The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell Lines

Detalhes bibliográficos
Autor(a) principal: Quintela Vieira, Ana Filipa
Data de Publicação: 2020
Outros Autores: Marques-Magalhães, Ângela, Miranda-Gonçalves, Vera, Ferraz, Ricardo, Vieira, Mónica, Prudêncio, Cristina, Jerónimo, Carmen, Silva, Regina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.22/16835
Resumo: Breast (BrCa) and prostate (PCa) cancers are the most common malignancies in women and men, respectively. The available therapeutic options for these tumors are still not curative and have severe side e↵ects. Therefore, there is an urgent need for more e↵ective antineoplastic agents. Herein, BrCa, PCa, and benign cell lines were treated with two ionic liquids and two quinoxalines and functional experiments were performed—namely cell viability, apoptosis, cytotoxicity, and colony formation assays.
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spelling The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell LinesBreast cancerProstate cancerIonic liquidsQuinoxalinesTreatmentBreast (BrCa) and prostate (PCa) cancers are the most common malignancies in women and men, respectively. The available therapeutic options for these tumors are still not curative and have severe side e↵ects. Therefore, there is an urgent need for more e↵ective antineoplastic agents. Herein, BrCa, PCa, and benign cell lines were treated with two ionic liquids and two quinoxalines and functional experiments were performed—namely cell viability, apoptosis, cytotoxicity, and colony formation assays.MDPIRepositório Científico do Instituto Politécnico do PortoQuintela Vieira, Ana FilipaMarques-Magalhães, ÂngelaMiranda-Gonçalves, VeraFerraz, RicardoVieira, MónicaPrudêncio, CristinaJerónimo, CarmenSilva, Regina2021-02-02T16:45:14Z2020-12-162020-12-16T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/16835engVieira, F. Q., Marques-Magalhães, Â., Miranda-Gonçalves, V., Ferraz, R., Vieira, M., Prudêncio, C., . . . Silva, R. A. (2020). The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell Lines. International Journal of Molecular Sciences, 21(24). doi:10.3390/ijms2124958410.3390/ijms21249584info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-13T13:04:47Zoai:recipp.ipp.pt:10400.22/16835Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:36:29.257744Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell Lines
title The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell Lines
spellingShingle The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell Lines
Quintela Vieira, Ana Filipa
Breast cancer
Prostate cancer
Ionic liquids
Quinoxalines
Treatment
title_short The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell Lines
title_full The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell Lines
title_fullStr The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell Lines
title_full_unstemmed The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell Lines
title_sort The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell Lines
author Quintela Vieira, Ana Filipa
author_facet Quintela Vieira, Ana Filipa
Marques-Magalhães, Ângela
Miranda-Gonçalves, Vera
Ferraz, Ricardo
Vieira, Mónica
Prudêncio, Cristina
Jerónimo, Carmen
Silva, Regina
author_role author
author2 Marques-Magalhães, Ângela
Miranda-Gonçalves, Vera
Ferraz, Ricardo
Vieira, Mónica
Prudêncio, Cristina
Jerónimo, Carmen
Silva, Regina
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Politécnico do Porto
dc.contributor.author.fl_str_mv Quintela Vieira, Ana Filipa
Marques-Magalhães, Ângela
Miranda-Gonçalves, Vera
Ferraz, Ricardo
Vieira, Mónica
Prudêncio, Cristina
Jerónimo, Carmen
Silva, Regina
dc.subject.por.fl_str_mv Breast cancer
Prostate cancer
Ionic liquids
Quinoxalines
Treatment
topic Breast cancer
Prostate cancer
Ionic liquids
Quinoxalines
Treatment
description Breast (BrCa) and prostate (PCa) cancers are the most common malignancies in women and men, respectively. The available therapeutic options for these tumors are still not curative and have severe side e↵ects. Therefore, there is an urgent need for more e↵ective antineoplastic agents. Herein, BrCa, PCa, and benign cell lines were treated with two ionic liquids and two quinoxalines and functional experiments were performed—namely cell viability, apoptosis, cytotoxicity, and colony formation assays.
publishDate 2020
dc.date.none.fl_str_mv 2020-12-16
2020-12-16T00:00:00Z
2021-02-02T16:45:14Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/16835
url http://hdl.handle.net/10400.22/16835
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Vieira, F. Q., Marques-Magalhães, Â., Miranda-Gonçalves, V., Ferraz, R., Vieira, M., Prudêncio, C., . . . Silva, R. A. (2020). The Impact of [C16Pyr][Amp] on the Aggressiveness in Breast and Prostate Cancer Cell Lines. International Journal of Molecular Sciences, 21(24). doi:10.3390/ijms21249584
10.3390/ijms21249584
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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