Persistent short nighttime sleep duration is associated with a greater post-COVID risk in fully mRNA-vaccinated individuals
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10451/56245 |
Resumo: | © The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
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Persistent short nighttime sleep duration is associated with a greater post-COVID risk in fully mRNA-vaccinated individuals© The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.Short nighttime sleep duration impairs the immune response to virus vaccination, and long nighttime sleep duration is associated with poor health status. Thus, we hypothesized that short (<6 h) and long (>9 h) nighttime sleepers have a higher post-COVID risk than normal nighttime sleepers, despite two doses of mRNA vaccine (which has previously been linked to lower odds of long-lasting COVID-19 symptoms). Post-COVID was defined as experiencing at least one core COVID-19 symptom for at least three months (e.g., shortness of breath). Multivariate logistic regression adjusting for age, sex, BMI, and other factors showed in 9717 respondents (age span 18-99) that two mRNA vaccinations lowered the risk of suffering from post-COVID by about 21% (p < 0.001). When restricting the analysis to double-vaccinated respondents (n = 5918), short and long sleepers exhibited a greater post-COVID risk than normal sleepers (adjusted OR [95%-CI], 1.56 [1.29, 1.88] and 1.87 [1.32, 2.66], respectively). Among respondents with persistent sleep duration patterns during the pandemic compared to before the pandemic, short but not long sleep duration was significantly associated with the post-COVID risk (adjusted OR [95%-CI], 1.59 [1.24, 2.03] and 1.18 [0.70, 1.97], respectively). No significant association between sleep duration and post-COVID symptoms was observed in those reporting positive SARS-CoV-2 test results (n = 538). Our findings suggest that two mRNA vaccinations against SARS-CoV-2 are associated with a lower post-COVID risk. However, this protection may be less pronounced among those sleeping less than 6 h per night. Our findings warrant replication in cohorts with individuals with confirmed SARS-CoV-2 infection.CB’s research is financially supported by the Swedish Brain Research Foundation [FO2022-0254]. PX’s research is financially supported by the Åke Wiberg Foundation [M22-0081]. MP’s research is is financially supported by Signe and Arne Gyllenberg Foundation.Springer NatureRepositório da Universidade de LisboaXue, PeiMerikanto, IlonaChung, FrancesMorin, Charles M.Espie, ColinBjorvatn, BjørnCedernaes, JonathanLandtblom, Anne-MariePenzel, ThomasDe Gennaro, LuigiHolzinger, BrigitteMatsui, KentaroHrubos-Strøm, HaraldKorman, MariaLeger, DamienMota-Rolim, SérgioBolstad, Courtney J.Nadorff, MichaelPlazzi, GiuseppeReis, CátiaChan, Rachel Ngan YinWing, Yun KwokYordanova, JulianaBjelajac, Adrijana KoscecInoue, YuichiPartinen, MarkkuDauvilliers, YvesBenedict, Christian2023-02-10T12:12:37Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/56245engTransl Psychiatry. 2023 Feb 1;13(1):3210.1038/s41398-023-02334-42158-3188info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T17:03:42Zoai:repositorio.ul.pt:10451/56245Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:06:48.016247Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Persistent short nighttime sleep duration is associated with a greater post-COVID risk in fully mRNA-vaccinated individuals |
title |
Persistent short nighttime sleep duration is associated with a greater post-COVID risk in fully mRNA-vaccinated individuals |
spellingShingle |
Persistent short nighttime sleep duration is associated with a greater post-COVID risk in fully mRNA-vaccinated individuals Xue, Pei |
title_short |
Persistent short nighttime sleep duration is associated with a greater post-COVID risk in fully mRNA-vaccinated individuals |
title_full |
Persistent short nighttime sleep duration is associated with a greater post-COVID risk in fully mRNA-vaccinated individuals |
title_fullStr |
Persistent short nighttime sleep duration is associated with a greater post-COVID risk in fully mRNA-vaccinated individuals |
title_full_unstemmed |
Persistent short nighttime sleep duration is associated with a greater post-COVID risk in fully mRNA-vaccinated individuals |
title_sort |
Persistent short nighttime sleep duration is associated with a greater post-COVID risk in fully mRNA-vaccinated individuals |
author |
Xue, Pei |
author_facet |
Xue, Pei Merikanto, Ilona Chung, Frances Morin, Charles M. Espie, Colin Bjorvatn, Bjørn Cedernaes, Jonathan Landtblom, Anne-Marie Penzel, Thomas De Gennaro, Luigi Holzinger, Brigitte Matsui, Kentaro Hrubos-Strøm, Harald Korman, Maria Leger, Damien Mota-Rolim, Sérgio Bolstad, Courtney J. Nadorff, Michael Plazzi, Giuseppe Reis, Cátia Chan, Rachel Ngan Yin Wing, Yun Kwok Yordanova, Juliana Bjelajac, Adrijana Koscec Inoue, Yuichi Partinen, Markku Dauvilliers, Yves Benedict, Christian |
author_role |
author |
author2 |
Merikanto, Ilona Chung, Frances Morin, Charles M. Espie, Colin Bjorvatn, Bjørn Cedernaes, Jonathan Landtblom, Anne-Marie Penzel, Thomas De Gennaro, Luigi Holzinger, Brigitte Matsui, Kentaro Hrubos-Strøm, Harald Korman, Maria Leger, Damien Mota-Rolim, Sérgio Bolstad, Courtney J. Nadorff, Michael Plazzi, Giuseppe Reis, Cátia Chan, Rachel Ngan Yin Wing, Yun Kwok Yordanova, Juliana Bjelajac, Adrijana Koscec Inoue, Yuichi Partinen, Markku Dauvilliers, Yves Benedict, Christian |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
dc.contributor.author.fl_str_mv |
Xue, Pei Merikanto, Ilona Chung, Frances Morin, Charles M. Espie, Colin Bjorvatn, Bjørn Cedernaes, Jonathan Landtblom, Anne-Marie Penzel, Thomas De Gennaro, Luigi Holzinger, Brigitte Matsui, Kentaro Hrubos-Strøm, Harald Korman, Maria Leger, Damien Mota-Rolim, Sérgio Bolstad, Courtney J. Nadorff, Michael Plazzi, Giuseppe Reis, Cátia Chan, Rachel Ngan Yin Wing, Yun Kwok Yordanova, Juliana Bjelajac, Adrijana Koscec Inoue, Yuichi Partinen, Markku Dauvilliers, Yves Benedict, Christian |
description |
© The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-02-10T12:12:37Z 2023 2023-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10451/56245 |
url |
http://hdl.handle.net/10451/56245 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Transl Psychiatry. 2023 Feb 1;13(1):32 10.1038/s41398-023-02334-4 2158-3188 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Springer Nature |
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Springer Nature |
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