PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY

Detalhes bibliográficos
Autor(a) principal: Andrade, Pedro
Data de Publicação: 2011
Outros Autores: Brites, Maria Manuel, Alexandrino, Henrique, Figueiredo, Américo
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.29021/spdv.69.3.84
Resumo: We present the case of a 67-year-old patient observed with multiple painful violaceous plaques with central pustules on distal lower limbs, rapidly transforming into deep ulcers with infiltrated undermined borders and centrifuge progression, associated with mucous bloody diarrhea, oral erosions and hyperthermia in the previous three months. Histopathologic skin examination was consistent with the diagnosis of pyoderma gangrenosum (PG). Subtotal colonoscopy showed a severe continuous rectocolitis, consistent with unspecific inflammatory bowel disease (IBD). Due to colonic perforation, the patient was submitted to left colectomy, and afterwards to total proctocolectomy. Treatment with topical corticosteroids was performed and complete ulcer healing was observed three months after surgery, without recurrence in the following 2 years. Pustular PG is a rare condition; the relevance of this case is supported not only by the synergic evolution of severe pustular PG and IBD, but also by the prompt regression of the former after proctoco- lectomy.KEYWORDS – Pyoderma Gangrenosum; Inflammatory Bowel Diseases; Proctocolectomy.
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spelling PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMYPIODERMA GANGRENOSO PUSTULOSO E DOENÇA INFLAMATÓRIA INTESTINAL – RESOLUÇÃO APÓS PROCTOCOLECTOMIAWe present the case of a 67-year-old patient observed with multiple painful violaceous plaques with central pustules on distal lower limbs, rapidly transforming into deep ulcers with infiltrated undermined borders and centrifuge progression, associated with mucous bloody diarrhea, oral erosions and hyperthermia in the previous three months. Histopathologic skin examination was consistent with the diagnosis of pyoderma gangrenosum (PG). Subtotal colonoscopy showed a severe continuous rectocolitis, consistent with unspecific inflammatory bowel disease (IBD). Due to colonic perforation, the patient was submitted to left colectomy, and afterwards to total proctocolectomy. Treatment with topical corticosteroids was performed and complete ulcer healing was observed three months after surgery, without recurrence in the following 2 years. Pustular PG is a rare condition; the relevance of this case is supported not only by the synergic evolution of severe pustular PG and IBD, but also by the prompt regression of the former after proctoco- lectomy.KEYWORDS – Pyoderma Gangrenosum; Inflammatory Bowel Diseases; Proctocolectomy.Relata-se o caso de doente de 67 anos de idade observada com placas eritematovioláceas dolorosas centradas por pústulas nas extremidades dos membros inferiores, com evolução de 1 mês, progredindo para lesões ulceradas de crescimento centrífugo, com bordos infiltrados e descolados, com análise histológica compatível com pioderma gangrenoso. Associava diarreia mucopiossanguinolenta, erosões orais e febre, com 3 meses de evolu- ção. A colonoscopia subtotal foi sugestiva de doença inflamatória intestinal com envolvimento contínuo da mucosa visualizada. Ao 10o dia de internamento foi submetida a colectomia esquerda na sequência de perfuração cólica, e posteriormente a proctocolectomia total por complicação pós-operatória. Observou-se cicatrização rápida das lesões nos 3 meses seguintes, sob tratamento com dermocorticóide, sem recidiva em follow-up de 2 anos. O pioderma gangrenoso pustuloso é uma entidade clínica rara; salienta-se neste caso a evolução sinérgica das do- enças intestinal e cutânea, e em particular a rápida resolução do quadro cutâneo após proctocolectomia.PALAVRAS-CHAVE – Pioderma Gangrenoso; Doença Inflamatória Intestinal; Proctocolectomia.Sociedade Portuguesa de Dermatologia e Venereologia2011-09-28T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.69.3.84oai:ojs.revista.spdv.com.pt:article/84Journal of the Portuguese Society of Dermatology and Venereology; Vol 69 No 3 (2011): Julho - Setembro; 461Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 69 n. 3 (2011): Julho - Setembro; 4612182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/84https://doi.org/10.29021/spdv.69.3.84https://revista.spdv.com.pt/index.php/spdv/article/view/84/82Andrade, PedroBrites, Maria ManuelAlexandrino, HenriqueFigueiredo, Américoinfo:eu-repo/semantics/openAccess2022-10-06T12:34:40Zoai:ojs.revista.spdv.com.pt:article/84Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:10:40.744458Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY
PIODERMA GANGRENOSO PUSTULOSO E DOENÇA INFLAMATÓRIA INTESTINAL – RESOLUÇÃO APÓS PROCTOCOLECTOMIA
title PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY
spellingShingle PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY
Andrade, Pedro
title_short PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY
title_full PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY
title_fullStr PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY
title_full_unstemmed PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY
title_sort PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY
author Andrade, Pedro
author_facet Andrade, Pedro
Brites, Maria Manuel
Alexandrino, Henrique
Figueiredo, Américo
author_role author
author2 Brites, Maria Manuel
Alexandrino, Henrique
Figueiredo, Américo
author2_role author
author
author
dc.contributor.author.fl_str_mv Andrade, Pedro
Brites, Maria Manuel
Alexandrino, Henrique
Figueiredo, Américo
description We present the case of a 67-year-old patient observed with multiple painful violaceous plaques with central pustules on distal lower limbs, rapidly transforming into deep ulcers with infiltrated undermined borders and centrifuge progression, associated with mucous bloody diarrhea, oral erosions and hyperthermia in the previous three months. Histopathologic skin examination was consistent with the diagnosis of pyoderma gangrenosum (PG). Subtotal colonoscopy showed a severe continuous rectocolitis, consistent with unspecific inflammatory bowel disease (IBD). Due to colonic perforation, the patient was submitted to left colectomy, and afterwards to total proctocolectomy. Treatment with topical corticosteroids was performed and complete ulcer healing was observed three months after surgery, without recurrence in the following 2 years. Pustular PG is a rare condition; the relevance of this case is supported not only by the synergic evolution of severe pustular PG and IBD, but also by the prompt regression of the former after proctoco- lectomy.KEYWORDS – Pyoderma Gangrenosum; Inflammatory Bowel Diseases; Proctocolectomy.
publishDate 2011
dc.date.none.fl_str_mv 2011-09-28T00:00:00Z
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dc.identifier.uri.fl_str_mv https://doi.org/10.29021/spdv.69.3.84
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dc.relation.none.fl_str_mv https://revista.spdv.com.pt/index.php/spdv/article/view/84
https://doi.org/10.29021/spdv.69.3.84
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dc.publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
dc.source.none.fl_str_mv Journal of the Portuguese Society of Dermatology and Venereology; Vol 69 No 3 (2011): Julho - Setembro; 461
Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 69 n. 3 (2011): Julho - Setembro; 461
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