Prediction of COVID-19 diagnosis based on openEHR artefacts

Detalhes bibliográficos
Autor(a) principal: Oliveira, Daniela Sofia Rijo
Data de Publicação: 2022
Outros Autores: Ferreira, Diana, Abreu, Nuno, Leuschner, Pedro, Abelha, António, Machado, José Manuel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/1822/86689
Resumo: Nowadays, we are facing the worldwide pandemic caused by COVID-19. The complexity and momentum of monitoring patients infected with this virus calls for the usage of agile and scalable data structure methodologies. OpenEHR is a healthcare standard that is attracting a lot of attention in recent years due to its comprehensive and robust architecture. The importance of an open, standardized and adaptable approach to clinical data lies in extracting value to generate useful knowledge that really can help healthcare professionals make an assertive decision. This importance is even more accentuated when facing a pandemic context. Thus, in this study, a system for tracking symptoms and health conditions of suspected or confirmed SARS-CoV-2 patients from a Portuguese hospital was developed using openEHR. All data on the evolutionary status of patients in home care as well as the results of their COVID-19 test were used to train different ML algorithms, with the aim of developing a predictive model capable of identifying COVID-19 infections according to the severity of symptoms identified by patients. The CRISP-DM methodology was used to conduct this research. The results obtained were promising, with the best model achieving an accuracy of 96.25%, a precision of 99.91%, a sensitivity of 92.58%, a specificity of 99.92%, and an AUC of 0.963, using the Decision Tree algorithm and the Split Validation method. Hence, in the future, after further testing, the predictive model could be implemented in clinical decision support systems.
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spelling Prediction of COVID-19 diagnosis based on openEHR artefactsScience & TechnologyNowadays, we are facing the worldwide pandemic caused by COVID-19. The complexity and momentum of monitoring patients infected with this virus calls for the usage of agile and scalable data structure methodologies. OpenEHR is a healthcare standard that is attracting a lot of attention in recent years due to its comprehensive and robust architecture. The importance of an open, standardized and adaptable approach to clinical data lies in extracting value to generate useful knowledge that really can help healthcare professionals make an assertive decision. This importance is even more accentuated when facing a pandemic context. Thus, in this study, a system for tracking symptoms and health conditions of suspected or confirmed SARS-CoV-2 patients from a Portuguese hospital was developed using openEHR. All data on the evolutionary status of patients in home care as well as the results of their COVID-19 test were used to train different ML algorithms, with the aim of developing a predictive model capable of identifying COVID-19 infections according to the severity of symptoms identified by patients. The CRISP-DM methodology was used to conduct this research. The results obtained were promising, with the best model achieving an accuracy of 96.25%, a precision of 99.91%, a sensitivity of 92.58%, a specificity of 99.92%, and an AUC of 0.963, using the Decision Tree algorithm and the Split Validation method. Hence, in the future, after further testing, the predictive model could be implemented in clinical decision support systems.This work is funded by "FCT-Fundacao para a Ciencia e Tecnologia" within the R &D Units Project Scope: UIDB/00319/2020. D.F. thanks the FundacAo para a Ciencia e Tecnologia (FCT), Portugal for the Grant 2021.06308.BD.Nature ResearchUniversidade do MinhoOliveira, Daniela Sofia RijoFerreira, DianaAbreu, NunoLeuschner, PedroAbelha, AntónioMachado, José Manuel2022-07-222022-07-22T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/86689engOliveira, D., Ferreira, D., Abreu, N., Leuschner, P., Abelha, A., & Machado, J. (2022, July 22). Prediction of COVID-19 diagnosis based on openEHR artefacts. Scientific Reports. Springer Science and Business Media LLC. http://doi.org/10.1038/s41598-022-15968-z2045-232210.1038/s41598-022-15968-z35869091info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-12-23T01:38:36Zoai:repositorium.sdum.uminho.pt:1822/86689Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:33:32.378569Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Prediction of COVID-19 diagnosis based on openEHR artefacts
title Prediction of COVID-19 diagnosis based on openEHR artefacts
spellingShingle Prediction of COVID-19 diagnosis based on openEHR artefacts
Oliveira, Daniela Sofia Rijo
Science & Technology
title_short Prediction of COVID-19 diagnosis based on openEHR artefacts
title_full Prediction of COVID-19 diagnosis based on openEHR artefacts
title_fullStr Prediction of COVID-19 diagnosis based on openEHR artefacts
title_full_unstemmed Prediction of COVID-19 diagnosis based on openEHR artefacts
title_sort Prediction of COVID-19 diagnosis based on openEHR artefacts
author Oliveira, Daniela Sofia Rijo
author_facet Oliveira, Daniela Sofia Rijo
Ferreira, Diana
Abreu, Nuno
Leuschner, Pedro
Abelha, António
Machado, José Manuel
author_role author
author2 Ferreira, Diana
Abreu, Nuno
Leuschner, Pedro
Abelha, António
Machado, José Manuel
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Oliveira, Daniela Sofia Rijo
Ferreira, Diana
Abreu, Nuno
Leuschner, Pedro
Abelha, António
Machado, José Manuel
dc.subject.por.fl_str_mv Science & Technology
topic Science & Technology
description Nowadays, we are facing the worldwide pandemic caused by COVID-19. The complexity and momentum of monitoring patients infected with this virus calls for the usage of agile and scalable data structure methodologies. OpenEHR is a healthcare standard that is attracting a lot of attention in recent years due to its comprehensive and robust architecture. The importance of an open, standardized and adaptable approach to clinical data lies in extracting value to generate useful knowledge that really can help healthcare professionals make an assertive decision. This importance is even more accentuated when facing a pandemic context. Thus, in this study, a system for tracking symptoms and health conditions of suspected or confirmed SARS-CoV-2 patients from a Portuguese hospital was developed using openEHR. All data on the evolutionary status of patients in home care as well as the results of their COVID-19 test were used to train different ML algorithms, with the aim of developing a predictive model capable of identifying COVID-19 infections according to the severity of symptoms identified by patients. The CRISP-DM methodology was used to conduct this research. The results obtained were promising, with the best model achieving an accuracy of 96.25%, a precision of 99.91%, a sensitivity of 92.58%, a specificity of 99.92%, and an AUC of 0.963, using the Decision Tree algorithm and the Split Validation method. Hence, in the future, after further testing, the predictive model could be implemented in clinical decision support systems.
publishDate 2022
dc.date.none.fl_str_mv 2022-07-22
2022-07-22T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/1822/86689
url https://hdl.handle.net/1822/86689
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Oliveira, D., Ferreira, D., Abreu, N., Leuschner, P., Abelha, A., & Machado, J. (2022, July 22). Prediction of COVID-19 diagnosis based on openEHR artefacts. Scientific Reports. Springer Science and Business Media LLC. http://doi.org/10.1038/s41598-022-15968-z
2045-2322
10.1038/s41598-022-15968-z
35869091
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Nature Research
publisher.none.fl_str_mv Nature Research
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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