Development of Nevirapine resistance in children exposed to the prevention of mother-to-child HIV-1 transmission programme in Maputo, Mozambique

Detalhes bibliográficos
Autor(a) principal: Antunes, Francisco
Data de Publicação: 2015
Outros Autores: Zindoga, Pereira, Gomes, Perpétua, Augusto, Orvalho, Mahumane, Isabel, Veloso, Luís, Valadas, Emília, Camacho, Ricardo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/14897
Resumo: This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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spelling Development of Nevirapine resistance in children exposed to the prevention of mother-to-child HIV-1 transmission programme in Maputo, MozambiqueSingle-dose nevirapineMother-to-child transmissionHIV-1MozambiqueNVP resistanceThis is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited."Background: single-dose nevirapine (sd-NVP) has been the main option for prevention of mother-to-child transmission (PMTCT) of HIV-1 in low-resource settings. However, sd-NVP can induce the selection of HIV-1 resistant mutations in mothers and infants. In Mozambique, there are limited data regarding the profile of NVP resistance associated mutations (RAM) in the context of PMTCT. Objectives: to assess the prevalence and the factors associated with NVP RAM among children born to HIV-1 infected mothers enrolled in the PMTCT programme adopted in Mozambique."PLoSRepositório ComumAntunes, FranciscoZindoga, PereiraGomes, PerpétuaAugusto, OrvalhoMahumane, IsabelVeloso, LuísValadas, EmíliaCamacho, Ricardo2016-09-28T10:38:10Z2015-07-01T00:00:00Z2015-07-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/14897engAntunes F, Zindoga P, Gomes P, Augusto O, Mahumane I, Veloso L, et al. (2015) Development of Nevirapine Resistance in Children Exposed to the Prevention of Mother-to-Child HIV-1 Transmission Programme in Maputo, Mozambique. PLoS ONE 10 (7): e0131994. doi:10.1371/journal.pone.01319941932-620310.1371/journal.pone.0131994info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-10-06T14:52:31Zoai:comum.rcaap.pt:10400.26/14897Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:08:22.552849Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Development of Nevirapine resistance in children exposed to the prevention of mother-to-child HIV-1 transmission programme in Maputo, Mozambique
title Development of Nevirapine resistance in children exposed to the prevention of mother-to-child HIV-1 transmission programme in Maputo, Mozambique
spellingShingle Development of Nevirapine resistance in children exposed to the prevention of mother-to-child HIV-1 transmission programme in Maputo, Mozambique
Antunes, Francisco
Single-dose nevirapine
Mother-to-child transmission
HIV-1
Mozambique
NVP resistance
title_short Development of Nevirapine resistance in children exposed to the prevention of mother-to-child HIV-1 transmission programme in Maputo, Mozambique
title_full Development of Nevirapine resistance in children exposed to the prevention of mother-to-child HIV-1 transmission programme in Maputo, Mozambique
title_fullStr Development of Nevirapine resistance in children exposed to the prevention of mother-to-child HIV-1 transmission programme in Maputo, Mozambique
title_full_unstemmed Development of Nevirapine resistance in children exposed to the prevention of mother-to-child HIV-1 transmission programme in Maputo, Mozambique
title_sort Development of Nevirapine resistance in children exposed to the prevention of mother-to-child HIV-1 transmission programme in Maputo, Mozambique
author Antunes, Francisco
author_facet Antunes, Francisco
Zindoga, Pereira
Gomes, Perpétua
Augusto, Orvalho
Mahumane, Isabel
Veloso, Luís
Valadas, Emília
Camacho, Ricardo
author_role author
author2 Zindoga, Pereira
Gomes, Perpétua
Augusto, Orvalho
Mahumane, Isabel
Veloso, Luís
Valadas, Emília
Camacho, Ricardo
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Antunes, Francisco
Zindoga, Pereira
Gomes, Perpétua
Augusto, Orvalho
Mahumane, Isabel
Veloso, Luís
Valadas, Emília
Camacho, Ricardo
dc.subject.por.fl_str_mv Single-dose nevirapine
Mother-to-child transmission
HIV-1
Mozambique
NVP resistance
topic Single-dose nevirapine
Mother-to-child transmission
HIV-1
Mozambique
NVP resistance
description This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
publishDate 2015
dc.date.none.fl_str_mv 2015-07-01T00:00:00Z
2015-07-01T00:00:00Z
2016-09-28T10:38:10Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/14897
url http://hdl.handle.net/10400.26/14897
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Antunes F, Zindoga P, Gomes P, Augusto O, Mahumane I, Veloso L, et al. (2015) Development of Nevirapine Resistance in Children Exposed to the Prevention of Mother-to-Child HIV-1 Transmission Programme in Maputo, Mozambique. PLoS ONE 10 (7): e0131994. doi:10.1371/journal.pone.0131994
1932-6203
10.1371/journal.pone.0131994
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dc.publisher.none.fl_str_mv PLoS
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