Potential health risk of endocrine disruptors in construction sector and plastics industry
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.3390/ijerph15061229 |
Resumo: | Endocrine disruptors (EDs) belong to large and diverse groups of agents that may cause multiple biological effects associated with, for example, hormone imbalance and infertility, chronic diseases such as diabetes, genome damage and cancer. The health risks related with the exposure to EDs are typically underestimated, less well characterized, and not regulated to the same extent as, for example, carcinogens. The increased production and utilization of identified or suspected EDs in many different technological processes raises new challenges with respect to occupational exposure settings and associated health risks. Due to the specific profile of health risk, occupational exposure to EDs demands a new paradigm in health risk assessment, redefinition of exposure assessment, new effects biomarkers for occupational health surveillance and definition of limit values. The construction and plastics industries are among the strongest economic sectors, employing millions of workers globally. They also use large quantities of chemicals that are known or suspected EDs. Focusing on these two industries, this short communication discusses: (a) why occupational exposure to EDs needs a more specific approach to occupational health risk assessments, (b) identifies the current knowledge gaps, and (c) identifies and gives a rationale for a future occupational health paradigm, which will include ED biomarkers as a relevant parameter in occupational health risk assessment, surveillance and exposure prevention. |
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Potential health risk of endocrine disruptors in construction sector and plastics industryA new paradigm in occupational healthBiomarkersConstruction sectorEndocrine disruptionFertilityPlastics industryPublic Health, Environmental and Occupational HealthHealth, Toxicology and MutagenesisSDG 3 - Good Health and Well-beingEndocrine disruptors (EDs) belong to large and diverse groups of agents that may cause multiple biological effects associated with, for example, hormone imbalance and infertility, chronic diseases such as diabetes, genome damage and cancer. The health risks related with the exposure to EDs are typically underestimated, less well characterized, and not regulated to the same extent as, for example, carcinogens. The increased production and utilization of identified or suspected EDs in many different technological processes raises new challenges with respect to occupational exposure settings and associated health risks. Due to the specific profile of health risk, occupational exposure to EDs demands a new paradigm in health risk assessment, redefinition of exposure assessment, new effects biomarkers for occupational health surveillance and definition of limit values. The construction and plastics industries are among the strongest economic sectors, employing millions of workers globally. They also use large quantities of chemicals that are known or suspected EDs. Focusing on these two industries, this short communication discusses: (a) why occupational exposure to EDs needs a more specific approach to occupational health risk assessments, (b) identifies the current knowledge gaps, and (c) identifies and gives a rationale for a future occupational health paradigm, which will include ED biomarkers as a relevant parameter in occupational health risk assessment, surveillance and exposure prevention.Centro de Investigação em Saúde Pública (CISP/PHRC)RUNFucic, AleksandraGalea, Karen S.Duca, Radu CorneliuEl Yamani, MouniaFrery, NadineGodderis, LodeHalldorsson, Thórhallur IngiIavicoli, IvoNdaw, SophieRibeiro, EdnaViegas, SusanaMoshammer, Hanns2018-07-27T22:13:06Z2018-06-112018-06-11T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.3390/ijerph15061229eng1661-7827PURE: 5616239http://www.scopus.com/inward/record.url?scp=85048640839&partnerID=8YFLogxKhttps://doi.org/10.3390/ijerph15061229info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:23:00Zoai:run.unl.pt:10362/42671Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:31:31.375759Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Potential health risk of endocrine disruptors in construction sector and plastics industry A new paradigm in occupational health |
title |
Potential health risk of endocrine disruptors in construction sector and plastics industry |
spellingShingle |
Potential health risk of endocrine disruptors in construction sector and plastics industry Fucic, Aleksandra Biomarkers Construction sector Endocrine disruption Fertility Plastics industry Public Health, Environmental and Occupational Health Health, Toxicology and Mutagenesis SDG 3 - Good Health and Well-being |
title_short |
Potential health risk of endocrine disruptors in construction sector and plastics industry |
title_full |
Potential health risk of endocrine disruptors in construction sector and plastics industry |
title_fullStr |
Potential health risk of endocrine disruptors in construction sector and plastics industry |
title_full_unstemmed |
Potential health risk of endocrine disruptors in construction sector and plastics industry |
title_sort |
Potential health risk of endocrine disruptors in construction sector and plastics industry |
author |
Fucic, Aleksandra |
author_facet |
Fucic, Aleksandra Galea, Karen S. Duca, Radu Corneliu El Yamani, Mounia Frery, Nadine Godderis, Lode Halldorsson, Thórhallur Ingi Iavicoli, Ivo Ndaw, Sophie Ribeiro, Edna Viegas, Susana Moshammer, Hanns |
author_role |
author |
author2 |
Galea, Karen S. Duca, Radu Corneliu El Yamani, Mounia Frery, Nadine Godderis, Lode Halldorsson, Thórhallur Ingi Iavicoli, Ivo Ndaw, Sophie Ribeiro, Edna Viegas, Susana Moshammer, Hanns |
author2_role |
author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Centro de Investigação em Saúde Pública (CISP/PHRC) RUN |
dc.contributor.author.fl_str_mv |
Fucic, Aleksandra Galea, Karen S. Duca, Radu Corneliu El Yamani, Mounia Frery, Nadine Godderis, Lode Halldorsson, Thórhallur Ingi Iavicoli, Ivo Ndaw, Sophie Ribeiro, Edna Viegas, Susana Moshammer, Hanns |
dc.subject.por.fl_str_mv |
Biomarkers Construction sector Endocrine disruption Fertility Plastics industry Public Health, Environmental and Occupational Health Health, Toxicology and Mutagenesis SDG 3 - Good Health and Well-being |
topic |
Biomarkers Construction sector Endocrine disruption Fertility Plastics industry Public Health, Environmental and Occupational Health Health, Toxicology and Mutagenesis SDG 3 - Good Health and Well-being |
description |
Endocrine disruptors (EDs) belong to large and diverse groups of agents that may cause multiple biological effects associated with, for example, hormone imbalance and infertility, chronic diseases such as diabetes, genome damage and cancer. The health risks related with the exposure to EDs are typically underestimated, less well characterized, and not regulated to the same extent as, for example, carcinogens. The increased production and utilization of identified or suspected EDs in many different technological processes raises new challenges with respect to occupational exposure settings and associated health risks. Due to the specific profile of health risk, occupational exposure to EDs demands a new paradigm in health risk assessment, redefinition of exposure assessment, new effects biomarkers for occupational health surveillance and definition of limit values. The construction and plastics industries are among the strongest economic sectors, employing millions of workers globally. They also use large quantities of chemicals that are known or suspected EDs. Focusing on these two industries, this short communication discusses: (a) why occupational exposure to EDs needs a more specific approach to occupational health risk assessments, (b) identifies the current knowledge gaps, and (c) identifies and gives a rationale for a future occupational health paradigm, which will include ED biomarkers as a relevant parameter in occupational health risk assessment, surveillance and exposure prevention. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-07-27T22:13:06Z 2018-06-11 2018-06-11T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.3390/ijerph15061229 |
url |
https://doi.org/10.3390/ijerph15061229 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1661-7827 PURE: 5616239 http://www.scopus.com/inward/record.url?scp=85048640839&partnerID=8YFLogxK https://doi.org/10.3390/ijerph15061229 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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