Reporting SOFA in research
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2023 |
| Outros Autores: | , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10362/162976 |
Resumo: | Publisher Copyright: © 2023 Via Medica. All rights reserved. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Reporting SOFA in researchwe should always present each of the SOFA subscoresmultiorgan dysfunctionorgan failureSequential Organ Failure AssessmentSOFA scoreCritical Care and Intensive Care MedicineAnesthesiology and Pain MedicinePublisher Copyright: © 2023 Via Medica. All rights reserved.Background: The Sequential Organ Failure Assessment (SOFA) score is the sum of 6 components, each representing one organ system with dysfunction classified on a 4-point scale. In research, usually by default, the total SOFA score is taken into account, but it may not reflect the severity of the condition of the individual organs. Often, these values are expected to predict mortality. Methods: In this study, we reanalysed 2 cohorts of critically ill elderly patients to explore the distribution of SOFA subscores and to assess the between-group differences. Both cohorts were adjusted to maintain similarity in terms of age and the primary cause of admission (respiratory cause). Results: In total, 910 (non-COVID-19 cohort) and 551 patients (COVID-19 cohort) were included in the analysis. Both cohorts were similar in terms of the total SOFA score (median 5 vs. 5 points); however, the groups differed significantly in 4/6 SOFA subscores (respiratory, neurological, cardiovascular, and coagulation subscores). Moreover, the cohorts had different fractions of organ failures (defined as a SOFA subscore ≥ 3). Conclusions: This analysis revealed significant differences in SOFA subscores between the COVID-19 and non-COVID-19 respiratory cohorts, highlighting the importance of considering individual organ dysfunction rather than relying solely on the total SOFA score when reporting organ dysfunction in clinical research.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNPutowski, ZbigniewCzok, MarcelinaPolok, KamilGuidet, BertrandJung, ChristianBruno, Raphael Romanode Lange, DylanLeaver, SusannahMoreno, RuiWernly, BernhardFlaatten, HansSzczeklik, Wojciech2024-01-31T23:35:54Z2023-122023-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article4application/pdfhttp://hdl.handle.net/10362/162976eng1642-5758PURE: 82401829https://doi.org/10.5114/ait.2023.134188info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:46:01Zoai:run.unl.pt:10362/162976Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:59:12.774063Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Reporting SOFA in research we should always present each of the SOFA subscores |
| title |
Reporting SOFA in research |
| spellingShingle |
Reporting SOFA in research Putowski, Zbigniew multiorgan dysfunction organ failure Sequential Organ Failure Assessment SOFA score Critical Care and Intensive Care Medicine Anesthesiology and Pain Medicine |
| title_short |
Reporting SOFA in research |
| title_full |
Reporting SOFA in research |
| title_fullStr |
Reporting SOFA in research |
| title_full_unstemmed |
Reporting SOFA in research |
| title_sort |
Reporting SOFA in research |
| author |
Putowski, Zbigniew |
| author_facet |
Putowski, Zbigniew Czok, Marcelina Polok, Kamil Guidet, Bertrand Jung, Christian Bruno, Raphael Romano de Lange, Dylan Leaver, Susannah Moreno, Rui Wernly, Bernhard Flaatten, Hans Szczeklik, Wojciech |
| author_role |
author |
| author2 |
Czok, Marcelina Polok, Kamil Guidet, Bertrand Jung, Christian Bruno, Raphael Romano de Lange, Dylan Leaver, Susannah Moreno, Rui Wernly, Bernhard Flaatten, Hans Szczeklik, Wojciech |
| author2_role |
author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) RUN |
| dc.contributor.author.fl_str_mv |
Putowski, Zbigniew Czok, Marcelina Polok, Kamil Guidet, Bertrand Jung, Christian Bruno, Raphael Romano de Lange, Dylan Leaver, Susannah Moreno, Rui Wernly, Bernhard Flaatten, Hans Szczeklik, Wojciech |
| dc.subject.por.fl_str_mv |
multiorgan dysfunction organ failure Sequential Organ Failure Assessment SOFA score Critical Care and Intensive Care Medicine Anesthesiology and Pain Medicine |
| topic |
multiorgan dysfunction organ failure Sequential Organ Failure Assessment SOFA score Critical Care and Intensive Care Medicine Anesthesiology and Pain Medicine |
| description |
Publisher Copyright: © 2023 Via Medica. All rights reserved. |
| publishDate |
2023 |
| dc.date.none.fl_str_mv |
2023-12 2023-12-01T00:00:00Z 2024-01-31T23:35:54Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
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publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/162976 |
| url |
http://hdl.handle.net/10362/162976 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
1642-5758 PURE: 82401829 https://doi.org/10.5114/ait.2023.134188 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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4 application/pdf |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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