Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://www.actareumatologica.pt/archive_detail.php?id=216 |
Resumo: | Erythema elevatum diutinum is a rare neutrophilic dermatosis with vasculitis, which presents as persistent, symmetrical, purple or brownish papules and nodules, mainly in the extensor surface of the limbs. We describe a case of erythema elevatum diutinum and polyarthritis as initial manifestations of Crohn's disea se associated spondyloarthritis. A 51-year-old man, from São Tomé e Príncipe, with previous history of treated tuberculosis and chronic hepatitis B infection, was admitted due to 4 months history of polyarthritis, hyperpigmented papules on the extensor surfaces, occasional episodes of bloody mucous diarrhea and significant weight loss. Histology of the skin showed myeloperoxidase positive neutrophilic granulocytes with moderate karyorrhexis, consistent with erythema elevatum diutinum. Colonoscopy showed erosions in sigmoid and rectum. Diagnosis of erythema elevatum diutinum secondary to Crohn's disease with associated peripheral spondyloarthritis was assumed. The patient was treated with prednisolone, sulphasalazine, metronidazole, azathioprine and tenofovir with good clinical response. As erythema elevatum diutinum can be secondary to multiple systemic diseases, including rheumatic diseases and inflammatory bowel disease, being aware and re - cognizing this entity can be of great importance for rheumatologists. |
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Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual associationCrohn's disea - seCutaneous vasculitisErythema elevatum diutinumSpondyloarthritisRheumatologySDG 3 - Good Health and Well-beingErythema elevatum diutinum is a rare neutrophilic dermatosis with vasculitis, which presents as persistent, symmetrical, purple or brownish papules and nodules, mainly in the extensor surface of the limbs. We describe a case of erythema elevatum diutinum and polyarthritis as initial manifestations of Crohn's disea se associated spondyloarthritis. A 51-year-old man, from São Tomé e Príncipe, with previous history of treated tuberculosis and chronic hepatitis B infection, was admitted due to 4 months history of polyarthritis, hyperpigmented papules on the extensor surfaces, occasional episodes of bloody mucous diarrhea and significant weight loss. Histology of the skin showed myeloperoxidase positive neutrophilic granulocytes with moderate karyorrhexis, consistent with erythema elevatum diutinum. Colonoscopy showed erosions in sigmoid and rectum. Diagnosis of erythema elevatum diutinum secondary to Crohn's disease with associated peripheral spondyloarthritis was assumed. The patient was treated with prednisolone, sulphasalazine, metronidazole, azathioprine and tenofovir with good clinical response. As erythema elevatum diutinum can be secondary to multiple systemic diseases, including rheumatic diseases and inflammatory bowel disease, being aware and re - cognizing this entity can be of great importance for rheumatologists.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Centro de Estudos de Doenças Crónicas (CEDOC)RUNGonçalves, Maria JoãoRomão, V. C.Soares-de-Almeida, L.Canhão, HelenaRomeu, J. C.Kutzner, H.Pereira-da-Silva, J. A.2018-02-05T23:16:00Z2017-102017-10-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article5application/pdfhttp://www.actareumatologica.pt/archive_detail.php?id=216eng0303-464XPURE: 3537937http://www.actareumatologica.pt/archive_detail.php?id=216info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:16:22Zoai:run.unl.pt:10362/29886Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:29:20.531333Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association |
title |
Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association |
spellingShingle |
Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association Gonçalves, Maria João Crohn's disea - se Cutaneous vasculitis Erythema elevatum diutinum Spondyloarthritis Rheumatology SDG 3 - Good Health and Well-being |
title_short |
Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association |
title_full |
Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association |
title_fullStr |
Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association |
title_full_unstemmed |
Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association |
title_sort |
Erythema elevatum diutinum in Crohn's disease-associated spondyloarthritis - A rare vasculitis, an unusual association |
author |
Gonçalves, Maria João |
author_facet |
Gonçalves, Maria João Romão, V. C. Soares-de-Almeida, L. Canhão, Helena Romeu, J. C. Kutzner, H. Pereira-da-Silva, J. A. |
author_role |
author |
author2 |
Romão, V. C. Soares-de-Almeida, L. Canhão, Helena Romeu, J. C. Kutzner, H. Pereira-da-Silva, J. A. |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) Centro de Estudos de Doenças Crónicas (CEDOC) RUN |
dc.contributor.author.fl_str_mv |
Gonçalves, Maria João Romão, V. C. Soares-de-Almeida, L. Canhão, Helena Romeu, J. C. Kutzner, H. Pereira-da-Silva, J. A. |
dc.subject.por.fl_str_mv |
Crohn's disea - se Cutaneous vasculitis Erythema elevatum diutinum Spondyloarthritis Rheumatology SDG 3 - Good Health and Well-being |
topic |
Crohn's disea - se Cutaneous vasculitis Erythema elevatum diutinum Spondyloarthritis Rheumatology SDG 3 - Good Health and Well-being |
description |
Erythema elevatum diutinum is a rare neutrophilic dermatosis with vasculitis, which presents as persistent, symmetrical, purple or brownish papules and nodules, mainly in the extensor surface of the limbs. We describe a case of erythema elevatum diutinum and polyarthritis as initial manifestations of Crohn's disea se associated spondyloarthritis. A 51-year-old man, from São Tomé e Príncipe, with previous history of treated tuberculosis and chronic hepatitis B infection, was admitted due to 4 months history of polyarthritis, hyperpigmented papules on the extensor surfaces, occasional episodes of bloody mucous diarrhea and significant weight loss. Histology of the skin showed myeloperoxidase positive neutrophilic granulocytes with moderate karyorrhexis, consistent with erythema elevatum diutinum. Colonoscopy showed erosions in sigmoid and rectum. Diagnosis of erythema elevatum diutinum secondary to Crohn's disease with associated peripheral spondyloarthritis was assumed. The patient was treated with prednisolone, sulphasalazine, metronidazole, azathioprine and tenofovir with good clinical response. As erythema elevatum diutinum can be secondary to multiple systemic diseases, including rheumatic diseases and inflammatory bowel disease, being aware and re - cognizing this entity can be of great importance for rheumatologists. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-10 2017-10-01T00:00:00Z 2018-02-05T23:16:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.actareumatologica.pt/archive_detail.php?id=216 |
url |
http://www.actareumatologica.pt/archive_detail.php?id=216 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0303-464X PURE: 3537937 http://www.actareumatologica.pt/archive_detail.php?id=216 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
5 application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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