Bovine Milk Formula Based on Partial Hydrolysis of Caseins by Bromelain Enzyme : Better Digestibility and Angiotensin-Converting Enzyme-Inhibitory Properties

Detalhes bibliográficos
Autor(a) principal: Medeiros, Vera
Data de Publicação: 2013
Outros Autores: Rainha, Nuno, Paiva, Lisete S., Lima, Elisabete, Baptista, José
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.3/6252
Resumo: A new methodology was developed using bromelain as a proteolytic enzyme for the production of a partially hydrolyzed bovine milk formula, without changing the milk's organoleptic and nutritional properties. This study also revealed that the in vitro angiotensin-converting enzyme inhibition increased in the modified milk as compared with the control sample, showing the highest angiotensin-converting enzyme-inhibitory activity for fractions with molecular weights between 3 and 10 kg mol⁻¹. The Lineweaver-Burk plot revealed that the produced milk formula acted as a non-competitive inhibitor, as determined by high performance liquid chromatography.
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spelling Bovine Milk Formula Based on Partial Hydrolysis of Caseins by Bromelain Enzyme : Better Digestibility and Angiotensin-Converting Enzyme-Inhibitory PropertiesACE-inhibitory ActivityBromelainMilk Protein AllergyPartially Hydrolyzed Bovine Milk FormulaPhysicochemical and Microbiological PropertiesSensory AnalysisRp-Hplc/UvA new methodology was developed using bromelain as a proteolytic enzyme for the production of a partially hydrolyzed bovine milk formula, without changing the milk's organoleptic and nutritional properties. This study also revealed that the in vitro angiotensin-converting enzyme inhibition increased in the modified milk as compared with the control sample, showing the highest angiotensin-converting enzyme-inhibitory activity for fractions with molecular weights between 3 and 10 kg mol⁻¹. The Lineweaver-Burk plot revealed that the produced milk formula acted as a non-competitive inhibitor, as determined by high performance liquid chromatography.The authors are indebted to Uniao de Cooperativas Agricolas de Lacticinios e Produtores de Leite da Ilha de S. Miguel (UNILEITE), Arrifes, Ponta Delgada, Azores, for the milk samples. Financial support for graduate studies (Vera Medeiros) was provided by Azores University, UNILEITE, and the Government of Azores.Taylor & FrancisRepositório da Universidade dos AçoresMedeiros, VeraRainha, NunoPaiva, Lisete S.Lima, ElisabeteBaptista, José2022-03-24T17:01:31Z2013-11-212022-01-28T19:06:06Z2013-11-21T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.3/6252engMedeiros, V., Rainha, N., Paiva, L., Lima, E., & Baptista, J. (2013). Bovine milk formula based on partial hydrolysis of caseins by bromelain enzyme: Better digestibility and angiotensin-converting enzyme-inhibitory properties. “International Journal of Food Properties”, 17(4), 806–817. https://doi.org/10.1080/10942912.2012.6756071094-2912cv-prod-268727610.1080/10942912.2012.6756071532-2386000327187600009info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-12-20T14:34:36Zoai:repositorio.uac.pt:10400.3/6252Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:28:19.762687Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Bovine Milk Formula Based on Partial Hydrolysis of Caseins by Bromelain Enzyme : Better Digestibility and Angiotensin-Converting Enzyme-Inhibitory Properties
title Bovine Milk Formula Based on Partial Hydrolysis of Caseins by Bromelain Enzyme : Better Digestibility and Angiotensin-Converting Enzyme-Inhibitory Properties
spellingShingle Bovine Milk Formula Based on Partial Hydrolysis of Caseins by Bromelain Enzyme : Better Digestibility and Angiotensin-Converting Enzyme-Inhibitory Properties
Medeiros, Vera
ACE-inhibitory Activity
Bromelain
Milk Protein Allergy
Partially Hydrolyzed Bovine Milk Formula
Physicochemical and Microbiological Properties
Sensory Analysis
Rp-Hplc/Uv
title_short Bovine Milk Formula Based on Partial Hydrolysis of Caseins by Bromelain Enzyme : Better Digestibility and Angiotensin-Converting Enzyme-Inhibitory Properties
title_full Bovine Milk Formula Based on Partial Hydrolysis of Caseins by Bromelain Enzyme : Better Digestibility and Angiotensin-Converting Enzyme-Inhibitory Properties
title_fullStr Bovine Milk Formula Based on Partial Hydrolysis of Caseins by Bromelain Enzyme : Better Digestibility and Angiotensin-Converting Enzyme-Inhibitory Properties
title_full_unstemmed Bovine Milk Formula Based on Partial Hydrolysis of Caseins by Bromelain Enzyme : Better Digestibility and Angiotensin-Converting Enzyme-Inhibitory Properties
title_sort Bovine Milk Formula Based on Partial Hydrolysis of Caseins by Bromelain Enzyme : Better Digestibility and Angiotensin-Converting Enzyme-Inhibitory Properties
author Medeiros, Vera
author_facet Medeiros, Vera
Rainha, Nuno
Paiva, Lisete S.
Lima, Elisabete
Baptista, José
author_role author
author2 Rainha, Nuno
Paiva, Lisete S.
Lima, Elisabete
Baptista, José
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade dos Açores
dc.contributor.author.fl_str_mv Medeiros, Vera
Rainha, Nuno
Paiva, Lisete S.
Lima, Elisabete
Baptista, José
dc.subject.por.fl_str_mv ACE-inhibitory Activity
Bromelain
Milk Protein Allergy
Partially Hydrolyzed Bovine Milk Formula
Physicochemical and Microbiological Properties
Sensory Analysis
Rp-Hplc/Uv
topic ACE-inhibitory Activity
Bromelain
Milk Protein Allergy
Partially Hydrolyzed Bovine Milk Formula
Physicochemical and Microbiological Properties
Sensory Analysis
Rp-Hplc/Uv
description A new methodology was developed using bromelain as a proteolytic enzyme for the production of a partially hydrolyzed bovine milk formula, without changing the milk's organoleptic and nutritional properties. This study also revealed that the in vitro angiotensin-converting enzyme inhibition increased in the modified milk as compared with the control sample, showing the highest angiotensin-converting enzyme-inhibitory activity for fractions with molecular weights between 3 and 10 kg mol⁻¹. The Lineweaver-Burk plot revealed that the produced milk formula acted as a non-competitive inhibitor, as determined by high performance liquid chromatography.
publishDate 2013
dc.date.none.fl_str_mv 2013-11-21
2013-11-21T00:00:00Z
2022-03-24T17:01:31Z
2022-01-28T19:06:06Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.3/6252
url http://hdl.handle.net/10400.3/6252
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Medeiros, V., Rainha, N., Paiva, L., Lima, E., & Baptista, J. (2013). Bovine milk formula based on partial hydrolysis of caseins by bromelain enzyme: Better digestibility and angiotensin-converting enzyme-inhibitory properties. “International Journal of Food Properties”, 17(4), 806–817. https://doi.org/10.1080/10942912.2012.675607
1094-2912
cv-prod-2687276
10.1080/10942912.2012.675607
1532-2386
000327187600009
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Taylor & Francis
publisher.none.fl_str_mv Taylor & Francis
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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