Endoscopic Ultrasound-Guided Celiac Plexus Interventions

• Autor(a) principal: Moutinho-Ribeiro, Pedro
• Data de Publicação: 2021
• Outros Autores: Costa-Moreira, Pedro, Caldeira, Ana, Leite, Sílvia, Marques, Susana, Moreira, Teresa, Nunes, Nuno, Bispo, Miguel
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://hdl.handle.net/10400.16/2638
• topic: Celiac plexus block; Celiac plexus interventions; Celiac plexus neurolysis; Chronic pain; Chronic pancreatitis; Pancreatic cancer

Abdominal pain related to pancreatic disease is often extremely disabling. Endoscopic ultrasound (EUS)-guided celiac plexus block (CPB) is used to control pain associated with chronic pancreatitis. EUS-guided celiac plexus neurolysis (CPN) is typically used to reduce pain associated with pancreatic cancer and can be considered early at the time of diagnosis of inoperable disease. EUS-guided celiac plexus interventions have been shown to be significantly effective in pancreatic pain relief, which is achieved in approximately 70-80% of patients with pancreatic cancer and in 50-60% of those with chronic pancreatitis. Serious complications from CPB and CPN are rare. Most frequent adverse events are diarrhoea, orthostatic hypotension, and a transient increase in abdominal pain. In this article, the Portuguese Group for Ultrasound in Gastroenterology (GRUPUGE) presents an updated perspective of the potential role of EUS-guided celiac plexus interventions, addressing the selection criteria and technical issues of different techniques and analysing recent data on their safety and efficacy.