autor(a) principal: Gouveia e Melo, Ryan
Data de Publicação: 2021
Outros Autores: Campos, Jorge, Garrido, Pedro, Lopes, Alice, Fernandes e Fernandes, Ruy, Silvestre, Luís, Sobrinho, Gonçalo, Ministro, Augusto, Amorim, Pedro, Moutinho, Mariana, Martins, Carlos, Nobre, Ângelo, Fernandes e Fernandes, José, Mendes Pedro, Luís
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.48750/acv.334
Resumo: Introduction/Objectives: Repair of post-dissection thoraco-abdominal aortic aneurysms (PD-TAAA) is a complex challenge. Choosing the correct approach to manage these aneurysms is not straightforward as both open and endovascular strategies are valid. Our aim was to analyze and compare the results of PD-TAAA treated by endovascular or open surgery. Methods: A seven-year (January-2013 and May-2020) single-center retrospective cohort study of patients with PD-TAAA treated by endovascular (group-1) or open (group-2) surgery was conducted. Primary outcome was in-hospital mortality. Secondary outcomes were organ lesion, in-hospital infections, length of stay (LOS), endoleaks, branch occlusions, re-interventions and mortality during follow-up. Results: Twenty-one patients (15-men) were treated: 8 in group-1 and 13 in group-2. The mean age was lower in group-2 [68 (SD:11) versus 48 (SD:12), p=0.004]. Three patients had connective tissue disease (CTD). Group-1 patients had a higher ASA score (p<0.001). In group-1, debranching and TEVAR were performed in 2 patients and custom-made fenestrated/ branched-endografts were used in 6. In group-2, there was one thoracic aorta interposition graft and reconstruction involving the visceral arteries ocurred in 12 patients. Seven cases were operated using the Crawford technique with visceral patch, and branched grafts were used in 3 patients with CTD. Intercostal arteries were revascularized in 5 patients. In-hospital mortality was 12% (1 patient) in group-1 and 15% (2 patients) in group-2, LogRank=0.9. The LOS was longer in group-2 (p=0.033), and there was a tendency for a longer stay in intensive care unit in this group. No difference was observed in spinal cord ischemia, acute kidney injury or re-interventions. There were more post-operative infections in group-2 (12% versus 69%, p = 0.017). During follow-up [median 15 months (IQR:55)], there was no mortality after discharge. In group-1, 14% had type-II-endoleaks, without aneurysmal sac dilation. Branch permeability during follow-up was 100% in group-1 and 95% in group-2, LogRank=0.3. Conclusion: Endovascular and open surgery of PD-TAAA allowed treatment of a wide variety of patients in this cohort. Patients treated by the endovascular surgery were older and had higher surgical risk but without repercussions on the outcomes. Open surgery was associated with longer hospital stay and more postoperative complications.
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spelling POST-DISSECTION THORACO-ABDOMINAL ANEURYSMS: RESULTS OF OPEN AND ENDOVASCULAR REPAIRANEURISMAS TÓRACO-ABDOMINAIS APÓS DISSECÇÃO AÓRTICA: RESULTADOS DO TRATAMENTO ABERTO E ENDOVASCULARaortic dissection;Post-dissection aneurysms;Thoraco-abdominal aneurysmsAneurismas pós-dissecçãodissecção da aortaAneurismas toraco-abdominaisIntroduction/Objectives: Repair of post-dissection thoraco-abdominal aortic aneurysms (PD-TAAA) is a complex challenge. Choosing the correct approach to manage these aneurysms is not straightforward as both open and endovascular strategies are valid. Our aim was to analyze and compare the results of PD-TAAA treated by endovascular or open surgery. Methods: A seven-year (January-2013 and May-2020) single-center retrospective cohort study of patients with PD-TAAA treated by endovascular (group-1) or open (group-2) surgery was conducted. Primary outcome was in-hospital mortality. Secondary outcomes were organ lesion, in-hospital infections, length of stay (LOS), endoleaks, branch occlusions, re-interventions and mortality during follow-up. Results: Twenty-one patients (15-men) were treated: 8 in group-1 and 13 in group-2. The mean age was lower in group-2 [68 (SD:11) versus 48 (SD:12), p=0.004]. Three patients had connective tissue disease (CTD). Group-1 patients had a higher ASA score (p<0.001). In group-1, debranching and TEVAR were performed in 2 patients and custom-made fenestrated/ branched-endografts were used in 6. In group-2, there was one thoracic aorta interposition graft and reconstruction involving the visceral arteries ocurred in 12 patients. Seven cases were operated using the Crawford technique with visceral patch, and branched grafts were used in 3 patients with CTD. Intercostal arteries were revascularized in 5 patients. In-hospital mortality was 12% (1 patient) in group-1 and 15% (2 patients) in group-2, LogRank=0.9. The LOS was longer in group-2 (p=0.033), and there was a tendency for a longer stay in intensive care unit in this group. No difference was observed in spinal cord ischemia, acute kidney injury or re-interventions. There were more post-operative infections in group-2 (12% versus 69%, p = 0.017). During follow-up [median 15 months (IQR:55)], there was no mortality after discharge. In group-1, 14% had type-II-endoleaks, without aneurysmal sac dilation. Branch permeability during follow-up was 100% in group-1 and 95% in group-2, LogRank=0.3. Conclusion: Endovascular and open surgery of PD-TAAA allowed treatment of a wide variety of patients in this cohort. Patients treated by the endovascular surgery were older and had higher surgical risk but without repercussions on the outcomes. Open surgery was associated with longer hospital stay and more postoperative complications.Introdução/Objetivos: Comparar resultados do tratamento de aneurismas aórticos tóraco-abdominais pós-dissecção (AATA-PD) tratados por via endovascular ou aberta. Material e Métodos: Estudo observacional (coorte retrospetiva) dos doentes tratados com AATA-PD por via endovascular (grupo-1) ou aberta (grupo-2) entre Janeiro-2013 e Maio-2020. Outcome primário: mortalidade-hospitalar. Outcomes secundários: lesão de orgão, infeções hospitalares, duração de internamento, endoleaks, oclusões de ramo, re-intervenções e mortalidade no follow-up. Resultados: Trataram-se 21 doentes (15-homens): 8 no grupo-1 e 13 no grupo-2. A idade média foi menor no grupo-2 [68 (DP:11) versus 48 (DP:12), p=0.004]. Três doentes tinham conectivopatia. Os doentes do grupo-1 tinham um score ASA maior (p<0,001). No grupo-1 realizaram-se debranching e TEVAR em 2 doentes e em 6 utilizaram-se endopróteses custom-made com fenestrações/ramos. No grupo-2 realizou-se uma interposição na aorta tóracica e em 12 doentes a reconstrução envolveu as artérias viscerais. Em 7 casos utilizou-se a técnica de Crawford com patch visceral e em 3 (com conetivopatia) utilizaram-se próteses ramificadas. Em 5 doentes revascularizaram-se intercostais. A mortalidade hospitalar foi 12% (1 doente) no grupo-1 e 15% (2 doentes) no grupo-2, LogRank=0.9. O tempo de internamento foi maior no grupo-2 (p=0.033), e houve tendência para uma estadia maior nos cuidados intensivos neste grupo. Não houve diferença em isquemia medular, lesão renal aguda ou re-intervenções. Houve mais infeções pós-operatórias no grupo 2 (12% versus 69%, p= 0.017). Durante o follow-up [mediana 15 meses (ΔIQ:55)], não houve mortalidade após a alta. No grupo-1 a taxa de endoleaks foi 14%, sem crescimento do saco aneurismático. A permeabilidade dos ramos durante o follow-up foi 100% no grupo-1 e 95% no grupo-2, LogRank=0.3. Conclusão: A cirurgia endovascular e aberta de AATA-PD permitiu tratar uma grande variedade de doentes nesta coorte. Os doentes tratados por via endovascular foram mais velhos e com maior risco mas sem repercussão nos outcomes. A cirurgia aberta associou-se a internamento mais longo e mais complicações pós-operatórias.  Sociedade Portuguesa de Angiologia e Cirurgia Vascular2021-03-05T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.48750/acv.334oai:ojs.acvjournal.com:article/334Angiologia e Cirurgia Vascular; Vol. 16 No. 4 (2020): December; 275-284Angiologia e Cirurgia Vascular; Vol. 16 N.º 4 (2020): Dezembro; 275-2842183-00961646-706Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://acvjournal.com/index.php/acv/article/view/334https://doi.org/10.48750/acv.334http://acvjournal.com/index.php/acv/article/view/334/215Copyright (c) 2021 Angiologia e Cirurgia Vascularinfo:eu-repo/semantics/openAccessGouveia e Melo, RyanCampos, JorgeGarrido, PedroLopes, AliceFernandes e Fernandes, RuySilvestre, LuísSobrinho, GonçaloMinistro, AugustoAmorim, PedroMoutinho, MarianaMartins, CarlosNobre, ÂngeloFernandes e Fernandes, JoséMendes Pedro, Luís2022-05-23T15:10:10Zoai:ojs.acvjournal.com:article/334Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T14:57:41.625630Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv POST-DISSECTION THORACO-ABDOMINAL ANEURYSMS: RESULTS OF OPEN AND ENDOVASCULAR REPAIR
ANEURISMAS TÓRACO-ABDOMINAIS APÓS DISSECÇÃO AÓRTICA: RESULTADOS DO TRATAMENTO ABERTO E ENDOVASCULAR
title POST-DISSECTION THORACO-ABDOMINAL ANEURYSMS: RESULTS OF OPEN AND ENDOVASCULAR REPAIR
spellingShingle POST-DISSECTION THORACO-ABDOMINAL ANEURYSMS: RESULTS OF OPEN AND ENDOVASCULAR REPAIR
Gouveia e Melo, Ryan
aortic dissection;
Post-dissection aneurysms;
Thoraco-abdominal aneurysms
Aneurismas pós-dissecção
dissecção da aorta
Aneurismas toraco-abdominais
title_short POST-DISSECTION THORACO-ABDOMINAL ANEURYSMS: RESULTS OF OPEN AND ENDOVASCULAR REPAIR
title_full POST-DISSECTION THORACO-ABDOMINAL ANEURYSMS: RESULTS OF OPEN AND ENDOVASCULAR REPAIR
title_fullStr POST-DISSECTION THORACO-ABDOMINAL ANEURYSMS: RESULTS OF OPEN AND ENDOVASCULAR REPAIR
title_full_unstemmed POST-DISSECTION THORACO-ABDOMINAL ANEURYSMS: RESULTS OF OPEN AND ENDOVASCULAR REPAIR
title_sort POST-DISSECTION THORACO-ABDOMINAL ANEURYSMS: RESULTS OF OPEN AND ENDOVASCULAR REPAIR
author Gouveia e Melo, Ryan
author_facet Gouveia e Melo, Ryan
Campos, Jorge
Garrido, Pedro
Lopes, Alice
Fernandes e Fernandes, Ruy
Silvestre, Luís
Sobrinho, Gonçalo
Ministro, Augusto
Amorim, Pedro
Moutinho, Mariana
Martins, Carlos
Nobre, Ângelo
Fernandes e Fernandes, José
Mendes Pedro, Luís
author_role author
author2 Campos, Jorge
Garrido, Pedro
Lopes, Alice
Fernandes e Fernandes, Ruy
Silvestre, Luís
Sobrinho, Gonçalo
Ministro, Augusto
Amorim, Pedro
Moutinho, Mariana
Martins, Carlos
Nobre, Ângelo
Fernandes e Fernandes, José
Mendes Pedro, Luís
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Gouveia e Melo, Ryan
Campos, Jorge
Garrido, Pedro
Lopes, Alice
Fernandes e Fernandes, Ruy
Silvestre, Luís
Sobrinho, Gonçalo
Ministro, Augusto
Amorim, Pedro
Moutinho, Mariana
Martins, Carlos
Nobre, Ângelo
Fernandes e Fernandes, José
Mendes Pedro, Luís
dc.subject.por.fl_str_mv aortic dissection;
Post-dissection aneurysms;
Thoraco-abdominal aneurysms
Aneurismas pós-dissecção
dissecção da aorta
Aneurismas toraco-abdominais
topic aortic dissection;
Post-dissection aneurysms;
Thoraco-abdominal aneurysms
Aneurismas pós-dissecção
dissecção da aorta
Aneurismas toraco-abdominais
description Introduction/Objectives: Repair of post-dissection thoraco-abdominal aortic aneurysms (PD-TAAA) is a complex challenge. Choosing the correct approach to manage these aneurysms is not straightforward as both open and endovascular strategies are valid. Our aim was to analyze and compare the results of PD-TAAA treated by endovascular or open surgery. Methods: A seven-year (January-2013 and May-2020) single-center retrospective cohort study of patients with PD-TAAA treated by endovascular (group-1) or open (group-2) surgery was conducted. Primary outcome was in-hospital mortality. Secondary outcomes were organ lesion, in-hospital infections, length of stay (LOS), endoleaks, branch occlusions, re-interventions and mortality during follow-up. Results: Twenty-one patients (15-men) were treated: 8 in group-1 and 13 in group-2. The mean age was lower in group-2 [68 (SD:11) versus 48 (SD:12), p=0.004]. Three patients had connective tissue disease (CTD). Group-1 patients had a higher ASA score (p<0.001). In group-1, debranching and TEVAR were performed in 2 patients and custom-made fenestrated/ branched-endografts were used in 6. In group-2, there was one thoracic aorta interposition graft and reconstruction involving the visceral arteries ocurred in 12 patients. Seven cases were operated using the Crawford technique with visceral patch, and branched grafts were used in 3 patients with CTD. Intercostal arteries were revascularized in 5 patients. In-hospital mortality was 12% (1 patient) in group-1 and 15% (2 patients) in group-2, LogRank=0.9. The LOS was longer in group-2 (p=0.033), and there was a tendency for a longer stay in intensive care unit in this group. No difference was observed in spinal cord ischemia, acute kidney injury or re-interventions. There were more post-operative infections in group-2 (12% versus 69%, p = 0.017). During follow-up [median 15 months (IQR:55)], there was no mortality after discharge. In group-1, 14% had type-II-endoleaks, without aneurysmal sac dilation. Branch permeability during follow-up was 100% in group-1 and 95% in group-2, LogRank=0.3. Conclusion: Endovascular and open surgery of PD-TAAA allowed treatment of a wide variety of patients in this cohort. Patients treated by the endovascular surgery were older and had higher surgical risk but without repercussions on the outcomes. Open surgery was associated with longer hospital stay and more postoperative complications.
publishDate 2021
dc.date.none.fl_str_mv 2021-03-05T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://doi.org/10.48750/acv.334
oai:ojs.acvjournal.com:article/334
url https://doi.org/10.48750/acv.334
identifier_str_mv oai:ojs.acvjournal.com:article/334
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv http://acvjournal.com/index.php/acv/article/view/334
https://doi.org/10.48750/acv.334
http://acvjournal.com/index.php/acv/article/view/334/215
dc.rights.driver.fl_str_mv Copyright (c) 2021 Angiologia e Cirurgia Vascular
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2021 Angiologia e Cirurgia Vascular
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
dc.source.none.fl_str_mv Angiologia e Cirurgia Vascular; Vol. 16 No. 4 (2020): December; 275-284
Angiologia e Cirurgia Vascular; Vol. 16 N.º 4 (2020): Dezembro; 275-284
2183-0096
1646-706X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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