Bullous Pemphigoid Successfully Treated with Rituximab

Detalhes bibliográficos
Autor(a) principal: Silva, Nuno
Data de Publicação: 2017
Outros Autores: Costa, Andreia, Salvador, Fernando, Serradeiro, Elisa
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812
Resumo: Bullous pemphigoid is an autoimmune disease characterized by subepidermal blister formation. Can be self-limiting but when necessary treatment includes the use of corticosteroids, immunosuppressants, and biological agents. We present the case of a 37 year old patient with a severe and refractory presentation of bullous pemphigoid. After about a month of treatment with various first line drugs and with no response, we chose to start rituximab and clear improvement of the lesions was observed. The authors aim to highlight the usefulness and effectiveness of this drug in this disease.
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spelling Bullous Pemphigoid Successfully Treated with RituximabPenfigoide Bolhoso Tratado com Sucesso com RituximabPemphigoidBullous/drug therapyRituximabPenfigoide Bolhoso/tratamentoRituximabBullous pemphigoid is an autoimmune disease characterized by subepidermal blister formation. Can be self-limiting but when necessary treatment includes the use of corticosteroids, immunosuppressants, and biological agents. We present the case of a 37 year old patient with a severe and refractory presentation of bullous pemphigoid. After about a month of treatment with various first line drugs and with no response, we chose to start rituximab and clear improvement of the lesions was observed. The authors aim to highlight the usefulness and effectiveness of this drug in this disease.O penfigoide bolhoso é uma doença autoimune caracterizada pela formação de bolhas subepidérmicas. Pode ser autolimitada mas quando necessário o tratamento passa pelo uso de corticoides, imunossupressores, e em última linha agentes biológicos. Apresenta-se o caso de um doente de 37 anos com penfigoide bolhoso com uma forma de apresentação grave e refratária. Após cerca de um mês de tratamento com vários fármacos de primeira linha, por ausência de resposta, optou-se por iniciar rituximab com franca melhoria das lesões. Os autores pretendem realçar a utilidade e eficácia deste fármaco nesta patologia.Ordem dos Médicos2017-03-31info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/mswordapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812oai:ojs.www.actamedicaportuguesa.com:article/7812Acta Médica Portuguesa; Vol. 30 No. 3 (2017): March; 243-246Acta Médica Portuguesa; Vol. 30 N.º 3 (2017): Março; 243-2461646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/4974https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/8502https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/8503https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/8504https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/8505https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/8506https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/8507https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/8689https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/8787Direitos de Autor (c) 2017 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessSilva, NunoCosta, AndreiaSalvador, FernandoSerradeiro, Elisa2022-12-20T11:05:20Zoai:ojs.www.actamedicaportuguesa.com:article/7812Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:19:30.192741Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Bullous Pemphigoid Successfully Treated with Rituximab
Penfigoide Bolhoso Tratado com Sucesso com Rituximab
title Bullous Pemphigoid Successfully Treated with Rituximab
spellingShingle Bullous Pemphigoid Successfully Treated with Rituximab
Silva, Nuno
Pemphigoid
Bullous/drug therapy
Rituximab
Penfigoide Bolhoso/tratamento
Rituximab
title_short Bullous Pemphigoid Successfully Treated with Rituximab
title_full Bullous Pemphigoid Successfully Treated with Rituximab
title_fullStr Bullous Pemphigoid Successfully Treated with Rituximab
title_full_unstemmed Bullous Pemphigoid Successfully Treated with Rituximab
title_sort Bullous Pemphigoid Successfully Treated with Rituximab
author Silva, Nuno
author_facet Silva, Nuno
Costa, Andreia
Salvador, Fernando
Serradeiro, Elisa
author_role author
author2 Costa, Andreia
Salvador, Fernando
Serradeiro, Elisa
author2_role author
author
author
dc.contributor.author.fl_str_mv Silva, Nuno
Costa, Andreia
Salvador, Fernando
Serradeiro, Elisa
dc.subject.por.fl_str_mv Pemphigoid
Bullous/drug therapy
Rituximab
Penfigoide Bolhoso/tratamento
Rituximab
topic Pemphigoid
Bullous/drug therapy
Rituximab
Penfigoide Bolhoso/tratamento
Rituximab
description Bullous pemphigoid is an autoimmune disease characterized by subepidermal blister formation. Can be self-limiting but when necessary treatment includes the use of corticosteroids, immunosuppressants, and biological agents. We present the case of a 37 year old patient with a severe and refractory presentation of bullous pemphigoid. After about a month of treatment with various first line drugs and with no response, we chose to start rituximab and clear improvement of the lesions was observed. The authors aim to highlight the usefulness and effectiveness of this drug in this disease.
publishDate 2017
dc.date.none.fl_str_mv 2017-03-31
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dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812
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url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812
identifier_str_mv oai:ojs.www.actamedicaportuguesa.com:article/7812
dc.language.iso.fl_str_mv por
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dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/4974
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/8502
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/8503
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/8504
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/8505
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/8506
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/8507
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/8689
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7812/8787
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2017 Acta Médica Portuguesa
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos de Autor (c) 2017 Acta Médica Portuguesa
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 30 No. 3 (2017): March; 243-246
Acta Médica Portuguesa; Vol. 30 N.º 3 (2017): Março; 243-246
1646-0758
0870-399X
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