On similarities in infrared spectra of complex drugs

Detalhes bibliográficos
Autor(a) principal: Machado, J. A. Tenreiro
Data de Publicação: 2014
Outros Autores: Baleanu, Dumitru, Al-Zhrani, Abdulrahim A., Alhamed, Yahia A., Zahid, Adnan H., Youssef, Tamer E.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.22/5472
Resumo: A chromatographic separation of active ingredients of Combivir, Epivir, Kaletra, Norvir, Prezista, Retrovir, Trivizir, Valcyte, and Viramune is performed on thin layer chromatography. The spectra of these nine drugs were recorded using the Fourier transform infrared spectroscopy. This information is then analyzed by means of the cosine correlation. The comparison of the infrared spectra in the perspective of the adopted similarity measure is possible to visualize with present day computer tools, and the emerging clusters provide additional information about the similarities of the investigated set of complex drugs.
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spelling On similarities in infrared spectra of complex drugsChromatographic separationCombivirEpivirKaletraNorvirPrezistaRetrovirTrivizirValcyteViramuneVisualizationA chromatographic separation of active ingredients of Combivir, Epivir, Kaletra, Norvir, Prezista, Retrovir, Trivizir, Valcyte, and Viramune is performed on thin layer chromatography. The spectra of these nine drugs were recorded using the Fourier transform infrared spectroscopy. This information is then analyzed by means of the cosine correlation. The comparison of the infrared spectra in the perspective of the adopted similarity measure is possible to visualize with present day computer tools, and the emerging clusters provide additional information about the similarities of the investigated set of complex drugs.Editura Academiei RomaneRepositório Científico do Instituto Politécnico do PortoMachado, J. A. TenreiroBaleanu, DumitruAl-Zhrani, Abdulrahim A.Alhamed, Yahia A.Zahid, Adnan H.Youssef, Tamer E.2015-01-22T16:17:51Z20142014-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/5472eng1221-1451metadata only accessinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-13T12:45:34Zoai:recipp.ipp.pt:10400.22/5472Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:26:08.275428Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv On similarities in infrared spectra of complex drugs
title On similarities in infrared spectra of complex drugs
spellingShingle On similarities in infrared spectra of complex drugs
Machado, J. A. Tenreiro
Chromatographic separation
Combivir
Epivir
Kaletra
Norvir
Prezista
Retrovir
Trivizir
Valcyte
Viramune
Visualization
title_short On similarities in infrared spectra of complex drugs
title_full On similarities in infrared spectra of complex drugs
title_fullStr On similarities in infrared spectra of complex drugs
title_full_unstemmed On similarities in infrared spectra of complex drugs
title_sort On similarities in infrared spectra of complex drugs
author Machado, J. A. Tenreiro
author_facet Machado, J. A. Tenreiro
Baleanu, Dumitru
Al-Zhrani, Abdulrahim A.
Alhamed, Yahia A.
Zahid, Adnan H.
Youssef, Tamer E.
author_role author
author2 Baleanu, Dumitru
Al-Zhrani, Abdulrahim A.
Alhamed, Yahia A.
Zahid, Adnan H.
Youssef, Tamer E.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Politécnico do Porto
dc.contributor.author.fl_str_mv Machado, J. A. Tenreiro
Baleanu, Dumitru
Al-Zhrani, Abdulrahim A.
Alhamed, Yahia A.
Zahid, Adnan H.
Youssef, Tamer E.
dc.subject.por.fl_str_mv Chromatographic separation
Combivir
Epivir
Kaletra
Norvir
Prezista
Retrovir
Trivizir
Valcyte
Viramune
Visualization
topic Chromatographic separation
Combivir
Epivir
Kaletra
Norvir
Prezista
Retrovir
Trivizir
Valcyte
Viramune
Visualization
description A chromatographic separation of active ingredients of Combivir, Epivir, Kaletra, Norvir, Prezista, Retrovir, Trivizir, Valcyte, and Viramune is performed on thin layer chromatography. The spectra of these nine drugs were recorded using the Fourier transform infrared spectroscopy. This information is then analyzed by means of the cosine correlation. The comparison of the infrared spectra in the perspective of the adopted similarity measure is possible to visualize with present day computer tools, and the emerging clusters provide additional information about the similarities of the investigated set of complex drugs.
publishDate 2014
dc.date.none.fl_str_mv 2014
2014-01-01T00:00:00Z
2015-01-22T16:17:51Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/5472
url http://hdl.handle.net/10400.22/5472
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1221-1451
dc.rights.driver.fl_str_mv metadata only access
info:eu-repo/semantics/openAccess
rights_invalid_str_mv metadata only access
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Editura Academiei Romane
publisher.none.fl_str_mv Editura Academiei Romane
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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