Accuracy of prenatal culture in predicting intrapartum group B streptococcus colonization status

• Autor(a) principal: Florindo, C
• Data de Publicação: 2014
• Outros Autores: Damião, V, Lima, J, Nogueira, I, Rocha, I, Caetano, P, Ribeiro, L, Viegas, S, Gomes, JP, Borrego, MJ
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://hdl.handle.net/10400.26/6472
• topic: Pregnancy Complications, Infectious; Streptococcal Infections; Infectious Disease Transmission, Vertical; Infecções por Estafilocócos; Complicações Infecciosas na Gravidez; Transmissão Vertical de Doença Infecciosa

OBJECTIVE: To evaluate the positive predictive value (PPV) of group B Streptococcus (GBS) cultures at 35-37 weeks of gestation relative to GBS colonization status at delivery. METHODS: Rectovaginal swabs from 221 women at labor in four Lisbon hospitals were collected for GBS screening according to the CDC guidelines. RESULTS: The PPV was 24.4%. IAP was administered to 100% of prenatally GBS positive women. There was no case of early onset GBS disease (EOD). CONCLUSIONS: Poor accuracy of prenatal cultures in identifying true candidates for IAP highlights the need for Portuguese clinical and laboratory guidelines to prevent EOD and antibiotic overtreatment of pregnant women.