Late Clearance of Chronic Hepatitis C: A Rare Case Report

• Autor(a) principal: Coutinho Soares, Leonor
• Data de Publicação: 2023
• Outros Autores: Rebelo Matos, André, Mello Vieira, Marta, Cruz, Rita, Moreira, Laura, Azevedo, Luísa
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• DOI: 10.24950/rspmi.1087
• Texto Completo: https://doi.org/10.24950/rspmi.1087
• topic: Anticorpos Neutralizantes; Hepatite C Crónica; Hepatite C; Antibodies, Neutralizing; Hepatitis C; Hepatitis C, Chronic

Hepatitis C virus (HCV) infection is one of the leading causes of chronic liver disease worldwide. The long-term impact of HCV infection is highly variable, from minimal changes to extensive fibrosis and cirrhosis, with or without progression to hepatocellular carcinoma. Spontaneous viral clearance of HCV, defined by sustained undetectable serum viral load concentrations, occurs in about 20%-25% of those infected, usually within the first 6 to 12 months after primary infection. We present the case of a patient admitted to an internal medicine ward with a likely chronic HCV infection, without epidemiological context, but with established liver disease and cirrhosis, who developed a process of spontaneous elimination, due to acute Epstein Barr virus infection.