nodeML - Towards reproducible ML in federated environments

• Autor(a) principal: Silva, Edgar Simão da Mota e
• Data de Publicação: 2022
• Tipo de documento: Dissertação
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://hdl.handle.net/10400.22/21438
• topic: Federated learning; Decentralization; Machine Learning; Immunology; Immunotherapy; Genetics

Advances and increasing interest in AI (Artificial Intelligence) in the field of health have created novel issues, namely explainability and reproducibility of ML (Machine Learning) models. In addition, while the training of ML models traditionally favors a centralized approach, scalability and privacy issues seem to lead towards a distributed one. The latter poses challenges to ML algorithms and the efficacy of learning itself. Reproducing ML models poses several challenges arising from the intrinsic variability of the models themselves and the environment where they are trained. This problem is aggravated by their lack of standardization and common terminology. The main goal of this work is to conceptualize and prototype a framework to train, evaluate and describe ML models, in a decentralized way, over immunogenetics datasets. This framework will promote model reproducibility and comparability, as well as its adaptability. This work will start by implementing a federated/decentralized training framework over existing ML pipelines. Then, it will be possible to list and select potential dataset sources, aiming to provide an easy path to model adaptation and optimization.