Genome analysis of Legionella pneumophila ST23 from various countries reveals highly similar strains
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10451/51991 |
Resumo: | © 2022 Ricci et al. This article is available under a CreativeCommons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/). |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Genome analysis of Legionella pneumophila ST23 from various countries reveals highly similar strains© 2022 Ricci et al. This article is available under a CreativeCommons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/).Legionella pneumophila serogroup 1 (Lp1) sequence type (ST) 23 is one of the most commonly detected STs in Italy where it currently causes all investigated outbreaks. ST23 has caused both epidemic and sporadic cases between 1995 and 2018 and was analysed at genomic level and compared with ST23 isolated in other countries to determine possible similarities and differences. A core genome multi-locus sequence typing (cgMLST), based on a previously described set of 1,521 core genes, and single-nucleotide polymorphisms (SNPs) approaches were applied to an ST23 collection including genomes from Italy, France, Denmark and Scotland. DNAs were automatically extracted, libraries prepared using NextEra library kit and MiSeq sequencing performed. Overall, 63 among clinical and environmental Italian Lp1 isolates and a further seven and 11 ST23 from Denmark and Scotland, respectively, were sequenced, and pangenome analysed. Both cgMLST and SNPs analyses showed very few loci and SNP variations in ST23 genomes. All the ST23 causing outbreaks and sporadic cases in Italy and elsewhere, were phylogenetically related independent of year, town or country of isolation. Distances among the ST23s were further shortened when SNPs due to horizontal gene transfers were removed. The Lp1 ST23 isolated in Italy have kept their monophyletic origin, but they are phylogenetically close also to ST23 from other countries. The ST23 are quite widespread in Italy, and a thorough epidemiological investigation is compelled to determine sources of infection when this ST is identified in both LD sporadic cases and outbreaks.Life Science Alliance LLC.Repositório da Universidade de LisboaRicci, Maria LuisaFillo, SilviaCiammaruconi, AndreaLista, FlorigioGinevra, ChristopheJarraud, SophieGirolamo, AntoniettaBarbanti, FabrizioRota, Maria CristinaLindsay, DianeGorzynski, JamieUldum, Søren ABaig, SharminFoti, MarinaPetralito, GiancarloTorri, StefaniaFaccini, MarinoBonini, MairaGentili, GabriellaSenatore, SabrinaLamberti, AnnaCarrico, Joao AndreScaturro, Maria2022-03-25T16:41:34Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/51991engLife Sci Alliance. 2022 Mar 2;5(6):e20210111710.26508/lsa.2021011172575-1077info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:57:01Zoai:repositorio.ul.pt:10451/51991Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:03:10.505302Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Genome analysis of Legionella pneumophila ST23 from various countries reveals highly similar strains |
| title |
Genome analysis of Legionella pneumophila ST23 from various countries reveals highly similar strains |
| spellingShingle |
Genome analysis of Legionella pneumophila ST23 from various countries reveals highly similar strains Ricci, Maria Luisa |
| title_short |
Genome analysis of Legionella pneumophila ST23 from various countries reveals highly similar strains |
| title_full |
Genome analysis of Legionella pneumophila ST23 from various countries reveals highly similar strains |
| title_fullStr |
Genome analysis of Legionella pneumophila ST23 from various countries reveals highly similar strains |
| title_full_unstemmed |
Genome analysis of Legionella pneumophila ST23 from various countries reveals highly similar strains |
| title_sort |
Genome analysis of Legionella pneumophila ST23 from various countries reveals highly similar strains |
| author |
Ricci, Maria Luisa |
| author_facet |
Ricci, Maria Luisa Fillo, Silvia Ciammaruconi, Andrea Lista, Florigio Ginevra, Christophe Jarraud, Sophie Girolamo, Antonietta Barbanti, Fabrizio Rota, Maria Cristina Lindsay, Diane Gorzynski, Jamie Uldum, Søren A Baig, Sharmin Foti, Marina Petralito, Giancarlo Torri, Stefania Faccini, Marino Bonini, Maira Gentili, Gabriella Senatore, Sabrina Lamberti, Anna Carrico, Joao Andre Scaturro, Maria |
| author_role |
author |
| author2 |
Fillo, Silvia Ciammaruconi, Andrea Lista, Florigio Ginevra, Christophe Jarraud, Sophie Girolamo, Antonietta Barbanti, Fabrizio Rota, Maria Cristina Lindsay, Diane Gorzynski, Jamie Uldum, Søren A Baig, Sharmin Foti, Marina Petralito, Giancarlo Torri, Stefania Faccini, Marino Bonini, Maira Gentili, Gabriella Senatore, Sabrina Lamberti, Anna Carrico, Joao Andre Scaturro, Maria |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
| dc.contributor.author.fl_str_mv |
Ricci, Maria Luisa Fillo, Silvia Ciammaruconi, Andrea Lista, Florigio Ginevra, Christophe Jarraud, Sophie Girolamo, Antonietta Barbanti, Fabrizio Rota, Maria Cristina Lindsay, Diane Gorzynski, Jamie Uldum, Søren A Baig, Sharmin Foti, Marina Petralito, Giancarlo Torri, Stefania Faccini, Marino Bonini, Maira Gentili, Gabriella Senatore, Sabrina Lamberti, Anna Carrico, Joao Andre Scaturro, Maria |
| description |
© 2022 Ricci et al. This article is available under a CreativeCommons License (Attribution 4.0 International, as described at https://creativecommons.org/licenses/by/4.0/). |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-03-25T16:41:34Z 2022 2022-01-01T00:00:00Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10451/51991 |
| url |
http://hdl.handle.net/10451/51991 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Life Sci Alliance. 2022 Mar 2;5(6):e202101117 10.26508/lsa.202101117 2575-1077 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
Life Science Alliance LLC. |
| publisher.none.fl_str_mv |
Life Science Alliance LLC. |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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