Simulating substrate binding sites in the S. aureus Type II NADH Dehydrogenase

Detalhes bibliográficos
Autor(a) principal: Barriga, Rodrigo
Data de Publicação: 2023
Outros Autores: Orientador: Melo, Manuel
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/151163
Resumo: "Type II NADH Oxidoreductase (NDH-2) from Staphylococcus aureus was established as a therapeutic target against the virulency of this bacterium and an alternative to treat Complex I-derived diseases. To accurately model interactions of NDH-2 with its substrates such as menaquinones and NADH, Coarse-Grain (CG) simulations were employed. "
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spelling Simulating substrate binding sites in the S. aureus Type II NADH DehydrogenaseCoarse-GrainMartini 3"Type II NADH Oxidoreductase (NDH-2) from Staphylococcus aureus was established as a therapeutic target against the virulency of this bacterium and an alternative to treat Complex I-derived diseases. To accurately model interactions of NDH-2 with its substrates such as menaquinones and NADH, Coarse-Grain (CG) simulations were employed. "Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica António XavierRUNBarriga, RodrigoOrientador: Melo, Manuel2023-03-24T19:29:44Z2023-02-102023-02-10T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10362/151163enginfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:33:38Zoai:run.unl.pt:10362/151163Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:54:29.732927Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Simulating substrate binding sites in the S. aureus Type II NADH Dehydrogenase
title Simulating substrate binding sites in the S. aureus Type II NADH Dehydrogenase
spellingShingle Simulating substrate binding sites in the S. aureus Type II NADH Dehydrogenase
Barriga, Rodrigo
Coarse-Grain
Martini 3
title_short Simulating substrate binding sites in the S. aureus Type II NADH Dehydrogenase
title_full Simulating substrate binding sites in the S. aureus Type II NADH Dehydrogenase
title_fullStr Simulating substrate binding sites in the S. aureus Type II NADH Dehydrogenase
title_full_unstemmed Simulating substrate binding sites in the S. aureus Type II NADH Dehydrogenase
title_sort Simulating substrate binding sites in the S. aureus Type II NADH Dehydrogenase
author Barriga, Rodrigo
author_facet Barriga, Rodrigo
Orientador: Melo, Manuel
author_role author
author2 Orientador: Melo, Manuel
author2_role author
dc.contributor.none.fl_str_mv RUN
dc.contributor.author.fl_str_mv Barriga, Rodrigo
Orientador: Melo, Manuel
dc.subject.por.fl_str_mv Coarse-Grain
Martini 3
topic Coarse-Grain
Martini 3
description "Type II NADH Oxidoreductase (NDH-2) from Staphylococcus aureus was established as a therapeutic target against the virulency of this bacterium and an alternative to treat Complex I-derived diseases. To accurately model interactions of NDH-2 with its substrates such as menaquinones and NADH, Coarse-Grain (CG) simulations were employed. "
publishDate 2023
dc.date.none.fl_str_mv 2023-03-24T19:29:44Z
2023-02-10
2023-02-10T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/151163
url http://hdl.handle.net/10362/151163
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica António Xavier
publisher.none.fl_str_mv Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica António Xavier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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