Comfort and infection control of chitosan-impregnated cotton gauze as wound dressing

Detalhes bibliográficos
Autor(a) principal: Souza, Jefferson M.
Data de Publicação: 2019
Outros Autores: Henriques, Mariana, Teixeira, Maria Pilar Araújo, Fernandes, Margarida Maria Macedo, Fangueiro, Raúl, Zille, Andrea
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/60293
Resumo: The aim of this study was to evaluate the thermo-physiological comfort properties of surgical cotton gauze coated with chitosan (CH) and its effectiveness for the prevention of bacterial colonization. Gauze was coated with CH at mass fractions of 0.50, 0.25, 0.125, 0.10, 0.063 wt% and the friction, flexibility, thermal, moisture management and mechanical properties were evaluated. The best performing gauze in terms of comfort (0.125 wt%) was further evaluated for its ability to inhibit the growth of microorganisms such as bacteria and yeast. Results indicate that the functionalized medical gauze could induce low friction on the wound bed allowing a good degree of moisture and high absorption capacity of wound exudates. Moreover, it shows antimicrobial properties against medical-relevant pathogens. This biofunctional medical gauze demonstrates to deliver an efficient antimicrobial coating and promote the best conditions for maintenance of the wound microenvironment.
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spelling Comfort and infection control of chitosan-impregnated cotton gauze as wound dressingChitosanCelluloseComforAntimicrobialWound dressingTextileComfortScience & TechnologyThe aim of this study was to evaluate the thermo-physiological comfort properties of surgical cotton gauze coated with chitosan (CH) and its effectiveness for the prevention of bacterial colonization. Gauze was coated with CH at mass fractions of 0.50, 0.25, 0.125, 0.10, 0.063 wt% and the friction, flexibility, thermal, moisture management and mechanical properties were evaluated. The best performing gauze in terms of comfort (0.125 wt%) was further evaluated for its ability to inhibit the growth of microorganisms such as bacteria and yeast. Results indicate that the functionalized medical gauze could induce low friction on the wound bed allowing a good degree of moisture and high absorption capacity of wound exudates. Moreover, it shows antimicrobial properties against medical-relevant pathogens. This biofunctional medical gauze demonstrates to deliver an efficient antimicrobial coating and promote the best conditions for maintenance of the wound microenvironment.Z acknowledges funding from FCT - Fundação para a Ciência e a Tecnologia within the scope of the project POCI- 01-0145-FEDER-007136 and UID/CTM/00264. A. Zille also acknowledges financial support of the FCT through an Investigator FCT Research contract (IF/00071/2015). JS acknowledge CAPES Foundation, Ministry of Education of Brazil, Proc. no 8976/13-9 and the Department of Textile Engineering of the University of Minho, Portugal. The work regarding the biological analysis was supported by the Programa Operacional, Fatores de competitividade - COMPETE and by national funds through FCT on the scope of the projects PTDC/SAU-MIC/119069/2010, RECI/EBB-EBI/ 0179/2012 and PEst-OE/EQB/LA0023/2013. PT acknowledges SFRH/BPD/86732/2012 grant. The authors thank the Project BioHealth - Biotechnology and Bioengineering approaches to improve health quality, Ref. NORTE-07-0124-FEDER- 000027, co-funded by the Programa Operacional Regional do Norte (ON.2 - O Novo Norte), QREN, FEDER.info:eu-repo/semantics/publishedVersionSpringer VerlagUniversidade do MinhoSouza, Jefferson M.Henriques, MarianaTeixeira, Maria Pilar AraújoFernandes, Margarida Maria MacedoFangueiro, RaúlZille, Andrea20192019-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/60293eng1229-91971875-005210.1007/s12221-019-9053-2info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:15:21Zoai:repositorium.sdum.uminho.pt:1822/60293Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:07:46.294150Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Comfort and infection control of chitosan-impregnated cotton gauze as wound dressing
title Comfort and infection control of chitosan-impregnated cotton gauze as wound dressing
spellingShingle Comfort and infection control of chitosan-impregnated cotton gauze as wound dressing
Souza, Jefferson M.
Chitosan
Cellulose
Comfor
Antimicrobial
Wound dressing
Textile
Comfort
Science & Technology
title_short Comfort and infection control of chitosan-impregnated cotton gauze as wound dressing
title_full Comfort and infection control of chitosan-impregnated cotton gauze as wound dressing
title_fullStr Comfort and infection control of chitosan-impregnated cotton gauze as wound dressing
title_full_unstemmed Comfort and infection control of chitosan-impregnated cotton gauze as wound dressing
title_sort Comfort and infection control of chitosan-impregnated cotton gauze as wound dressing
author Souza, Jefferson M.
author_facet Souza, Jefferson M.
Henriques, Mariana
Teixeira, Maria Pilar Araújo
Fernandes, Margarida Maria Macedo
Fangueiro, Raúl
Zille, Andrea
author_role author
author2 Henriques, Mariana
Teixeira, Maria Pilar Araújo
Fernandes, Margarida Maria Macedo
Fangueiro, Raúl
Zille, Andrea
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Souza, Jefferson M.
Henriques, Mariana
Teixeira, Maria Pilar Araújo
Fernandes, Margarida Maria Macedo
Fangueiro, Raúl
Zille, Andrea
dc.subject.por.fl_str_mv Chitosan
Cellulose
Comfor
Antimicrobial
Wound dressing
Textile
Comfort
Science & Technology
topic Chitosan
Cellulose
Comfor
Antimicrobial
Wound dressing
Textile
Comfort
Science & Technology
description The aim of this study was to evaluate the thermo-physiological comfort properties of surgical cotton gauze coated with chitosan (CH) and its effectiveness for the prevention of bacterial colonization. Gauze was coated with CH at mass fractions of 0.50, 0.25, 0.125, 0.10, 0.063 wt% and the friction, flexibility, thermal, moisture management and mechanical properties were evaluated. The best performing gauze in terms of comfort (0.125 wt%) was further evaluated for its ability to inhibit the growth of microorganisms such as bacteria and yeast. Results indicate that the functionalized medical gauze could induce low friction on the wound bed allowing a good degree of moisture and high absorption capacity of wound exudates. Moreover, it shows antimicrobial properties against medical-relevant pathogens. This biofunctional medical gauze demonstrates to deliver an efficient antimicrobial coating and promote the best conditions for maintenance of the wound microenvironment.
publishDate 2019
dc.date.none.fl_str_mv 2019
2019-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/60293
url http://hdl.handle.net/1822/60293
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1229-9197
1875-0052
10.1007/s12221-019-9053-2
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer Verlag
publisher.none.fl_str_mv Springer Verlag
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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