Cytomegalovirus infection in kidney transplantation.

Detalhes bibliográficos
Autor(a) principal: Sousa, A
Data de Publicação: 1991
Outros Autores: Magalhães, M M, Sampaio, M J, Correia, A M, da Costa, A G, Pena, E J
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3371
Resumo: 150 patients, subjected to kidney graft transplantation between January 1988 and December 1989, were studied. Mean +/- 95% CL age was 37.5 +/- 2.03 (range 12-69) years. IgG and IgM antibodies levels (ELISA) cytomegalovirus (CMV) were investigated in the donor before organ harvesting and in the kidney recipients on 1st and 21th days and then on the 3rd, 6th and 9th months after transplantation. Patients lacking either donor or 1st day studies were excluded. 133 donor (D) receptor (R) pairs were classified as group 1) D+/R+, 2) D+/R-, 3) D-/R+ e 4) D-/R-. Prevalence, severity of CMV disease and date of diagnosis were studied. Mean time +/- 95% CI of diagnosis after transplantation was 78.4 +/- 15.1 days. Seronegative receptors had a statistically significant higher prevalence of the disease as to seropositive receptors, but not a higher incidence of disease severity. One out of five patients had a serious form of disease. Hiperimmune globulin was used in 15 patients (all serious forms and 3 moderate forms of of disease). No patient died as a result of CMV infection.
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spelling Cytomegalovirus infection in kidney transplantation.Infecção por citomegalovírus no transplante renal.150 patients, subjected to kidney graft transplantation between January 1988 and December 1989, were studied. Mean +/- 95% CL age was 37.5 +/- 2.03 (range 12-69) years. IgG and IgM antibodies levels (ELISA) cytomegalovirus (CMV) were investigated in the donor before organ harvesting and in the kidney recipients on 1st and 21th days and then on the 3rd, 6th and 9th months after transplantation. Patients lacking either donor or 1st day studies were excluded. 133 donor (D) receptor (R) pairs were classified as group 1) D+/R+, 2) D+/R-, 3) D-/R+ e 4) D-/R-. Prevalence, severity of CMV disease and date of diagnosis were studied. Mean time +/- 95% CI of diagnosis after transplantation was 78.4 +/- 15.1 days. Seronegative receptors had a statistically significant higher prevalence of the disease as to seropositive receptors, but not a higher incidence of disease severity. One out of five patients had a serious form of disease. Hiperimmune globulin was used in 15 patients (all serious forms and 3 moderate forms of of disease). No patient died as a result of CMV infection.150 patients, subjected to kidney graft transplantation between January 1988 and December 1989, were studied. Mean +/- 95% CL age was 37.5 +/- 2.03 (range 12-69) years. IgG and IgM antibodies levels (ELISA) cytomegalovirus (CMV) were investigated in the donor before organ harvesting and in the kidney recipients on 1st and 21th days and then on the 3rd, 6th and 9th months after transplantation. Patients lacking either donor or 1st day studies were excluded. 133 donor (D) receptor (R) pairs were classified as group 1) D+/R+, 2) D+/R-, 3) D-/R+ e 4) D-/R-. Prevalence, severity of CMV disease and date of diagnosis were studied. Mean time +/- 95% CI of diagnosis after transplantation was 78.4 +/- 15.1 days. Seronegative receptors had a statistically significant higher prevalence of the disease as to seropositive receptors, but not a higher incidence of disease severity. One out of five patients had a serious form of disease. Hiperimmune globulin was used in 15 patients (all serious forms and 3 moderate forms of of disease). No patient died as a result of CMV infection.Ordem dos Médicos1991-10-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3371oai:ojs.www.actamedicaportuguesa.com:article/3371Acta Médica Portuguesa; Vol. 4 No. 5 (1991): Setembro-Outubro; 231-5Acta Médica Portuguesa; Vol. 4 N.º 5 (1991): Setembro-Outubro; 231-51646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3371https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3371/2697Sousa, AMagalhães, M MSampaio, M JCorreia, A Mda Costa, A GPena, E Jinfo:eu-repo/semantics/openAccess2022-12-20T11:02:09Zoai:ojs.www.actamedicaportuguesa.com:article/3371Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:18:20.356450Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Cytomegalovirus infection in kidney transplantation.
Infecção por citomegalovírus no transplante renal.
title Cytomegalovirus infection in kidney transplantation.
spellingShingle Cytomegalovirus infection in kidney transplantation.
Sousa, A
title_short Cytomegalovirus infection in kidney transplantation.
title_full Cytomegalovirus infection in kidney transplantation.
title_fullStr Cytomegalovirus infection in kidney transplantation.
title_full_unstemmed Cytomegalovirus infection in kidney transplantation.
title_sort Cytomegalovirus infection in kidney transplantation.
author Sousa, A
author_facet Sousa, A
Magalhães, M M
Sampaio, M J
Correia, A M
da Costa, A G
Pena, E J
author_role author
author2 Magalhães, M M
Sampaio, M J
Correia, A M
da Costa, A G
Pena, E J
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Sousa, A
Magalhães, M M
Sampaio, M J
Correia, A M
da Costa, A G
Pena, E J
description 150 patients, subjected to kidney graft transplantation between January 1988 and December 1989, were studied. Mean +/- 95% CL age was 37.5 +/- 2.03 (range 12-69) years. IgG and IgM antibodies levels (ELISA) cytomegalovirus (CMV) were investigated in the donor before organ harvesting and in the kidney recipients on 1st and 21th days and then on the 3rd, 6th and 9th months after transplantation. Patients lacking either donor or 1st day studies were excluded. 133 donor (D) receptor (R) pairs were classified as group 1) D+/R+, 2) D+/R-, 3) D-/R+ e 4) D-/R-. Prevalence, severity of CMV disease and date of diagnosis were studied. Mean time +/- 95% CI of diagnosis after transplantation was 78.4 +/- 15.1 days. Seronegative receptors had a statistically significant higher prevalence of the disease as to seropositive receptors, but not a higher incidence of disease severity. One out of five patients had a serious form of disease. Hiperimmune globulin was used in 15 patients (all serious forms and 3 moderate forms of of disease). No patient died as a result of CMV infection.
publishDate 1991
dc.date.none.fl_str_mv 1991-10-30
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3371/2697
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 4 No. 5 (1991): Setembro-Outubro; 231-5
Acta Médica Portuguesa; Vol. 4 N.º 5 (1991): Setembro-Outubro; 231-5
1646-0758
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