Undifferentiated thyroid carcinoma – An unusual case

• Autor(a) principal: Serralheiro, Pedro Miguel Azevedo
• Data de Publicação: 2012
• Outros Autores: Dionísio, Isabel Margarida Cardoso, Ferreira, Miguel Semião Vaz, Moreira, Maria Augusta da Costa, Silveira, Luís Filipe da Fonseca Lopes
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://revista.spcir.com/index.php/spcir/article/view/59

Introduction: The undifferentiated carcinoma accounts about 1.6 to 14% of all thyroid malignancies. It is an extremely aggressive cancer with poor prognosis, with metastasis at diagnosis in 20-75% of the patients and a median survival of four to 12 months. Case: Women of 83 years, seen in consult by left cervical adenopathic mass. It was performed puncture biopsy, which revealed a papillary thyroid carcinoma. Posteriorly in the biopsy site, appeared a vegetative lesion, leading to a total thyroidectomy with cervical lymphadenectomy, which was radical at the left and modified at the right, excision of the vegetative lesion and reconstruction of the residual lesion with a delto-pectoral flap. The histology showed an undifferentiated thyroid carcinoma. Thirteen months after, arose an ulcerated right axillary nodule. We carried out excision with radical axillary lymphadenectomy, showing a metastatic carcinoma of the thyroid. After five months, appeared a right submammary cutaneous nodule, which was excised, revealing a new metastasis. In a setback of 47 months the patient remained free from detectable disease. Discussion: We present this case because of the unique biological evolution of this tumor and the long survival presented by the patient, unusual in these cases. Keywords: Anaplastic Carcinoma; Undifferentiated Carcinoma; Thyroid Neoplasms.