A Multivariable Prediction Model to Select Colorectal Surgical Patients for Co-Management

Detalhes bibliográficos
Autor(a) principal: Horta, Alexandra Bayão
Data de Publicação: 2021
Outros Autores: Geraldes, Carlos, Salgado, Cátia, Vieira, Susana, Xavier, Miguel, Papoila, Ana Luísa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996
Resumo: Introduction: Increased life expectancy leads to older and frailer surgical patients. Co-management between medical and surgical specialities has proven favourable in complex situations. Selection of patients for co-management is full of difficulties. The aim of this study was to develop a clinical decision support tool to select surgical patients for co-management.Material and Methods: Clinical data was collected from patient electronic health records with an ICD-9 code for colorectal surgery from January 2012 to December 2015 at a hospital in Lisbon. The outcome variable consists in co-management signalling. A dataset from 344 patients was used to develop the prediction model and a second data set from 168 patients was used for external validation.Results: Using logistic regression modelling the authors built a five variable (age, burden of comorbidities, ASA-PS status, surgical risk and recovery time) predictive referral model for co-management. This model has an area under the curve (AUC) of 0.86 (95% CI: 0.81 - 0.90), a predictive Brier score of 0.11, a sensitivity of 0.80, a specificity of 0.82 and an accuracy of 81.3%.Discussion: Early referral of high-risk patients may be valuable to guide the decision on the best level of post-operative clinical care. We developed a simple bedside decision tool with a good discriminatory and predictive performance in order to select patients for comanagement.Conclusion: A simple bed-side clinical decision support tool of patients for co-management is viable, leading to potential improvement in early recognition and management of postoperative complications and reducing the ‘failure to rescue’. Generalizability to other clinical settings requires adequate customization and validation.
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spelling A Multivariable Prediction Model to Select Colorectal Surgical Patients for Co-ManagementUm Modelo de Predição para Seleccionar para Co-Gestão Doentes de Cirurgia Colo-rectalColorectal Surgery/methodsCooperative BehaviorDecision Support SystemsClinicalFailure to RescueHealth CarePatient SelectionCirurgia ColorrectalComportamento CooperativoFalha da Terapia de ResgateSelecção de DoentesSistemas de Apoio à Decisão ClínicaIntroduction: Increased life expectancy leads to older and frailer surgical patients. Co-management between medical and surgical specialities has proven favourable in complex situations. Selection of patients for co-management is full of difficulties. The aim of this study was to develop a clinical decision support tool to select surgical patients for co-management.Material and Methods: Clinical data was collected from patient electronic health records with an ICD-9 code for colorectal surgery from January 2012 to December 2015 at a hospital in Lisbon. The outcome variable consists in co-management signalling. A dataset from 344 patients was used to develop the prediction model and a second data set from 168 patients was used for external validation.Results: Using logistic regression modelling the authors built a five variable (age, burden of comorbidities, ASA-PS status, surgical risk and recovery time) predictive referral model for co-management. This model has an area under the curve (AUC) of 0.86 (95% CI: 0.81 - 0.90), a predictive Brier score of 0.11, a sensitivity of 0.80, a specificity of 0.82 and an accuracy of 81.3%.Discussion: Early referral of high-risk patients may be valuable to guide the decision on the best level of post-operative clinical care. We developed a simple bedside decision tool with a good discriminatory and predictive performance in order to select patients for comanagement.Conclusion: A simple bed-side clinical decision support tool of patients for co-management is viable, leading to potential improvement in early recognition and management of postoperative complications and reducing the ‘failure to rescue’. Generalizability to other clinical settings requires adequate customization and validation.Introdução: O aumento da esperança média de vida leva a que a população cirúrgica seja cada vez mais velha e frágil. Os modelos colaborativos de co-gestão entre especialidades médicas e cirúrgicas têm demonstrado ser favoráveis em situações complexas. A selecção de doentes para co-gestão está repleta de dificuldades. O objectivo deste estudo foi construir uma ferramenta de apoio à decisão para selecionar doentes de submetidos a cirurgia colo-rectal para co-gestão.Material e Métodos: A informação clínica foi colhida dos processos clínicos electrónicos de doentes que tiveram um código ICD-9 de cirurgia colo-rectal no período de janeiro 2012 a dezembro 2015, num hospital em Lisboa. A variável resposta consiste na sinalização para co-gestão. Um conjunto de dados de 344 doentes foi usado para o desenvolvimento do modelo predictivo e, um segundo conjunto de dados de 168 doentes foi usado para a validação externa do modelo.Resultados: Os autores construíram um modelo predictivo, de regressão logística, com cinco variáveis clínicas (idade, carga de co-morbilidades, ASA-PS status, risco cirúrgico e tempo de recobro) para predizer a selecção de doentes para co-gestão. O modelo tem uma área sob a curva (AUC) de 0,86 (95% IC: 0,81 - 0,90), um score predictivo de Brier de 0,11, uma sensibilidade de 0,80, uma especificidade de 0,82 e uma precisão de classificação de 81,3%.Discussão: A sinalização precoce dos doentes de alto risco ajuda a definir o melhor nível de cuidados ao doente operado. Desenvolvemos uma ferramenta de apoio à decisão, simples, aplicável à cabeceira do doente com uma boa capacidade discriminativa e preditiva para seleccionar os doentes para co-gestão.Conclusão: A selecção de doentes para co-gestão entre a cirurgia e a medicina interna permite o reconhecimento e a correcção precoce de complicações pós-operatórias reduzindo o ‘failure to rescue’. A ferramenta, uma vez customizada e validada, poderá ser aplicada em outros cenários clínicos.Ordem dos Médicos2021-02-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfimage/jpegimage/jpegimage/jpegapplication/pdfapplication/pdfapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/mswordapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996oai:ojs.www.actamedicaportuguesa.com:article/12996Acta Médica Portuguesa; Vol. 34 No. 2 (2021): February; 118-127Acta Médica Portuguesa; Vol. 34 N.º 2 (2021): Fevereiro; 118-1271646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/6188https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/11943https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/11944https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/11945https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/11981https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/11982https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/12204https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/12215https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/12470https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/12603Direitos de Autor (c) 2020 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessHorta, Alexandra BayãoGeraldes, CarlosSalgado, CátiaVieira, SusanaXavier, MiguelPapoila, Ana Luísa2022-12-20T11:06:45Zoai:ojs.www.actamedicaportuguesa.com:article/12996Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:20:15.752593Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A Multivariable Prediction Model to Select Colorectal Surgical Patients for Co-Management
Um Modelo de Predição para Seleccionar para Co-Gestão Doentes de Cirurgia Colo-rectal
title A Multivariable Prediction Model to Select Colorectal Surgical Patients for Co-Management
spellingShingle A Multivariable Prediction Model to Select Colorectal Surgical Patients for Co-Management
Horta, Alexandra Bayão
Colorectal Surgery/methods
Cooperative Behavior
Decision Support Systems
Clinical
Failure to Rescue
Health Care
Patient Selection
Cirurgia Colorrectal
Comportamento Cooperativo
Falha da Terapia de Resgate
Selecção de Doentes
Sistemas de Apoio à Decisão Clínica
title_short A Multivariable Prediction Model to Select Colorectal Surgical Patients for Co-Management
title_full A Multivariable Prediction Model to Select Colorectal Surgical Patients for Co-Management
title_fullStr A Multivariable Prediction Model to Select Colorectal Surgical Patients for Co-Management
title_full_unstemmed A Multivariable Prediction Model to Select Colorectal Surgical Patients for Co-Management
title_sort A Multivariable Prediction Model to Select Colorectal Surgical Patients for Co-Management
author Horta, Alexandra Bayão
author_facet Horta, Alexandra Bayão
Geraldes, Carlos
Salgado, Cátia
Vieira, Susana
Xavier, Miguel
Papoila, Ana Luísa
author_role author
author2 Geraldes, Carlos
Salgado, Cátia
Vieira, Susana
Xavier, Miguel
Papoila, Ana Luísa
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Horta, Alexandra Bayão
Geraldes, Carlos
Salgado, Cátia
Vieira, Susana
Xavier, Miguel
Papoila, Ana Luísa
dc.subject.por.fl_str_mv Colorectal Surgery/methods
Cooperative Behavior
Decision Support Systems
Clinical
Failure to Rescue
Health Care
Patient Selection
Cirurgia Colorrectal
Comportamento Cooperativo
Falha da Terapia de Resgate
Selecção de Doentes
Sistemas de Apoio à Decisão Clínica
topic Colorectal Surgery/methods
Cooperative Behavior
Decision Support Systems
Clinical
Failure to Rescue
Health Care
Patient Selection
Cirurgia Colorrectal
Comportamento Cooperativo
Falha da Terapia de Resgate
Selecção de Doentes
Sistemas de Apoio à Decisão Clínica
description Introduction: Increased life expectancy leads to older and frailer surgical patients. Co-management between medical and surgical specialities has proven favourable in complex situations. Selection of patients for co-management is full of difficulties. The aim of this study was to develop a clinical decision support tool to select surgical patients for co-management.Material and Methods: Clinical data was collected from patient electronic health records with an ICD-9 code for colorectal surgery from January 2012 to December 2015 at a hospital in Lisbon. The outcome variable consists in co-management signalling. A dataset from 344 patients was used to develop the prediction model and a second data set from 168 patients was used for external validation.Results: Using logistic regression modelling the authors built a five variable (age, burden of comorbidities, ASA-PS status, surgical risk and recovery time) predictive referral model for co-management. This model has an area under the curve (AUC) of 0.86 (95% CI: 0.81 - 0.90), a predictive Brier score of 0.11, a sensitivity of 0.80, a specificity of 0.82 and an accuracy of 81.3%.Discussion: Early referral of high-risk patients may be valuable to guide the decision on the best level of post-operative clinical care. We developed a simple bedside decision tool with a good discriminatory and predictive performance in order to select patients for comanagement.Conclusion: A simple bed-side clinical decision support tool of patients for co-management is viable, leading to potential improvement in early recognition and management of postoperative complications and reducing the ‘failure to rescue’. Generalizability to other clinical settings requires adequate customization and validation.
publishDate 2021
dc.date.none.fl_str_mv 2021-02-01
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url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996
identifier_str_mv oai:ojs.www.actamedicaportuguesa.com:article/12996
dc.language.iso.fl_str_mv eng
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dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/6188
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/11943
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/11944
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/11945
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/11981
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/11982
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/12204
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/12215
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/12470
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/12996/12603
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2020 Acta Médica Portuguesa
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Direitos de Autor (c) 2020 Acta Médica Portuguesa
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 34 No. 2 (2021): February; 118-127
Acta Médica Portuguesa; Vol. 34 N.º 2 (2021): Fevereiro; 118-127
1646-0758
0870-399X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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