PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.29021/spdv.69.3.84 |
Resumo: | We present the case of a 67-year-old patient observed with multiple painful violaceous plaques with central pustules on distal lower limbs, rapidly transforming into deep ulcers with infiltrated undermined borders and centrifuge progression, associated with mucous bloody diarrhea, oral erosions and hyperthermia in the previous three months. Histopathologic skin examination was consistent with the diagnosis of pyoderma gangrenosum (PG). Subtotal colonoscopy showed a severe continuous rectocolitis, consistent with unspecific inflammatory bowel disease (IBD). Due to colonic perforation, the patient was submitted to left colectomy, and afterwards to total proctocolectomy. Treatment with topical corticosteroids was performed and complete ulcer healing was observed three months after surgery, without recurrence in the following 2 years. Pustular PG is a rare condition; the relevance of this case is supported not only by the synergic evolution of severe pustular PG and IBD, but also by the prompt regression of the former after proctoco- lectomy.KEYWORDS – Pyoderma Gangrenosum; Inflammatory Bowel Diseases; Proctocolectomy. |
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PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMYPIODERMA GANGRENOSO PUSTULOSO E DOENÇA INFLAMATÓRIA INTESTINAL – RESOLUÇÃO APÓS PROCTOCOLECTOMIAWe present the case of a 67-year-old patient observed with multiple painful violaceous plaques with central pustules on distal lower limbs, rapidly transforming into deep ulcers with infiltrated undermined borders and centrifuge progression, associated with mucous bloody diarrhea, oral erosions and hyperthermia in the previous three months. Histopathologic skin examination was consistent with the diagnosis of pyoderma gangrenosum (PG). Subtotal colonoscopy showed a severe continuous rectocolitis, consistent with unspecific inflammatory bowel disease (IBD). Due to colonic perforation, the patient was submitted to left colectomy, and afterwards to total proctocolectomy. Treatment with topical corticosteroids was performed and complete ulcer healing was observed three months after surgery, without recurrence in the following 2 years. Pustular PG is a rare condition; the relevance of this case is supported not only by the synergic evolution of severe pustular PG and IBD, but also by the prompt regression of the former after proctoco- lectomy.KEYWORDS – Pyoderma Gangrenosum; Inflammatory Bowel Diseases; Proctocolectomy.Relata-se o caso de doente de 67 anos de idade observada com placas eritematovioláceas dolorosas centradas por pústulas nas extremidades dos membros inferiores, com evolução de 1 mês, progredindo para lesões ulceradas de crescimento centrífugo, com bordos infiltrados e descolados, com análise histológica compatível com pioderma gangrenoso. Associava diarreia mucopiossanguinolenta, erosões orais e febre, com 3 meses de evolu- ção. A colonoscopia subtotal foi sugestiva de doença inflamatória intestinal com envolvimento contínuo da mucosa visualizada. Ao 10o dia de internamento foi submetida a colectomia esquerda na sequência de perfuração cólica, e posteriormente a proctocolectomia total por complicação pós-operatória. Observou-se cicatrização rápida das lesões nos 3 meses seguintes, sob tratamento com dermocorticóide, sem recidiva em follow-up de 2 anos. O pioderma gangrenoso pustuloso é uma entidade clínica rara; salienta-se neste caso a evolução sinérgica das do- enças intestinal e cutânea, e em particular a rápida resolução do quadro cutâneo após proctocolectomia.PALAVRAS-CHAVE – Pioderma Gangrenoso; Doença Inflamatória Intestinal; Proctocolectomia.Sociedade Portuguesa de Dermatologia e Venereologia2011-09-28T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.69.3.84oai:ojs.revista.spdv.com.pt:article/84Journal of the Portuguese Society of Dermatology and Venereology; Vol 69 No 3 (2011): Julho - Setembro; 461Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 69 n. 3 (2011): Julho - Setembro; 4612182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/84https://doi.org/10.29021/spdv.69.3.84https://revista.spdv.com.pt/index.php/spdv/article/view/84/82Andrade, PedroBrites, Maria ManuelAlexandrino, HenriqueFigueiredo, Américoinfo:eu-repo/semantics/openAccess2022-10-06T12:34:40Zoai:ojs.revista.spdv.com.pt:article/84Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:10:40.744458Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY PIODERMA GANGRENOSO PUSTULOSO E DOENÇA INFLAMATÓRIA INTESTINAL – RESOLUÇÃO APÓS PROCTOCOLECTOMIA |
title |
PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY |
spellingShingle |
PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY Andrade, Pedro |
title_short |
PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY |
title_full |
PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY |
title_fullStr |
PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY |
title_full_unstemmed |
PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY |
title_sort |
PUSTULAR PYODERMA GANGRENOSUM AND INFLAMMATORY BOWEL DISEASE – HEALING AFTER PROCTOCOLECTOMY |
author |
Andrade, Pedro |
author_facet |
Andrade, Pedro Brites, Maria Manuel Alexandrino, Henrique Figueiredo, Américo |
author_role |
author |
author2 |
Brites, Maria Manuel Alexandrino, Henrique Figueiredo, Américo |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Andrade, Pedro Brites, Maria Manuel Alexandrino, Henrique Figueiredo, Américo |
description |
We present the case of a 67-year-old patient observed with multiple painful violaceous plaques with central pustules on distal lower limbs, rapidly transforming into deep ulcers with infiltrated undermined borders and centrifuge progression, associated with mucous bloody diarrhea, oral erosions and hyperthermia in the previous three months. Histopathologic skin examination was consistent with the diagnosis of pyoderma gangrenosum (PG). Subtotal colonoscopy showed a severe continuous rectocolitis, consistent with unspecific inflammatory bowel disease (IBD). Due to colonic perforation, the patient was submitted to left colectomy, and afterwards to total proctocolectomy. Treatment with topical corticosteroids was performed and complete ulcer healing was observed three months after surgery, without recurrence in the following 2 years. Pustular PG is a rare condition; the relevance of this case is supported not only by the synergic evolution of severe pustular PG and IBD, but also by the prompt regression of the former after proctoco- lectomy.KEYWORDS – Pyoderma Gangrenosum; Inflammatory Bowel Diseases; Proctocolectomy. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-09-28T00:00:00Z |
dc.type.driver.fl_str_mv |
journal article info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.29021/spdv.69.3.84 oai:ojs.revista.spdv.com.pt:article/84 |
url |
https://doi.org/10.29021/spdv.69.3.84 |
identifier_str_mv |
oai:ojs.revista.spdv.com.pt:article/84 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revista.spdv.com.pt/index.php/spdv/article/view/84 https://doi.org/10.29021/spdv.69.3.84 https://revista.spdv.com.pt/index.php/spdv/article/view/84/82 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
dc.source.none.fl_str_mv |
Journal of the Portuguese Society of Dermatology and Venereology; Vol 69 No 3 (2011): Julho - Setembro; 461 Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 69 n. 3 (2011): Julho - Setembro; 461 2182-2409 2182-2395 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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