Antimicrobial effect of chitosan against periodontal pathogens biofilms
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.14/34725 |
Resumo: | Over the years authors have established that chitosan possesses significant antimicrobial activity against planktonic bacteria however, little is known about the effect of chitosan upon sessile microbial communities. The aim of this work was to assess the effect of chitosan against 5 periodontal pathogens, Porphyromonasgingivalis, Prevotellaintermedia, Prevotellabuccae, Tanerellaforsythensis and Aggregatibacter actinomycetemcomitans biofilm formation. The results obtained show that both high molecular weight and low molecular weight chitosan were capable of inhibiting biofilm formation and biofilm associated phenomena. Sub-MIC concentrations of chitosan inhibited single species biofilm formation up to 90% and dual species biofilms formation up to 80%. Furthermore analysis of the effect of chitosan upon quorum sensing showed inhibition values that reached 70% after 24h exposure to chitosan. The results obtained open new possibilities in the fight against biofilm formation in the oral cavity and the prevention of undesirable microbiological colonization following dental treatments. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Antimicrobial effect of chitosan against periodontal pathogens biofilmsBiofilmChitosanDual speciesSub-MICQuorum SensingOver the years authors have established that chitosan possesses significant antimicrobial activity against planktonic bacteria however, little is known about the effect of chitosan upon sessile microbial communities. The aim of this work was to assess the effect of chitosan against 5 periodontal pathogens, Porphyromonasgingivalis, Prevotellaintermedia, Prevotellabuccae, Tanerellaforsythensis and Aggregatibacter actinomycetemcomitans biofilm formation. The results obtained show that both high molecular weight and low molecular weight chitosan were capable of inhibiting biofilm formation and biofilm associated phenomena. Sub-MIC concentrations of chitosan inhibited single species biofilm formation up to 90% and dual species biofilms formation up to 80%. Furthermore analysis of the effect of chitosan upon quorum sensing showed inhibition values that reached 70% after 24h exposure to chitosan. The results obtained open new possibilities in the fight against biofilm formation in the oral cavity and the prevention of undesirable microbiological colonization following dental treatments.Veritati - Repositório Institucional da Universidade Católica PortuguesaCosta, Eduardo M.Silva, SaraPina, CristinaTavaria, Freni K.Pintado, Manuela2021-09-10T10:15:41Z2014-01-012014-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.14/34725eng2372-095610.15226/sojmid.2013.00114info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-12T17:40:13Zoai:repositorio.ucp.pt:10400.14/34725Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:28:09.036237Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Antimicrobial effect of chitosan against periodontal pathogens biofilms |
title |
Antimicrobial effect of chitosan against periodontal pathogens biofilms |
spellingShingle |
Antimicrobial effect of chitosan against periodontal pathogens biofilms Costa, Eduardo M. Biofilm Chitosan Dual species Sub-MIC Quorum Sensing |
title_short |
Antimicrobial effect of chitosan against periodontal pathogens biofilms |
title_full |
Antimicrobial effect of chitosan against periodontal pathogens biofilms |
title_fullStr |
Antimicrobial effect of chitosan against periodontal pathogens biofilms |
title_full_unstemmed |
Antimicrobial effect of chitosan against periodontal pathogens biofilms |
title_sort |
Antimicrobial effect of chitosan against periodontal pathogens biofilms |
author |
Costa, Eduardo M. |
author_facet |
Costa, Eduardo M. Silva, Sara Pina, Cristina Tavaria, Freni K. Pintado, Manuela |
author_role |
author |
author2 |
Silva, Sara Pina, Cristina Tavaria, Freni K. Pintado, Manuela |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Veritati - Repositório Institucional da Universidade Católica Portuguesa |
dc.contributor.author.fl_str_mv |
Costa, Eduardo M. Silva, Sara Pina, Cristina Tavaria, Freni K. Pintado, Manuela |
dc.subject.por.fl_str_mv |
Biofilm Chitosan Dual species Sub-MIC Quorum Sensing |
topic |
Biofilm Chitosan Dual species Sub-MIC Quorum Sensing |
description |
Over the years authors have established that chitosan possesses significant antimicrobial activity against planktonic bacteria however, little is known about the effect of chitosan upon sessile microbial communities. The aim of this work was to assess the effect of chitosan against 5 periodontal pathogens, Porphyromonasgingivalis, Prevotellaintermedia, Prevotellabuccae, Tanerellaforsythensis and Aggregatibacter actinomycetemcomitans biofilm formation. The results obtained show that both high molecular weight and low molecular weight chitosan were capable of inhibiting biofilm formation and biofilm associated phenomena. Sub-MIC concentrations of chitosan inhibited single species biofilm formation up to 90% and dual species biofilms formation up to 80%. Furthermore analysis of the effect of chitosan upon quorum sensing showed inhibition values that reached 70% after 24h exposure to chitosan. The results obtained open new possibilities in the fight against biofilm formation in the oral cavity and the prevention of undesirable microbiological colonization following dental treatments. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-01-01 2014-01-01T00:00:00Z 2021-09-10T10:15:41Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.14/34725 |
url |
http://hdl.handle.net/10400.14/34725 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2372-0956 10.15226/sojmid.2013.00114 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799131999580979200 |