Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association

Detalhes bibliográficos
Autor(a) principal: Gonçalves, Maria João
Data de Publicação: 2017
Outros Autores: Romão, V. C., Soares-de-Almeida, L., Canhão, Helena, Romeu, J. C., Kutzner, H., Pereira-da-Silva, J. A.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://www.actareumatologica.pt/archive_detail.php?id=216
Resumo: Erythema elevatum diutinum is a rare neutrophilic dermatosis with vasculitis, which presents as persistent, symmetrical, purple or brownish papules and nodules, mainly in the extensor surface of the limbs. We describe a case of erythema elevatum diutinum and polyarthritis as initial manifestations of Crohn's disea se associated spondyloarthritis. A 51-year-old man, from São Tomé e Príncipe, with previous history of treated tuberculosis and chronic hepatitis B infection, was admitted due to 4 months history of polyarthritis, hyperpigmented papules on the extensor surfaces, occasional episodes of bloody mucous diarrhea and significant weight loss. Histology of the skin showed myeloperoxidase positive neutrophilic granulocytes with moderate karyorrhexis, consistent with erythema elevatum diutinum. Colonoscopy showed erosions in sigmoid and rectum. Diagnosis of erythema elevatum diutinum secondary to Crohn's disease with associated peripheral spondyloarthritis was assumed. The patient was treated with prednisolone, sulphasalazine, metronidazole, azathioprine and tenofovir with good clinical response. As erythema elevatum diutinum can be secondary to multiple systemic diseases, including rheumatic diseases and inflammatory bowel disease, being aware and re - cognizing this entity can be of great importance for rheumatologists.
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spelling Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual associationCrohn's disea - seCutaneous vasculitisErythema elevatum diutinumSpondyloarthritisRheumatologySDG 3 - Good Health and Well-beingErythema elevatum diutinum is a rare neutrophilic dermatosis with vasculitis, which presents as persistent, symmetrical, purple or brownish papules and nodules, mainly in the extensor surface of the limbs. We describe a case of erythema elevatum diutinum and polyarthritis as initial manifestations of Crohn's disea se associated spondyloarthritis. A 51-year-old man, from São Tomé e Príncipe, with previous history of treated tuberculosis and chronic hepatitis B infection, was admitted due to 4 months history of polyarthritis, hyperpigmented papules on the extensor surfaces, occasional episodes of bloody mucous diarrhea and significant weight loss. Histology of the skin showed myeloperoxidase positive neutrophilic granulocytes with moderate karyorrhexis, consistent with erythema elevatum diutinum. Colonoscopy showed erosions in sigmoid and rectum. Diagnosis of erythema elevatum diutinum secondary to Crohn's disease with associated peripheral spondyloarthritis was assumed. The patient was treated with prednisolone, sulphasalazine, metronidazole, azathioprine and tenofovir with good clinical response. As erythema elevatum diutinum can be secondary to multiple systemic diseases, including rheumatic diseases and inflammatory bowel disease, being aware and re - cognizing this entity can be of great importance for rheumatologists.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Centro de Estudos de Doenças Crónicas (CEDOC)RUNGonçalves, Maria JoãoRomão, V. C.Soares-de-Almeida, L.Canhão, HelenaRomeu, J. C.Kutzner, H.Pereira-da-Silva, J. A.2018-02-05T23:16:00Z2017-102017-10-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article5application/pdfhttp://www.actareumatologica.pt/archive_detail.php?id=216eng0303-464XPURE: 3537937http://www.actareumatologica.pt/archive_detail.php?id=216info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:16:22Zoai:run.unl.pt:10362/29886Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:29:20.531333Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association
title Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association
spellingShingle Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association
Gonçalves, Maria João
Crohn's disea - se
Cutaneous vasculitis
Erythema elevatum diutinum
Spondyloarthritis
Rheumatology
SDG 3 - Good Health and Well-being
title_short Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association
title_full Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association
title_fullStr Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association
title_full_unstemmed Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association
title_sort Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association
author Gonçalves, Maria João
author_facet Gonçalves, Maria João
Romão, V. C.
Soares-de-Almeida, L.
Canhão, Helena
Romeu, J. C.
Kutzner, H.
Pereira-da-Silva, J. A.
author_role author
author2 Romão, V. C.
Soares-de-Almeida, L.
Canhão, Helena
Romeu, J. C.
Kutzner, H.
Pereira-da-Silva, J. A.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
Centro de Estudos de Doenças Crónicas (CEDOC)
RUN
dc.contributor.author.fl_str_mv Gonçalves, Maria João
Romão, V. C.
Soares-de-Almeida, L.
Canhão, Helena
Romeu, J. C.
Kutzner, H.
Pereira-da-Silva, J. A.
dc.subject.por.fl_str_mv Crohn's disea - se
Cutaneous vasculitis
Erythema elevatum diutinum
Spondyloarthritis
Rheumatology
SDG 3 - Good Health and Well-being
topic Crohn's disea - se
Cutaneous vasculitis
Erythema elevatum diutinum
Spondyloarthritis
Rheumatology
SDG 3 - Good Health and Well-being
description Erythema elevatum diutinum is a rare neutrophilic dermatosis with vasculitis, which presents as persistent, symmetrical, purple or brownish papules and nodules, mainly in the extensor surface of the limbs. We describe a case of erythema elevatum diutinum and polyarthritis as initial manifestations of Crohn's disea se associated spondyloarthritis. A 51-year-old man, from São Tomé e Príncipe, with previous history of treated tuberculosis and chronic hepatitis B infection, was admitted due to 4 months history of polyarthritis, hyperpigmented papules on the extensor surfaces, occasional episodes of bloody mucous diarrhea and significant weight loss. Histology of the skin showed myeloperoxidase positive neutrophilic granulocytes with moderate karyorrhexis, consistent with erythema elevatum diutinum. Colonoscopy showed erosions in sigmoid and rectum. Diagnosis of erythema elevatum diutinum secondary to Crohn's disease with associated peripheral spondyloarthritis was assumed. The patient was treated with prednisolone, sulphasalazine, metronidazole, azathioprine and tenofovir with good clinical response. As erythema elevatum diutinum can be secondary to multiple systemic diseases, including rheumatic diseases and inflammatory bowel disease, being aware and re - cognizing this entity can be of great importance for rheumatologists.
publishDate 2017
dc.date.none.fl_str_mv 2017-10
2017-10-01T00:00:00Z
2018-02-05T23:16:00Z
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