Delayed resolution of vitreomacular traction syndrome following intravitreal injection of ocriplasmin
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.48560/rspo.11824 |
Resumo: | Introduction: Ocriplasmin is the first pharmacological treatment option approved for the treatment of vitreomacular traction (VMT), including those associated with macular holes. Resolution of vitreomacular adhesion is typically observed within 28 days of intravitreal ocriplasmin injection with the vast majority of patients experiencing vitreomacular release within the first 7 days of treatment. Methods: We report two cases of symptomatic VMT, in which we observed delayed VMT release after intravitreal ocriplasmin. Results: One month after treatment, there was only partial release of VMT in both cases. Complete VMT resolution was achieved in 4 and 2 months, respectively, following intravitreal ocriplasmin injection. Conclusions: Our case reports shows that favorable results can be observed long after the 28 days established to achieve the final outcome of ocriplasmin treatment, and this may have been facilitated by the initial release of VMT by ocriplasmin. The description of the present case reports adds to the literature suggesting that longer observation may be needed after intravitreal ocriplasmin. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Delayed resolution of vitreomacular traction syndrome following intravitreal injection of ocriplasminComunicações Curtas e Imagens em OftalmologiaIntroduction: Ocriplasmin is the first pharmacological treatment option approved for the treatment of vitreomacular traction (VMT), including those associated with macular holes. Resolution of vitreomacular adhesion is typically observed within 28 days of intravitreal ocriplasmin injection with the vast majority of patients experiencing vitreomacular release within the first 7 days of treatment. Methods: We report two cases of symptomatic VMT, in which we observed delayed VMT release after intravitreal ocriplasmin. Results: One month after treatment, there was only partial release of VMT in both cases. Complete VMT resolution was achieved in 4 and 2 months, respectively, following intravitreal ocriplasmin injection. Conclusions: Our case reports shows that favorable results can be observed long after the 28 days established to achieve the final outcome of ocriplasmin treatment, and this may have been facilitated by the initial release of VMT by ocriplasmin. The description of the present case reports adds to the literature suggesting that longer observation may be needed after intravitreal ocriplasmin.Ajnet2017-10-31T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/reporthttps://doi.org/10.48560/rspo.11824eng1646-69501646-6950Moreira, JorgeTeixeira, CarlaGonçalves, RitaCoelho, PedroMaio, Tiagoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-22T17:06:03Zoai:ojs.revistas.rcaap.pt:article/11824Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:01:40.186918Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Delayed resolution of vitreomacular traction syndrome following intravitreal injection of ocriplasmin |
title |
Delayed resolution of vitreomacular traction syndrome following intravitreal injection of ocriplasmin |
spellingShingle |
Delayed resolution of vitreomacular traction syndrome following intravitreal injection of ocriplasmin Moreira, Jorge Comunicações Curtas e Imagens em Oftalmologia |
title_short |
Delayed resolution of vitreomacular traction syndrome following intravitreal injection of ocriplasmin |
title_full |
Delayed resolution of vitreomacular traction syndrome following intravitreal injection of ocriplasmin |
title_fullStr |
Delayed resolution of vitreomacular traction syndrome following intravitreal injection of ocriplasmin |
title_full_unstemmed |
Delayed resolution of vitreomacular traction syndrome following intravitreal injection of ocriplasmin |
title_sort |
Delayed resolution of vitreomacular traction syndrome following intravitreal injection of ocriplasmin |
author |
Moreira, Jorge |
author_facet |
Moreira, Jorge Teixeira, Carla Gonçalves, Rita Coelho, Pedro Maio, Tiago |
author_role |
author |
author2 |
Teixeira, Carla Gonçalves, Rita Coelho, Pedro Maio, Tiago |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Moreira, Jorge Teixeira, Carla Gonçalves, Rita Coelho, Pedro Maio, Tiago |
dc.subject.por.fl_str_mv |
Comunicações Curtas e Imagens em Oftalmologia |
topic |
Comunicações Curtas e Imagens em Oftalmologia |
description |
Introduction: Ocriplasmin is the first pharmacological treatment option approved for the treatment of vitreomacular traction (VMT), including those associated with macular holes. Resolution of vitreomacular adhesion is typically observed within 28 days of intravitreal ocriplasmin injection with the vast majority of patients experiencing vitreomacular release within the first 7 days of treatment. Methods: We report two cases of symptomatic VMT, in which we observed delayed VMT release after intravitreal ocriplasmin. Results: One month after treatment, there was only partial release of VMT in both cases. Complete VMT resolution was achieved in 4 and 2 months, respectively, following intravitreal ocriplasmin injection. Conclusions: Our case reports shows that favorable results can be observed long after the 28 days established to achieve the final outcome of ocriplasmin treatment, and this may have been facilitated by the initial release of VMT by ocriplasmin. The description of the present case reports adds to the literature suggesting that longer observation may be needed after intravitreal ocriplasmin. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-10-31T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.48560/rspo.11824 |
url |
https://doi.org/10.48560/rspo.11824 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1646-6950 1646-6950 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Ajnet |
publisher.none.fl_str_mv |
Ajnet |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799130481883611136 |