Self-reported testing, HIV status and associated risk behaviours among people who inject drugs in Europe: important differences between East and West

Detalhes bibliográficos
Autor(a) principal: Uuskula, A
Data de Publicação: 2014
Outros Autores: Raag, M, Folch, C, Prasad, L, Karnite, A, van Veen, MG
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10216/114883
Resumo: Aims: To describe HIV-related risk behaviours, HIV testing and HIV status among people who inject drugs (PWIDs) in the 2000 in European countries with high-prevalence HIV epidemics among PWID. Methods: Data from 12 cross-sectional studies among PWID from seven countries were used. Meta-analysis was used to synthesize the data and meta-regression to explain heterogeneity [in addition to deriving adjusted odds ratios (AORmeta)]. Results: Data on 1791 PWID from western (the West) and 3537 from central and eastern (the East) European countries were available. The mean age of participating PWIDs was 30.6 years (SD 7.9), 75% were men, and 36% [95% confidence interval 34–37%) were HIV-infected (30% West, 38% East); 22% had not previously been tested for HIV. The prevalence of reported high-risk behaviour was significantly higher among PWID from the East. Comparison of HIV-infected and uninfected PWID within countries yielded similar results across all countries: HIV-infected PWID were less likely to be sexually active [AORmeta 0.69 (0.58–0.81)], reported less unprotected sex [AORmeta 0.59 (0.40–0.83)], but reported more syringe sharing [AORmeta 1.70 (1.30–2.00)] and more frequent injecting [AORmeta 1.40 (1.20–1.70)] than their HIV-uninfected counterparts. Conclusion: Despite the absolute differences in reported risk behaviours among PWID in western and eastern Europe, the associations of risk behaviours with HIV status were similar across the sites and regions. There is a substantial potential for further HIV transmission and acquisition based on the continuous risk behaviours reported. HIV prevention and harm reduction interventions targeting PWID should be evaluated.
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spelling Self-reported testing, HIV status and associated risk behaviours among people who inject drugs in Europe: important differences between East and WestHIV/AIDSRisk behavioursAims: To describe HIV-related risk behaviours, HIV testing and HIV status among people who inject drugs (PWIDs) in the 2000 in European countries with high-prevalence HIV epidemics among PWID. Methods: Data from 12 cross-sectional studies among PWID from seven countries were used. Meta-analysis was used to synthesize the data and meta-regression to explain heterogeneity [in addition to deriving adjusted odds ratios (AORmeta)]. Results: Data on 1791 PWID from western (the West) and 3537 from central and eastern (the East) European countries were available. The mean age of participating PWIDs was 30.6 years (SD 7.9), 75% were men, and 36% [95% confidence interval 34–37%) were HIV-infected (30% West, 38% East); 22% had not previously been tested for HIV. The prevalence of reported high-risk behaviour was significantly higher among PWID from the East. Comparison of HIV-infected and uninfected PWID within countries yielded similar results across all countries: HIV-infected PWID were less likely to be sexually active [AORmeta 0.69 (0.58–0.81)], reported less unprotected sex [AORmeta 0.59 (0.40–0.83)], but reported more syringe sharing [AORmeta 1.70 (1.30–2.00)] and more frequent injecting [AORmeta 1.40 (1.20–1.70)] than their HIV-uninfected counterparts. Conclusion: Despite the absolute differences in reported risk behaviours among PWID in western and eastern Europe, the associations of risk behaviours with HIV status were similar across the sites and regions. There is a substantial potential for further HIV transmission and acquisition based on the continuous risk behaviours reported. HIV prevention and harm reduction interventions targeting PWID should be evaluated.20142014-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10216/114883eng0269-9370 10.1097/QAD.0000000000000299Uuskula, ARaag, MFolch, CPrasad, LKarnite, Avan Veen, MGinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T13:40:45Zoai:repositorio-aberto.up.pt:10216/114883Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:45:30.153644Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Self-reported testing, HIV status and associated risk behaviours among people who inject drugs in Europe: important differences between East and West
title Self-reported testing, HIV status and associated risk behaviours among people who inject drugs in Europe: important differences between East and West
spellingShingle Self-reported testing, HIV status and associated risk behaviours among people who inject drugs in Europe: important differences between East and West
Uuskula, A
HIV/AIDS
Risk behaviours
title_short Self-reported testing, HIV status and associated risk behaviours among people who inject drugs in Europe: important differences between East and West
title_full Self-reported testing, HIV status and associated risk behaviours among people who inject drugs in Europe: important differences between East and West
title_fullStr Self-reported testing, HIV status and associated risk behaviours among people who inject drugs in Europe: important differences between East and West
title_full_unstemmed Self-reported testing, HIV status and associated risk behaviours among people who inject drugs in Europe: important differences between East and West
title_sort Self-reported testing, HIV status and associated risk behaviours among people who inject drugs in Europe: important differences between East and West
author Uuskula, A
author_facet Uuskula, A
Raag, M
Folch, C
Prasad, L
Karnite, A
van Veen, MG
author_role author
author2 Raag, M
Folch, C
Prasad, L
Karnite, A
van Veen, MG
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Uuskula, A
Raag, M
Folch, C
Prasad, L
Karnite, A
van Veen, MG
dc.subject.por.fl_str_mv HIV/AIDS
Risk behaviours
topic HIV/AIDS
Risk behaviours
description Aims: To describe HIV-related risk behaviours, HIV testing and HIV status among people who inject drugs (PWIDs) in the 2000 in European countries with high-prevalence HIV epidemics among PWID. Methods: Data from 12 cross-sectional studies among PWID from seven countries were used. Meta-analysis was used to synthesize the data and meta-regression to explain heterogeneity [in addition to deriving adjusted odds ratios (AORmeta)]. Results: Data on 1791 PWID from western (the West) and 3537 from central and eastern (the East) European countries were available. The mean age of participating PWIDs was 30.6 years (SD 7.9), 75% were men, and 36% [95% confidence interval 34–37%) were HIV-infected (30% West, 38% East); 22% had not previously been tested for HIV. The prevalence of reported high-risk behaviour was significantly higher among PWID from the East. Comparison of HIV-infected and uninfected PWID within countries yielded similar results across all countries: HIV-infected PWID were less likely to be sexually active [AORmeta 0.69 (0.58–0.81)], reported less unprotected sex [AORmeta 0.59 (0.40–0.83)], but reported more syringe sharing [AORmeta 1.70 (1.30–2.00)] and more frequent injecting [AORmeta 1.40 (1.20–1.70)] than their HIV-uninfected counterparts. Conclusion: Despite the absolute differences in reported risk behaviours among PWID in western and eastern Europe, the associations of risk behaviours with HIV status were similar across the sites and regions. There is a substantial potential for further HIV transmission and acquisition based on the continuous risk behaviours reported. HIV prevention and harm reduction interventions targeting PWID should be evaluated.
publishDate 2014
dc.date.none.fl_str_mv 2014
2014-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10216/114883
url http://hdl.handle.net/10216/114883
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0269-9370 
10.1097/QAD.0000000000000299
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dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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