Hyperparathyroidism, Serum Phosphorus and Dietary Intake in Hemodialysis Patients

Detalhes bibliográficos
Autor(a) principal: Garagarza, Cristina
Data de Publicação: 2024
Outros Autores: Valente, Ana, Queirós, Cátia, Neto, Inês Pastor, Sebastião, Joana, Gomes, Melanie, Ferreira, Aníbal
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/164572
Resumo: Publisher Copyright: © 2024 by the authors.
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spelling Hyperparathyroidism, Serum Phosphorus and Dietary Intake in Hemodialysis PatientsIs There a Novel Relationship?dialysisfood intakenutritional statusparathyroid hormoneCatalysisMolecular BiologySpectroscopyComputer Science ApplicationsPhysical and Theoretical ChemistryOrganic ChemistryInorganic ChemistryPublisher Copyright: © 2024 by the authors.The management of hyperparathyroidism (intact parathyroid hormone (iPTH) serum levels > 585 pg/mL), frequently focuses on the appropriate control of mineral and bone markers, with the decrease in serum and dietary phosphorus as two of the targets. We aimed to investigate the association between iPTH, serum phosphorus levels and dietary intake. This was a cross-sectional, multicenter, observational study with 561 patients on hemodialysis treatment. Clinical parameters, body composition and dietary intake were assessed. For the analysis, patients were divided into three groups: (a) iPTH < 130, (b) iPTH between 130 and 585 and (c) iPTH > 585 pg/mL. The association between PTH, serum phosphorus and dietary intake was analyzed using linear regression models. In the whole sample, 23.2% of patients presented an iPTH > 585 pg/mL. Patients with higher iPTH levels were those with longer HD vintage and lower ages, higher serum phosphorus, serum calcium, Ca/P product, albumin and caffeine intake, and a lower dietary intake of phosphorus, fiber, riboflavin and folate. Higher serum phosphorus predicted higher iPTH levels, even in the adjusted model. However, lower dietary phosphorus and fiber intake were predictors of higher iPTH levels, including in the adjusted model. Our results bring new data to the relationship between dietary intake and iPTH values. Despite higher serum phosphorus being observed in patients with HPTH, an opposite association was noted regarding dietary phosphate and fiber.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNGaragarza, CristinaValente, AnaQueirós, CátiaNeto, Inês PastorSebastião, JoanaGomes, MelanieFerreira, Aníbal2024-03-06T23:52:51Z2024-022024-02-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/164572eng1661-6596PURE: 84546488https://doi.org/10.3390/ijms25042006info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-18T01:44:14Zoai:run.unl.pt:10362/164572Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T04:00:15.674254Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Hyperparathyroidism, Serum Phosphorus and Dietary Intake in Hemodialysis Patients
Is There a Novel Relationship?
title Hyperparathyroidism, Serum Phosphorus and Dietary Intake in Hemodialysis Patients
spellingShingle Hyperparathyroidism, Serum Phosphorus and Dietary Intake in Hemodialysis Patients
Garagarza, Cristina
dialysis
food intake
nutritional status
parathyroid hormone
Catalysis
Molecular Biology
Spectroscopy
Computer Science Applications
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry
title_short Hyperparathyroidism, Serum Phosphorus and Dietary Intake in Hemodialysis Patients
title_full Hyperparathyroidism, Serum Phosphorus and Dietary Intake in Hemodialysis Patients
title_fullStr Hyperparathyroidism, Serum Phosphorus and Dietary Intake in Hemodialysis Patients
title_full_unstemmed Hyperparathyroidism, Serum Phosphorus and Dietary Intake in Hemodialysis Patients
title_sort Hyperparathyroidism, Serum Phosphorus and Dietary Intake in Hemodialysis Patients
author Garagarza, Cristina
author_facet Garagarza, Cristina
Valente, Ana
Queirós, Cátia
Neto, Inês Pastor
Sebastião, Joana
Gomes, Melanie
Ferreira, Aníbal
author_role author
author2 Valente, Ana
Queirós, Cátia
Neto, Inês Pastor
Sebastião, Joana
Gomes, Melanie
Ferreira, Aníbal
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
RUN
dc.contributor.author.fl_str_mv Garagarza, Cristina
Valente, Ana
Queirós, Cátia
Neto, Inês Pastor
Sebastião, Joana
Gomes, Melanie
Ferreira, Aníbal
dc.subject.por.fl_str_mv dialysis
food intake
nutritional status
parathyroid hormone
Catalysis
Molecular Biology
Spectroscopy
Computer Science Applications
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry
topic dialysis
food intake
nutritional status
parathyroid hormone
Catalysis
Molecular Biology
Spectroscopy
Computer Science Applications
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry
description Publisher Copyright: © 2024 by the authors.
publishDate 2024
dc.date.none.fl_str_mv 2024-03-06T23:52:51Z
2024-02
2024-02-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/164572
url http://hdl.handle.net/10362/164572
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1661-6596
PURE: 84546488
https://doi.org/10.3390/ijms25042006
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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