Sickle cell disease and cerebrovascular stroke: a preventable event.

Detalhes bibliográficos
Autor(a) principal: Simões, Ana Sofia
Data de Publicação: 2011
Outros Autores: Garcia, Pedro, Fernandes, Isabel, Ventura, Lurdes, Silva, Rita, Barata, Deolinda
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/475
Resumo: About 75% of the children presenting with cerebrovascular stroke have an identified cause. For black children, the most common underlying condition is sickle cell disease. This case report describes a preventable natural history, with an unusual presenting feature.27th month black infant without relevant background, presented with an acute focal neurological deficit. Brain computed tomography scan showed extensive acute infarction, and magnetic resonance also revealed previous silent cerebral infarct. Blood sample showed normocytic anemia and spontaneous sickling of the red blood cells, with 87% hemoglobin S. Exchange transfusion was made.Stroke, as a sickle cell disease complication, can occur at early ages and being the presenting sign. We consider that it would be worth spread the antenatal hemoglobinopathy screening programme, and evaluating the cost-effectiveness of a neonatal screening programme for sickle cell disease in Portugal.
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spelling Sickle cell disease and cerebrovascular stroke: a preventable event.Anemia de células falciformes e acidente vascular cerebral: uma história evitável.About 75% of the children presenting with cerebrovascular stroke have an identified cause. For black children, the most common underlying condition is sickle cell disease. This case report describes a preventable natural history, with an unusual presenting feature.27th month black infant without relevant background, presented with an acute focal neurological deficit. Brain computed tomography scan showed extensive acute infarction, and magnetic resonance also revealed previous silent cerebral infarct. Blood sample showed normocytic anemia and spontaneous sickling of the red blood cells, with 87% hemoglobin S. Exchange transfusion was made.Stroke, as a sickle cell disease complication, can occur at early ages and being the presenting sign. We consider that it would be worth spread the antenatal hemoglobinopathy screening programme, and evaluating the cost-effectiveness of a neonatal screening programme for sickle cell disease in Portugal.About 75% of the children presenting with cerebrovascular stroke have an identified cause. For black children, the most common underlying condition is sickle cell disease. This case report describes a preventable natural history, with an unusual presenting feature.27th month black infant without relevant background, presented with an acute focal neurological deficit. Brain computed tomography scan showed extensive acute infarction, and magnetic resonance also revealed previous silent cerebral infarct. Blood sample showed normocytic anemia and spontaneous sickling of the red blood cells, with 87% hemoglobin S. Exchange transfusion was made.Stroke, as a sickle cell disease complication, can occur at early ages and being the presenting sign. We consider that it would be worth spread the antenatal hemoglobinopathy screening programme, and evaluating the cost-effectiveness of a neonatal screening programme for sickle cell disease in Portugal.Ordem dos Médicos2011-12-12info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/475oai:ojs.www.actamedicaportuguesa.com:article/475Acta Médica Portuguesa; Vol. 24 No. 4 (2011): Julho-Agosto; 637-40Acta Médica Portuguesa; Vol. 24 N.º 4 (2011): Julho-Agosto; 637-401646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/475https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/475/183Simões, Ana SofiaGarcia, PedroFernandes, IsabelVentura, LurdesSilva, RitaBarata, Deolindainfo:eu-repo/semantics/openAccess2022-12-20T10:56:18Zoai:ojs.www.actamedicaportuguesa.com:article/475Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:16:31.094180Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Sickle cell disease and cerebrovascular stroke: a preventable event.
Anemia de células falciformes e acidente vascular cerebral: uma história evitável.
title Sickle cell disease and cerebrovascular stroke: a preventable event.
spellingShingle Sickle cell disease and cerebrovascular stroke: a preventable event.
Simões, Ana Sofia
title_short Sickle cell disease and cerebrovascular stroke: a preventable event.
title_full Sickle cell disease and cerebrovascular stroke: a preventable event.
title_fullStr Sickle cell disease and cerebrovascular stroke: a preventable event.
title_full_unstemmed Sickle cell disease and cerebrovascular stroke: a preventable event.
title_sort Sickle cell disease and cerebrovascular stroke: a preventable event.
author Simões, Ana Sofia
author_facet Simões, Ana Sofia
Garcia, Pedro
Fernandes, Isabel
Ventura, Lurdes
Silva, Rita
Barata, Deolinda
author_role author
author2 Garcia, Pedro
Fernandes, Isabel
Ventura, Lurdes
Silva, Rita
Barata, Deolinda
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Simões, Ana Sofia
Garcia, Pedro
Fernandes, Isabel
Ventura, Lurdes
Silva, Rita
Barata, Deolinda
description About 75% of the children presenting with cerebrovascular stroke have an identified cause. For black children, the most common underlying condition is sickle cell disease. This case report describes a preventable natural history, with an unusual presenting feature.27th month black infant without relevant background, presented with an acute focal neurological deficit. Brain computed tomography scan showed extensive acute infarction, and magnetic resonance also revealed previous silent cerebral infarct. Blood sample showed normocytic anemia and spontaneous sickling of the red blood cells, with 87% hemoglobin S. Exchange transfusion was made.Stroke, as a sickle cell disease complication, can occur at early ages and being the presenting sign. We consider that it would be worth spread the antenatal hemoglobinopathy screening programme, and evaluating the cost-effectiveness of a neonatal screening programme for sickle cell disease in Portugal.
publishDate 2011
dc.date.none.fl_str_mv 2011-12-12
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/475
oai:ojs.www.actamedicaportuguesa.com:article/475
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/475
identifier_str_mv oai:ojs.www.actamedicaportuguesa.com:article/475
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/475
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/475/183
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 24 No. 4 (2011): Julho-Agosto; 637-40
Acta Médica Portuguesa; Vol. 24 N.º 4 (2011): Julho-Agosto; 637-40
1646-0758
0870-399X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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