Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide

Detalhes bibliográficos
Autor(a) principal: Santos, A. Sofia
Data de Publicação: 2023
Outros Autores: Ferro, Rita D., Viduedo, Nuno, Maia, Luísa B., Silva, Artur M. S., Marques, M. Manuel B.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/150333
Resumo: The National NMR Facility is supported by FCT, ROTEIRO/0031/2013-PINFRA/22161/2016, co-financed by FEDER through COMPETE2020, POCI, and PORLandFCT through PIDDAC) and CERMAX(022162).
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spelling Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxidebis(indolyl)methanesindoletBuOKradicalsbenzylalcoholsChemistry(all)The National NMR Facility is supported by FCT, ROTEIRO/0031/2013-PINFRA/22161/2016, co-financed by FEDER through COMPETE2020, POCI, and PORLandFCT through PIDDAC) and CERMAX(022162).The indole moiety is an important N-heterocycle found in natural products, and a key structural component of many value-added chemicals including pharmaceuticals. In particular, bis(3-indolyl)methanes (BIMs) are an important subgroup of indoles, composed of two indole units. Herein, we report the development of a simple method to access BIMs derivatives in yields of up to 77 % by exploiting a tBuOK-mediated coupling reaction of indoles and benzyl alcohols.LAQV@REQUIMTEDQ - Departamento de QuímicaRUNSantos, A. SofiaFerro, Rita D.Viduedo, NunoMaia, Luísa B.Silva, Artur M. S.Marques, M. Manuel B.2023-03-10T22:51:11Z2023-012023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article7application/pdfhttp://hdl.handle.net/10362/150333eng2191-1363PURE: 50901166https://doi.org/10.1002/open.202200265info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:32:15Zoai:run.unl.pt:10362/150333Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:54:03.056593Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide
title Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide
spellingShingle Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide
Santos, A. Sofia
bis(indolyl)methanes
indole
tBuOK
radicals
benzylalcohols
Chemistry(all)
title_short Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide
title_full Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide
title_fullStr Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide
title_full_unstemmed Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide
title_sort Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide
author Santos, A. Sofia
author_facet Santos, A. Sofia
Ferro, Rita D.
Viduedo, Nuno
Maia, Luísa B.
Silva, Artur M. S.
Marques, M. Manuel B.
author_role author
author2 Ferro, Rita D.
Viduedo, Nuno
Maia, Luísa B.
Silva, Artur M. S.
Marques, M. Manuel B.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv LAQV@REQUIMTE
DQ - Departamento de Química
RUN
dc.contributor.author.fl_str_mv Santos, A. Sofia
Ferro, Rita D.
Viduedo, Nuno
Maia, Luísa B.
Silva, Artur M. S.
Marques, M. Manuel B.
dc.subject.por.fl_str_mv bis(indolyl)methanes
indole
tBuOK
radicals
benzylalcohols
Chemistry(all)
topic bis(indolyl)methanes
indole
tBuOK
radicals
benzylalcohols
Chemistry(all)
description The National NMR Facility is supported by FCT, ROTEIRO/0031/2013-PINFRA/22161/2016, co-financed by FEDER through COMPETE2020, POCI, and PORLandFCT through PIDDAC) and CERMAX(022162).
publishDate 2023
dc.date.none.fl_str_mv 2023-03-10T22:51:11Z
2023-01
2023-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/150333
url http://hdl.handle.net/10362/150333
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2191-1363
PURE: 50901166
https://doi.org/10.1002/open.202200265
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 7
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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