Unveiling the incidences and trends of the neglected zoonosis cystic echinococcosis in Europe: a systematic review from the MEmE project
| Autor(a) principal: | |
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| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10400.18/8392 |
Resumo: | Review |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Unveiling the incidences and trends of the neglected zoonosis cystic echinococcosis in Europe: a systematic review from the MEmE projectEchinococcosisCystic EchinococcosisZoonosis CysticEuropeMEmE projectInfecções Sistémicas e ZoonosesReviewThe neglected zoonosis cystic echinococcosis affects mainly pastoral and rural communities in both low-income and upper-middle-income countries. In Europe, it should be regarded as an orphan and rare disease. Although human cystic echinococcosis is a notifiable parasitic infectious disease in most European countries, in practice it is largely under-reported by national health systems. To fill this gap, we extracted data on the number, incidence, and trend of human cases in Europe through a systematic review approach, using both the scientific and grey literature and accounting for the period of publication from 1997 to 2021. The highest number of possible human cases at the national level was calculated from various data sources to generate a descriptive model of human cystic echinococcosis in Europe. We identified 64 745 human cystic echinococcosis cases from 40 European countries. The mean annual incidence from 1997 to 2020 throughout Europe was 0·64 cases per 100 000 people and in EU member states was 0·50 cases per 100 000 people. Based on incidence rates and trends detected in this study, the current epicentre of cystic echinococcosis in Europe is in the southeastern European countries, whereas historical endemic European Mediterranean countries have recorded a decrease in the number of cases over the time.Key messages: - This study aims to shed light on the unrecognised incidence of cystic echinococcosis in Europe, unveiling its epidemiological effect by providing a quantitative measure of number, incidence, and trends of human cases documented within the period 1997–2021; - Since human cystic echinococcosis cases are generally under-reported and data have uncertainty (partly due to misdiagnosis), data provided in this study should be considered as a conservative estimate of the real impact of this zoonotic infection historically occurring in Europe; - For the years 2017–19, we identified a total number of cystic echinococcosis cases four-fold higher than for The European Surveillance System (TESSy) data; - Decreasing trends have been recorded in most southern Mediterranean and some eastern European countries, where cystic echinococcosis has traditionally been highly prevalent; - Increasing trends have been identified in some eastern and southeastern European countries but, unexpectedly, also in most non-endemic countries of northern and western Europe; - Based on incidence and trends from 2017–19, the current epicentre of cystic echinococcosis in Europe is represented by the Balkan Peninsula; - Cystic echinococcosis in Europe remains a relevant public health issue and findings from this study should be used to support the planning of surveillance and control programmes in Europe according to the WHO 2021–2030 roadmap for neglected tropical diseases.This research was funded by the MEmE project from the EU’s Horizon 2020 Research and Innovation programme under grant agreement number 773830: One Health European Joint Programme. This work was also partially supported by research funding (grant PRG1209) from the Estonian Ministry of Education and ResearchElsevierRepositório Científico do Instituto Nacional de SaúdeCasulli, AdrianoAbela-Ridder, BernadettePetrone, DanieleFabiani, MassimoBobić, BrankoCarmena, DavidŠoba, BarbaraZerem, EnverGargaté, Maria JoãoKuzmanovska, GordanaCalomfirescu, CristianRainova, IskraSotiraki, SmaragdaLungu, VeraDezsényi, BalázsHerrador, ZaidaKaramon, JacekMaksimov, PavloOksanen, AnttiMillon, LaurenceSviben, MarioShkjezi, RenataGjoni, ValbonaAkshija, IlirSaarma, UrmasTorgerson, PaulŠnábel, ViliamAntolová, DanielaMuhovic, DamirBesim, HasanChereau, FannyBelhassen García, MoncefChappuis, FrançoisGloor, SeverinStoeckle, MarcelMüllhaupt, BeatManno, ValerioSantoro, AzzurraSantolamazza, Federica2022-12-12T12:24:10Z2022-11-222022-11-22T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/8392engLancet Infect Dis. 2022 Nov 22;S1473-3099(22)00638-7. doi: 10.1016/S1473-3099(22)00638-7. Online ahead of print. Review1474-445710.1016/S1473-3099(22)00638-7info:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:42:33Zoai:repositorio.insa.pt:10400.18/8392Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:43:03.154066Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Unveiling the incidences and trends of the neglected zoonosis cystic echinococcosis in Europe: a systematic review from the MEmE project |
| title |
Unveiling the incidences and trends of the neglected zoonosis cystic echinococcosis in Europe: a systematic review from the MEmE project |
| spellingShingle |
Unveiling the incidences and trends of the neglected zoonosis cystic echinococcosis in Europe: a systematic review from the MEmE project Casulli, Adriano Echinococcosis Cystic Echinococcosis Zoonosis Cystic Europe MEmE project Infecções Sistémicas e Zoonoses |
| title_short |
Unveiling the incidences and trends of the neglected zoonosis cystic echinococcosis in Europe: a systematic review from the MEmE project |
| title_full |
Unveiling the incidences and trends of the neglected zoonosis cystic echinococcosis in Europe: a systematic review from the MEmE project |
| title_fullStr |
Unveiling the incidences and trends of the neglected zoonosis cystic echinococcosis in Europe: a systematic review from the MEmE project |
| title_full_unstemmed |
Unveiling the incidences and trends of the neglected zoonosis cystic echinococcosis in Europe: a systematic review from the MEmE project |
| title_sort |
Unveiling the incidences and trends of the neglected zoonosis cystic echinococcosis in Europe: a systematic review from the MEmE project |
| author |
Casulli, Adriano |
| author_facet |
Casulli, Adriano Abela-Ridder, Bernadette Petrone, Daniele Fabiani, Massimo Bobić, Branko Carmena, David Šoba, Barbara Zerem, Enver Gargaté, Maria João Kuzmanovska, Gordana Calomfirescu, Cristian Rainova, Iskra Sotiraki, Smaragda Lungu, Vera Dezsényi, Balázs Herrador, Zaida Karamon, Jacek Maksimov, Pavlo Oksanen, Antti Millon, Laurence Sviben, Mario Shkjezi, Renata Gjoni, Valbona Akshija, Ilir Saarma, Urmas Torgerson, Paul Šnábel, Viliam Antolová, Daniela Muhovic, Damir Besim, Hasan Chereau, Fanny Belhassen García, Moncef Chappuis, François Gloor, Severin Stoeckle, Marcel Müllhaupt, Beat Manno, Valerio Santoro, Azzurra Santolamazza, Federica |
| author_role |
author |
| author2 |
Abela-Ridder, Bernadette Petrone, Daniele Fabiani, Massimo Bobić, Branko Carmena, David Šoba, Barbara Zerem, Enver Gargaté, Maria João Kuzmanovska, Gordana Calomfirescu, Cristian Rainova, Iskra Sotiraki, Smaragda Lungu, Vera Dezsényi, Balázs Herrador, Zaida Karamon, Jacek Maksimov, Pavlo Oksanen, Antti Millon, Laurence Sviben, Mario Shkjezi, Renata Gjoni, Valbona Akshija, Ilir Saarma, Urmas Torgerson, Paul Šnábel, Viliam Antolová, Daniela Muhovic, Damir Besim, Hasan Chereau, Fanny Belhassen García, Moncef Chappuis, François Gloor, Severin Stoeckle, Marcel Müllhaupt, Beat Manno, Valerio Santoro, Azzurra Santolamazza, Federica |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Nacional de Saúde |
| dc.contributor.author.fl_str_mv |
Casulli, Adriano Abela-Ridder, Bernadette Petrone, Daniele Fabiani, Massimo Bobić, Branko Carmena, David Šoba, Barbara Zerem, Enver Gargaté, Maria João Kuzmanovska, Gordana Calomfirescu, Cristian Rainova, Iskra Sotiraki, Smaragda Lungu, Vera Dezsényi, Balázs Herrador, Zaida Karamon, Jacek Maksimov, Pavlo Oksanen, Antti Millon, Laurence Sviben, Mario Shkjezi, Renata Gjoni, Valbona Akshija, Ilir Saarma, Urmas Torgerson, Paul Šnábel, Viliam Antolová, Daniela Muhovic, Damir Besim, Hasan Chereau, Fanny Belhassen García, Moncef Chappuis, François Gloor, Severin Stoeckle, Marcel Müllhaupt, Beat Manno, Valerio Santoro, Azzurra Santolamazza, Federica |
| dc.subject.por.fl_str_mv |
Echinococcosis Cystic Echinococcosis Zoonosis Cystic Europe MEmE project Infecções Sistémicas e Zoonoses |
| topic |
Echinococcosis Cystic Echinococcosis Zoonosis Cystic Europe MEmE project Infecções Sistémicas e Zoonoses |
| description |
Review |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-12-12T12:24:10Z 2022-11-22 2022-11-22T00:00:00Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.18/8392 |
| url |
http://hdl.handle.net/10400.18/8392 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Lancet Infect Dis. 2022 Nov 22;S1473-3099(22)00638-7. doi: 10.1016/S1473-3099(22)00638-7. Online ahead of print. Review 1474-4457 10.1016/S1473-3099(22)00638-7 |
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info:eu-repo/semantics/embargoedAccess |
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embargoedAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
Elsevier |
| publisher.none.fl_str_mv |
Elsevier |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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