Prevalent species in vascular access medical device-associated infections
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Tipo de documento: | Dissertação |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10773/30961 |
Resumo: | Central venous Catheters (CVCs) and Peripheral venous Catheters (PVCs) break the skin barriers, opening a door to microorganisms that potentially cause bloodstream infections (BSIs).This study aimed to infer about the epidemiology of species associated with the use of CVCs and the design of a protocol for the surveillance of PVC tip bacterial colonization at Centro Hospitalar do Baixo Vouga. The rolling of catheter tips was performed using the Maki technique, microorganisms were identified using MALDI-TOF MS and the antimicrobial susceptibility test by disk diffusion method was performed. The majority of patients in this study were men over 60 years old. 39% of the analysed CVC tips tested positive for the presence of microorganisms, of which most were Gram-positive bacteria and only 15% of the total isolated microorganisms were considered the source of a BSI-associated with CVC use. Of the analysed PVC tips, only a small portion had a positive result for the presence of microorganisms, with Staphylococcus epidermidis being the most frequent one. Methicillin-resistant S. epidermidis and S. aureus (MRSE/MRSA) were also observed. The presence of microorganisms even though they belong to the human skin microbiota, in catheter tips is, in itself, a risk for the development of BSIs associated with catheter use. |
id |
RCAP_38c90e3943065e05ad157bd7adc728cd |
---|---|
oai_identifier_str |
oai:ria.ua.pt:10773/30961 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Prevalent species in vascular access medical device-associated infectionsVascular access medical devicesCathetersBloodstream infectionsNosocomial infectionsEpidemiologyStaphylococcus sppCentral venous Catheters (CVCs) and Peripheral venous Catheters (PVCs) break the skin barriers, opening a door to microorganisms that potentially cause bloodstream infections (BSIs).This study aimed to infer about the epidemiology of species associated with the use of CVCs and the design of a protocol for the surveillance of PVC tip bacterial colonization at Centro Hospitalar do Baixo Vouga. The rolling of catheter tips was performed using the Maki technique, microorganisms were identified using MALDI-TOF MS and the antimicrobial susceptibility test by disk diffusion method was performed. The majority of patients in this study were men over 60 years old. 39% of the analysed CVC tips tested positive for the presence of microorganisms, of which most were Gram-positive bacteria and only 15% of the total isolated microorganisms were considered the source of a BSI-associated with CVC use. Of the analysed PVC tips, only a small portion had a positive result for the presence of microorganisms, with Staphylococcus epidermidis being the most frequent one. Methicillin-resistant S. epidermidis and S. aureus (MRSE/MRSA) were also observed. The presence of microorganisms even though they belong to the human skin microbiota, in catheter tips is, in itself, a risk for the development of BSIs associated with catheter use.Os cateteres venosos centrais (CVCs) e os cateteres venosos periféricos (CVPs) quebram a barreira da pele, abrindo uma porta a microrganismos potencialmente causadores de infeções da corrente sanguínea (ICS). Este estudo teve como objetivos, inferir sobre a epidemiologia de espécies associadas ao uso de CVCs e o desenho de um protocolo para a vigilância da colonização bacteriana de CVPs no Centro Hospitalar do Baixo Vouga. Foi feito o rolamento de pontas de cateter através da técnica de Maki, identificação de microrganismos através de MALDI-TOF MS e o teste de suscetibilidade a antimicrobianos pelo método de difusão em disco. A maioria dos doentes deste estudo são homens com idade superior a 60 anos. 39% das pontas de CVC analisadas, testaram positivo à presença de microrganismos, dos quais a maioria eram bactérias de Gram-positivo e apenas 15% do total de isolados foram considerados causadores de ICS associada ao uso de CVC. Das pontas de CVP analisadas apenas uma pequena porção teve um resultado positivo para a presença de microrganismos, sendo Staphylococcus epidermidis o microrganismo mais frequente. Observou-se ainda a presença de espécies de S. epidermidis e S. aureus resistentes à meticilina (MRSE/MRSA). A presença de microrganismos, ainda que pertencentes ao microbiota da pele humana, em pontas de cateter é, por si só, um risco para o desenvolvimento de ICS associadas ao uso de cateter.2023-03-10T00:00:00Z2021-02-25T00:00:00Z2021-02-25info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10773/30961engMachado, Carolina de Matos Santos Coimbrainfo:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-22T11:59:51Zoai:ria.ua.pt:10773/30961Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:02:58.419895Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Prevalent species in vascular access medical device-associated infections |
title |
Prevalent species in vascular access medical device-associated infections |
spellingShingle |
Prevalent species in vascular access medical device-associated infections Machado, Carolina de Matos Santos Coimbra Vascular access medical devices Catheters Bloodstream infections Nosocomial infections Epidemiology Staphylococcus spp |
title_short |
Prevalent species in vascular access medical device-associated infections |
title_full |
Prevalent species in vascular access medical device-associated infections |
title_fullStr |
Prevalent species in vascular access medical device-associated infections |
title_full_unstemmed |
Prevalent species in vascular access medical device-associated infections |
title_sort |
Prevalent species in vascular access medical device-associated infections |
author |
Machado, Carolina de Matos Santos Coimbra |
author_facet |
Machado, Carolina de Matos Santos Coimbra |
author_role |
author |
dc.contributor.author.fl_str_mv |
Machado, Carolina de Matos Santos Coimbra |
dc.subject.por.fl_str_mv |
Vascular access medical devices Catheters Bloodstream infections Nosocomial infections Epidemiology Staphylococcus spp |
topic |
Vascular access medical devices Catheters Bloodstream infections Nosocomial infections Epidemiology Staphylococcus spp |
description |
Central venous Catheters (CVCs) and Peripheral venous Catheters (PVCs) break the skin barriers, opening a door to microorganisms that potentially cause bloodstream infections (BSIs).This study aimed to infer about the epidemiology of species associated with the use of CVCs and the design of a protocol for the surveillance of PVC tip bacterial colonization at Centro Hospitalar do Baixo Vouga. The rolling of catheter tips was performed using the Maki technique, microorganisms were identified using MALDI-TOF MS and the antimicrobial susceptibility test by disk diffusion method was performed. The majority of patients in this study were men over 60 years old. 39% of the analysed CVC tips tested positive for the presence of microorganisms, of which most were Gram-positive bacteria and only 15% of the total isolated microorganisms were considered the source of a BSI-associated with CVC use. Of the analysed PVC tips, only a small portion had a positive result for the presence of microorganisms, with Staphylococcus epidermidis being the most frequent one. Methicillin-resistant S. epidermidis and S. aureus (MRSE/MRSA) were also observed. The presence of microorganisms even though they belong to the human skin microbiota, in catheter tips is, in itself, a risk for the development of BSIs associated with catheter use. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-02-25T00:00:00Z 2021-02-25 2023-03-10T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10773/30961 |
url |
http://hdl.handle.net/10773/30961 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/embargoedAccess |
eu_rights_str_mv |
embargoedAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799137684788084736 |